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GFP-Ub Citations (40)

Originally described in: A dynamic ubiquitin equilibrium couples proteasomal activity to chromatin remodeling.
Dantuma NP, Groothuis TA, Salomons FA, Neefjes J J Cell Biol. 2006 Apr 10. 173(1):19-26.
PubMed Journal

Articles Citing GFP-Ub

Articles
The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. Carrettiero DC, Hernandez I, Neveu P, Papagiannakopoulos T, Kosik KS. J Neurosci. 2009 Feb 18;29(7):2151-61. doi: 10.1523/JNEUROSCI.4660-08.2009. PubMed
Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death. Grasso D, Ropolo A, Lo Re A, Boggio V, Molejon MI, Iovanna JL, Gonzalez CD, Urrutia R, Vaccaro MI. J Biol Chem. 2011 Mar 11;286(10):8308-24. doi: 10.1074/jbc.M110.197301. Epub 2010 Dec 20. PubMed
Temporal profiling of orexin receptor-arrestin-ubiquitin complexes reveals differences between receptor subtypes. Dalrymple MB, Jaeger WC, Eidne KA, Pfleger KD. J Biol Chem. 2011 May 13;286(19):16726-33. doi: 10.1074/jbc.M111.223537. Epub 2011 Mar 4. PubMed
Heterogeneity in the kinetics of nuclear proteins and trajectories of substructures associated with heterochromatin. Stixova L, Bartova E, Matula P, Danek O, Legartova S, Kozubek S. Epigenetics Chromatin. 2011 Mar 18;4:5. doi: 10.1186/1756-8935-4-5. PubMed
Supervillin-mediated suppression of p53 protein enhances cell survival. Fang Z, Luna EJ. J Biol Chem. 2013 Mar 15;288(11):7918-29. doi: 10.1074/jbc.M112.416842. Epub 2013 Feb 4. PubMed
Mesenchymal bone marrow stem cells within polyglycolic acid tube observed in vivo after six weeks enhance facial nerve regeneration. Costa HJ, Ferreira Bento R, Salomone R, Azzi-Nogueira D, Zanatta DB, Paulino Costa M, da Silva CF, Strauss BE, Haddad LA. Brain Res. 2013 May 13;1510:10-21. doi: 10.1016/j.brainres.2013.03.025. Epub 2013 Mar 28. PubMed
Spatiotemporally controlled induction of autophagy-mediated lysosome turnover. Hung YH, Chen LM, Yang JY, Yang WY. Nat Commun. 2013;4:2111. doi: 10.1038/ncomms3111. PubMed
Bit-by-bit autophagic removal of parkin-labelled mitochondria. Yang JY, Yang WY. Nat Commun. 2013;4:2428. doi: 10.1038/ncomms3428. PubMed
The ubiquitin-proteasome system regulates the stability and activity of the glucose sensor glucokinase in pancreatic beta-cells. Hofmeister-Brix A, Lenzen S, Baltrusch S. Biochem J. 2013 Dec 1;456(2):173-84. doi: 10.1042/BJ20130262. PubMed
The Polycomb group protein RING1B is overexpressed in ductal breast carcinoma and is required to sustain FAK steady state levels in breast cancer epithelial cells. Bosch A, Panoutsopoulou K, Corominas JM, Gimeno R, Moreno-Bueno G, Martin-Caballero J, Morales S, Lobato T, Martinez-Romero C, Farias EF, Mayol X, Cano A, Hernandez-Munoz I. Oncotarget. 2014 Apr 30;5(8):2065-76. PubMed
Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase. Hamacher-Brady A, Choe SC, Krijnse-Locker J, Brady NR. Cell Death Differ. 2014 Dec;21(12):1862-76. doi: 10.1038/cdd.2014.101. Epub 2014 Aug 1. PubMed
Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms. Prado M, Eickel N, De Niz M, Heitmann A, Agop-Nersesian C, Wacker R, Schmuckli-Maurer J, Caldelari R, Janse CJ, Khan SM, May J, Meyer CG, Heussler VT. Autophagy. 2015;11(9):1561-79. doi: 10.1080/15548627.2015.1067361. PubMed
Ibuprofen Induces Mitochondrial-Mediated Apoptosis Through Proteasomal Dysfunction. Upadhyay A, Amanullah A, Chhangani D, Joshi V, Mishra R, Mishra A. Mol Neurobiol. 2015 Dec 15. PubMed
Cisplatin enhances NK cell immunotherapy efficacy to suppress HCC progression via altering the androgen receptor (AR)-ULBP2 signals. Shi L, Lin H, Li G, Sun Y, Shen J, Xu J, Yeh S, Cai X, Chang C. Cancer Lett. 2016 Jan 19. pii: S0304-3835(16)00029-X. doi: 10.1016/j.canlet.2016.01.017. PubMed
