Ub-G76V-GFP Citations (34)
Originally described in: Short-lived green fluorescent proteins for quantifying ubiquitin/proteasome-dependent proteolysis in living cells.Dantuma NP, Lindsten K, Glas R, Jellne M, Masucci MG Nat Biotechnol. 2000 May . 18(5):538-43. PubMed Journal
Articles Citing Ub-G76V-GFP
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| Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolites. Serra-Perez A, Planas AM, Nunez-O'Mara A, Berra E, Garcia-Villoria J, Ribes A, Santalucia T. J Biol Chem. 2010 Jun 11;285(24):18217-24. doi: 10.1074/jbc.M110.101048. Epub 2010 Apr 5. PubMed |
| Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation. Halawani D, Tessier S, Anzellotti D, Bennett DA, Latterich M, LeBlanc AC. J Neurosci. 2010 Apr 28;30(17):6132-42. doi: 10.1523/JNEUROSCI.5874-09.2010. PubMed |
| A photoconvertible reporter of the ubiquitin-proteasome system in vivo. Hamer G, Matilainen O, Holmberg CI. Nat Methods. 2010 Jun;7(6):473-8. doi: 10.1038/nmeth.1460. Epub 2010 May 9. PubMed |
| The UBX protein SAKS1 negatively regulates endoplasmic reticulum-associated degradation and p97-dependent degradation. LaLonde DP, Bretscher A. J Biol Chem. 2011 Feb 11;286(6):4892-901. doi: 10.1074/jbc.M110.158030. Epub 2010 Dec 6. PubMed |
| Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia. Deng HX, Chen W, Hong ST, Boycott KM, Gorrie GH, Siddique N, Yang Y, Fecto F, Shi Y, Zhai H, Jiang H, Hirano M, Rampersaud E, Jansen GH, Donkervoort S, Bigio EH, Brooks BR, Ajroud K, Sufit RL, Haines JL, Mugnaini E, Pericak-Vance MA, Siddique T. Nature. 2011 Aug 21;477(7363):211-5. doi: 10.1038/nature10353. PubMed |
| The Ubiquitin ligase Ubr11 is essential for oligopeptide utilization in the fission yeast Schizosaccharomyces pombe. Kitamura K, Nakase M, Tohda H, Takegawa K. Eukaryot Cell. 2012 Mar;11(3):302-10. doi: 10.1128/EC.05253-11. Epub 2012 Jan 6. PubMed |
| Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS. Gonzalez-Perez P, Lu Y, Chian RJ, Sapp PC, Tanzi RE, Bertram L, McKenna-Yasek D, Gao FB, Brown RH Jr. Neurobiol Dis. 2012 Dec;48(3):391-8. doi: 10.1016/j.nbd.2012.06.018. Epub 2012 Jul 3. PubMed |
| Excitotoxic stimulation downregulates the ubiquitin-proteasome system through activation of NMDA receptors in cultured hippocampal neurons. Caldeira MV, Curcio M, Leal G, Salazar IL, Mele M, Santos AR, Melo CV, Pereira P, Canzoniero LM, Duarte CB. Biochim Biophys Acta. 2013 Jan;1832(1):263-74. doi: 10.1016/j.bbadis.2012.10.009. Epub 2012 Oct 13. PubMed |
| Synthesis and screening of 3-MA derivatives for autophagy inhibitors. Wu Y, Wang X, Guo H, Zhang B, Zhang XB, Shi ZJ, Yu L. Autophagy. 2013 Apr;9(4):595-603. doi: 10.4161/auto.23641. Epub 2013 Feb 14. PubMed |
| Insulin/IGF-1 signaling regulates proteasome activity through the deubiquitinating enzyme UBH-4. Matilainen O, Arpalahti L, Rantanen V, Hautaniemi S, Holmberg CI. Cell Rep. 2013 Jun 27;3(6):1980-95. doi: 10.1016/j.celrep.2013.05.012. Epub 2013 Jun 13. PubMed |
| Zinc ionophores pyrithione inhibits herpes simplex virus replication through interfering with proteasome function and NF-kappaB activation. Qiu M, Chen Y, Chu Y, Song S, Yang N, Gao J, Wu Z. Antiviral Res. 2013 Oct;100(1):44-53. doi: 10.1016/j.antiviral.2013.07.001. Epub 2013 Jul 15. PubMed |
| Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin-proteasome system. Yagi T, Ito D, Suzuki N. Neurobiol Dis. 2014 Jun;66:83-91. doi: 10.1016/j.nbd.2014.02.011. Epub 2014 Mar 5. PubMed |
| The selenium metabolite methylselenol regulates the expression of ligands that trigger immune activation through the lymphocyte receptor NKG2D. Hagemann-Jensen M, Uhlenbrock F, Kehlet S, Andresen L, Gabel-Jensen C, Ellgaard L, Gammelgaard B, Skov S. J Biol Chem. 2014 Nov 7;289(45):31576-90. doi: 10.1074/jbc.M114.591537. Epub 2014 Sep 25. PubMed |
| Docosahexaenoic acid induces the degradation of HPV E6/E7 oncoproteins by activating the ubiquitin-proteasome system. Jing K, Shin S, Jeong S, Kim S, Song KS, Park JH, Heo JY, Seo KS, Park SK, Kweon GR, Wu T, Park JI, Lim K. Cell Death Dis. 2014 Nov 13;5:e1524. doi: 10.1038/cddis.2014.477. PubMed |
| Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS. Yamakawa M, Ito D, Honda T, Kubo K, Noda M, Nakajima K, Suzuki N. Hum Mol Genet. 2015 Mar 15;24(6):1630-45. doi: 10.1093/hmg/ddu576. Epub 2014 Nov 14. PubMed |
| Actin Cytoskeletal Organization in Drosophila Germline Ring Canals Depends on Kelch Function in a Cullin-RING E3 Ligase. Hudson AM, Mannix KM, Cooley L. Genetics. 2015 Nov;201(3):1117-31. doi: 10.1534/genetics.115.181289. Epub 2015 Sep 16. PubMed |
| Naturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating Enzymes. Lawson AP, Long MJ, Coffey RT, Qian Y, Weerapana E, El Oualid F, Hedstrom L. Cancer Res. 2015 Dec 1;75(23):5130-42. doi: 10.1158/0008-5472.CAN-15-1544. Epub 2015 Nov 5. PubMed |
| VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Shih YT, Hsueh YP. Nat Commun. 2016 Mar 17;7:11020. doi: 10.1038/ncomms11020. PubMed |
| The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates. Pinto MJ, Alves PL, Martins L, Pedro JR, Ryu HR, Jeon NL, Taylor AM, Almeida RD. J Cell Biol. 2016 Mar 28;212(7):789-801. doi: 10.1083/jcb.201509039. PubMed |
| Structure-Based Design of beta5c Selective Inhibitors of Human Constitutive Proteasomes. Xin BT, de Bruin G, Huber EM, Besse A, Florea BI, Filippov DV, van der Marel GA, Kisselev AF, van der Stelt M, Driessen C, Groll M, Overkleeft HS. J Med Chem. 2016 Aug 11;59(15):7177-87. doi: 10.1021/acs.jmedchem.6b00705. Epub 2016 Aug 1. PubMed |
| Nitric Oxide Upregulates Proteasomal Protein Degradation in Neurons. Bal N, Roshchin M, Salozhin S, Balaban P. Cell Mol Neurobiol. 2016 Aug 5. PubMed |
| The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity. Huang ZN, Her LS. Mol Neurobiol. 2016 Nov 5. PubMed |
| Structural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging. Cornils A, Maurya AK, Tereshko L, Kennedy J, Brear AG, Prahlad V, Blacque OE, Sengupta P. PLoS Genet. 2016 Dec 1;12(12):e1006325. doi: 10.1371/journal.pgen.1006325. eCollection 2016 Dec. PubMed |
| PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins. Hall EA, Nahorski MS, Murray LM, Shaheen R, Perkins E, Dissanayake KN, Kristaryanto Y, Jones RA, Vogt J, Rivagorda M, Handley MT, Mali GR, Quidwai T, Soares DC, Keighren MA, McKie L, Mort RL, Gammoh N, Garcia-Munoz A, Davey T, Vermeren M, Walsh D, Budd P, Aligianis IA, Faqeih E, Quigley AJ, Jackson IJ, Kulathu Y, Jackson M, Ribchester RR, von Kriegsheim A, Alkuraya FS, Woods CG, Maher ER, Mill P. Am J Hum Genet. 2017 May 4;100(5):706-724. doi: 10.1016/j.ajhg.2017.03.008. Epub 2017 Apr 13. PubMed |
| A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis. Edens BM, Yan J, Miller N, Deng HX, Siddique T, Ma YC. Elife. 2017 May 2;6. pii: e25453. doi: 10.7554/eLife.25453. PubMed |
| Proteasome inhibition promotes autophagy and protects from endoplasmic reticulum stress in rat alveolar macrophages exposed to hypoxia-reoxygenation injury. Fan T, Huang Z, Wang W, Zhang B, Xu Y, Mao Z, Chen L, Hu H, Geng Q. J Cell Physiol. 2018 Oct;233(10):6748-6758. doi: 10.1002/jcp.26516. Epub 2018 May 9. PubMed |
| Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology. Lee YC, Huang WC, Lin JH, Kao TJ, Lin HC, Lee KH, Lin HC, Shen CJ, Chang WC, Huang CC. J Biomed Sci. 2018 Nov 8;25(1):76. doi: 10.1186/s12929-018-0479-4. PubMed |
| Proteasome Inhibition in Multiple Myeloma: Head-to-Head Comparison of Currently Available Proteasome Inhibitors. Besse A, Besse L, Kraus M, Mendez-Lopez M, Bader J, Xin BT, de Bruin G, Maurits E, Overkleeft HS, Driessen C. Cell Chem Biol. 2019 Mar 21;26(3):340-351.e3. doi: 10.1016/j.chembiol.2018.11.007. Epub 2019 Jan 3. PubMed |
| Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition. Towers CG, Fitzwalter BE, Regan D, Goodspeed A, Morgan MJ, Liu CW, Gustafson DL, Thorburn A. Dev Cell. 2019 Sep 23;50(6):690-703.e6. doi: 10.1016/j.devcel.2019.07.010. Epub 2019 Aug 1. PubMed |
| Ochratoxin A Sequentially Activates Autophagy and the Ubiquitin-Proteasome System. Akpinar HA, Kahraman H, Yaman I. Toxins (Basel). 2019 Oct 24;11(11). pii: toxins11110615. doi: 10.3390/toxins11110615. PubMed |
| Nelfinavir Inhibits the TCF11/Nrf1-Mediated Proteasome Recovery Pathway in Multiple Myeloma. Fassmannova D, Sedlak F, Sedlacek J, Spicka I, Grantz Saskova K. Cancers (Basel). 2020 Apr 25;12(5). pii: cancers12051065. doi: 10.3390/cancers12051065. PubMed |
| Increased AMP deaminase activity decreases ATP content and slows protein degradation in cultured skeletal muscle. Davis PR, Miller SG, Verhoeven NA, Morgan JS, Tulis DA, Witczak CA, Brault JJ. Metabolism. 2020 Jul;108:154257. doi: 10.1016/j.metabol.2020.154257. Epub 2020 May 1. PubMed |
| Proteasomal inhibition preferentially stimulates lysosome activity relative to autophagic flux in primary astrocytes. Yuan R, Hahn Y, Stempel MH, Sidibe DK, Laxton O, Chen J, Kulkarni A, Maday S. Autophagy. 2023 Feb;19(2):570-596. doi: 10.1080/15548627.2022.2084884. Epub 2022 Jun 19. PubMed |
VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates.
Mirsanaye AS, Hoffmann S, Weisser M, Mund A, Lopez Mendez B, Typas D, van den Boom J, Benedict B, Hendriks IA, Nielsen ML, Meyer H, Duxin JP, Montoya G, Mailand N.
Nat Commun. 2024 Mar 19;15(1):2459. doi: 10.1038/s41467-024-46760-4.
PubMed
Associated Plasmids |
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