Lox-Stop-Lox TOPO Citations (12)

Originally described in: Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras.
Jackson EL, Willis N, Mercer K, Bronson RT, Crowley D, Montoya R, Jacks T, Tuveson DA Genes Dev. 2001 Dec 15. 15(24):3243-8. PubMed Journal

---

Articles Citing Lox-Stop-Lox TOPO

Articles
A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice. Frescas D, de Lange T. Genes Dev. 2014 Jan 15;28(2):153-66. doi: 10.1101/gad.233395.113. PubMed
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. Nat Commun. 2014 Sep 5;2:4802. doi: 10.1038/ncomms5802. PubMed
Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins. Lee S, Kopp F, Chang TC, Sataluri A, Chen B, Sivakumar S, Yu H, Xie Y, Mendell JT. Cell. 2016 Jan 14;164(1-2):69-80. doi: 10.1016/j.cell.2015.12.017. Epub 2015 Dec 24. PubMed
Identification of novel loci for the generation of reporter mice. Rizzi N, Rebecchi M, Levandis G, Ciana P, Maggi A. Nucleic Acids Res. 2016 Nov 29. pii: gkw1142. PubMed
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Yu VWC, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT. Cell. 2017 Feb 23;168(5):944-945. doi: 10.1016/j.cell.2017.02.010. PubMed
Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury. Lin S, Nascimento EM, Gajera CR, Chen L, Neuhofer P, Garbuzov A, Wang S, Artandi SE. Nature. 2018 Apr;556(7700):244-248. doi: 10.1038/s41586-018-0004-7. Epub 2018 Apr 4. PubMed
Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load. Li HD, Cuevas I, Zhang M, Lu C, Alam MM, Fu YX, You MJ, Akbay EA, Zhang H, Castrillon DH. J Clin Invest. 2018 Aug 31;128(9):4179-4191. doi: 10.1172/JCI122095. Epub 2018 Aug 20. PubMed
Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression. Larson JD, Kasper LH, Paugh BS, Jin H, Wu G, Kwon CH, Fan Y, Shaw TI, Silveira AB, Qu C, Xu R, Zhu X, Zhang J, Russell HR, Peters JL, Finkelstein D, Xu B, Lin T, Tinkle CL, Patay Z, Onar-Thomas A, Pounds SB, McKinnon PJ, Ellison DW, Zhang J, Baker SJ. Cancer Cell. 2019 Jan 14;35(1):140-155.e7. doi: 10.1016/j.ccell.2018.11.015. Epub 2018 Dec 27. PubMed
Transcriptional repressor REST drives lineage stage-specific chromatin compaction at Ptch1 and increases AKT activation in a mouse model of medulloblastoma. Dobson THW, Tao RH, Swaminathan J, Maegawa S, Shaik S, Bravo-Alegria J, Sharma A, Kennis B, Yang Y, Callegari K, Haltom AR, Taylor P, Kogiso M, Qi L, Khatua S, Goldman S, Lulla RR, Fangusaro J, MacDonald TJ, Li XN, Hawkins C, Rajaram V, Gopalakrishnan V. Sci Signal. 2019 Jan 22;12(565). pii: 12/565/eaan8680. doi: 10.1126/scisignal.aan8680. PubMed
Renal plasticity revealed through reversal of polycystic kidney disease in mice. Dong K, Zhang C, Tian X, Coman D, Hyder F, Ma M, Somlo S. Nat Genet. 2021 Dec;53(12):1649-1663. doi: 10.1038/s41588-021-00946-4. Epub 2021 Oct 11. PubMed
Cyclophilin A as a Pro-Inflammatory Factor Exhibits Embryotoxic and Teratogenic Effects during Fetal Organogenesis. Kalinina A, Semenova M, Bruter A, Varlamova E, Kubekina M, Pavlenko N, Silaeva Y, Deikin A, Antoshina E, Gorkova T, Trukhanova L, Salmina A, Novikova S, Voronkov D, Kazansky D, Khromykh L. Int J Mol Sci. 2023 Jul 10;24(14):11279. doi: 10.3390/ijms241411279. PubMed
Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models. Hendrickson PG, Oristian KM, Browne MR, Luo L, Ma Y, Cardona DM, Linardic CM, Kirsch DG. Res Sq [Preprint]. 2023 Oct 29:rs.3.rs-3487637. doi: 10.21203/rs.3.rs-3487637/v1. PubMed

If you have published an article using this material, please email us at to have your article added to this page.