The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates. Pinto MJ, Alves PL, Martins L, Pedro JR, Ryu HR, Jeon NL, Taylor AM, Almeida RD. J Cell Biol. 2016 Mar 28;212(7):789-801. doi: 10.1083/jcb.201509039. PubMed
Proteasomal Dysfunction Induced By Diclofenac Engenders Apoptosis Through Mitochondrial Pathway. Amanullah A, Upadhyay A, Chhangani D, Joshi V, Mishra R, Yamanaka K, Mishra A. J Cell Biochem. 2016 Aug 2. doi: 10.1002/jcb.25666. PubMed
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease. Zhou Q, Yu X, Demirkaya E, Deuitch N, Stone D, Tsai WL, Kuehn HS, Wang H, Yang D, Park YH, Ombrello AK, Blake M, Romeo T, Remmers EF, Chae JJ, Mullikin JC, Guzel F, Milner JD, Boehm M, Rosenzweig SD, Gadina M, Welch SB, Ozen S, Topaloglu R, Abinun M, Kastner DL, Aksentijevich I. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10127-32. doi: 10.1073/pnas.1612594113. Epub 2016 Aug 24. PubMed
ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins. Villarroya-Beltri C, Baixauli F, Mittelbrunn M, Fernandez-Delgado I, Torralba D, Moreno-Gonzalo O, Baldanta S, Enrich C, Guerra S, Sanchez-Madrid F. Nat Commun. 2016 Nov 24;7:13588. doi: 10.1038/ncomms13588. PubMed
Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Li GB, Fu RQ, Shen HM, Zhou J, Hu XY, Liu YX, Li YN, Zhang HW, Liu X, Zhang YH, Huang C, Zhang R, Gao N. Oncotarget. 2017 Feb 7;8(6):10359-10374. doi: 10.18632/oncotarget.14413. PubMed
The peroxisomal AAA ATPase complex prevents pexophagy and development of peroxisome biogenesis disorders. Law KB, Bronte-Tinkew D, Di Pietro E, Snowden A, Jones RO, Moser A, Brumell JH, Braverman N, Kim PK. Autophagy. 2017 May 4;13(5):868-884. doi: 10.1080/15548627.2017.1291470. PubMed
Inverted recruitment of autophagy proteins to the Plasmodium berghei parasitophorous vacuole membrane. Schmuckli-Maurer J, Reber V, Wacker R, Bindschedler A, Zakher A, Heussler VT. PLoS One. 2017 Aug 25;12(8):e0183797. doi: 10.1371/journal.pone.0183797. eCollection 2017. PubMed
HSPB8 and BAG3 cooperate to promote spatial sequestration of ubiquitinated proteins and coordinate the cellular adaptive response to proteasome insufficiency. Guilbert SM, Lambert H, Rodrigue MA, Fuchs M, Landry J, Lavoie JN. FASEB J. 2018 Jul;32(7):3518-3535. doi: 10.1096/fj.201700558RR. Epub 2018 Feb 5. PubMed
SOD1(A4V) aggregation alters ubiquitin homeostasis in a cell model of ALS. Farrawell NE, Lambert-Smith I, Mitchell K, McKenna J, McAlary L, Ciryam P, Vine KL, Saunders DN, Yerbury JJ. J Cell Sci. 2018 Jun 12;131(11). pii: jcs.209122. doi: 10.1242/jcs.209122. PubMed
UBL3 modification influences protein sorting to small extracellular vesicles. Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K. Nat Commun. 2018 Sep 26;9(1):3936. doi: 10.1038/s41467-018-06197-y. PubMed
Lamin B is a target for selective nuclear PQC by BAG3: implication for nuclear envelopathies. Gupta MK, Gordon J, Glauser GM, Myers VD, Feldman AM, Cheung JY, Khalili K. Cell Death Dis. 2019 Jan 10;10(1):23. doi: 10.1038/s41419-018-1255-9. PubMed
Omegasome-proximal PtdIns(4,5)P2 couples F-actin mediated mitoaggregate disassembly with autophagosome formation during mitophagy. Hsieh CW, Yang WY. Nat Commun. 2019 Feb 27;10(1):969. doi: 10.1038/s41467-019-08924-5. PubMed
Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR). Goodman DE, Pretto CD, Krepostman TA, Carnahan KE, Spindler KR. MBio. 2019 Apr 23;10(2). pii: mBio.00668-19. doi: 10.1128/mBio.00668-19. PubMed
Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking. Lorenz-Guertin JM, Bambino MJ, Das S, Weintraub ST, Jacob TC. Front Cell Neurosci. 2019 Apr 26;13:163. doi: 10.3389/fncel.2019.00163. eCollection 2019. PubMed
Activation of the macroautophagy pathway by Yersinia enterocolitica promotes intracellular multiplication and egress of yersiniae from epithelial cells. Valencia Lopez MJ, Schimmeck H, Gropengiesser J, Middendorf L, Quitmann M, Schneider C, Holstermann B, Wacker R, Heussler V, Reimer R, Aepfelbacher M, Ruckdeschel K. Cell Microbiol. 2019 May 17:e13046. doi: 10.1111/cmi.13046. PubMed
Mitochondrial Protein Poldip2 (Polymerase Delta Interacting Protein 2) Controls Vascular Smooth Muscle Differentiated Phenotype by O-Linked GlcNAc (N-Acetylglucosamine) Transferase-Dependent Inhibition of a Ubiquitin Proteasome System. Paredes F, Williams HC, Quintana RA, San Martin A. Circ Res. 2020 Jan 3;126(1):41-56. doi: 10.1161/CIRCRESAHA.119.315932. Epub 2019 Oct 28. PubMed
Functional Autophagic Flux Regulates AgNP Uptake And The Internalized Nanoparticles Determine Tumor Cell Fate By Temporally Regulating Flux. Fageria L, Bambroo V, Mathew A, Mukherjee S, Chowdhury R, Pande S. Int J Nanomedicine. 2019 Nov 20;14:9063-9076. doi: 10.2147/IJN.S222211. eCollection 2019. PubMed
Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons. Evans CS, Holzbaur EL. Elife. 2020 Jan 14;9. pii: 50260. doi: 10.7554/eLife.50260. PubMed
Hsc70/Stub1 promotes the removal of individual oxidatively stressed peroxisomes. Chen BH, Chang YJ, Lin S, Yang WY. Nat Commun. 2020 Oct 19;11(1):5267. doi: 10.1038/s41467-020-18942-3. PubMed
An activity-dependent local transport regulation via degradation and synthesis of KIF17 underlying cognitive flexibility. Iwata S, Morikawa M, Takei Y, Hirokawa N. Sci Adv. 2020 Dec 16;6(51). pii: 6/51/eabc8355. doi: 10.1126/sciadv.abc8355. Print 2020 Dec. PubMed
Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells. Saini H, Sharma H, Mukherjee S, Chowdhury S, Chowdhury R. Cancer Cell Int. 2021 Jan 14;21(1):52. doi: 10.1186/s12935-020-01720-y. PubMed
The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity. Frison M, Faccenda D, Abeti R, Rigon M, Strobbe D, England-Rendon BS, Cash D, Barnes K, Sadeghian M, Sajic M, Wells LA, Xia D, Giunti P, Smith K, Mortiboys H, Turkheimer FE, Campanella M. Mol Psychiatry. 2021 Mar 4. pii: 10.1038/s41380-021-01050-z. doi: 10.1038/s41380-021-01050-z. PubMed
VPS13D promotes peroxisome biogenesis. Baldwin HA, Wang C, Kanfer G, Shah HV, Velayos-Baeza A, Dulovic-Mahlow M, Bruggemann N, Anding A, Baehrecke EH, Maric D, Prinz WA, Youle RJ. J Cell Biol. 2021 May 3;220(5). pii: 212018. doi: 10.1083/jcb.202001188. PubMed

Associated Plasmids

Deubiquitination of proteasome subunits by OTULIN regulates type I IFN production. Tao P, Wang S, Ozen S, Lee PY, Zhang J, Wang J, Han H, Yang Z, Fang R, Tsai WL, Yang H, Sag E, Topaloglu R, Aksentijevich I, Yu X, Zhou Q. Sci Adv. 2021 Nov 19;7(47):eabi6794. doi: 10.1126/sciadv.abi6794. Epub 2021 Nov 19. PubMed
Proteasomal inhibition preferentially stimulates lysosome activity relative to autophagic flux in primary astrocytes. Yuan R, Hahn Y, Stempel MH, Sidibe DK, Laxton O, Chen J, Kulkarni A, Maday S. Autophagy. 2023 Feb;19(2):570-596. doi: 10.1080/15548627.2022.2084884. Epub 2022 Jun 19. PubMed
CHIP Haploinsufficiency Exacerbates Hepatic Steatosis via Enhanced TXNIP Expression and Endoplasmic Reticulum Stress Responses. Han JH, Nam DH, Kim SH, Hwang AR, Park SY, Lim JH, Woo CH. Antioxidants (Basel). 2023 Feb 11;12(2):458. doi: 10.3390/antiox12020458. PubMed

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