pCINeo-myc-Itch (C822S)/2860 Citations (3)

Originally described in: WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation.
Magnifico A, Ettenberg S, Yang C, Mariano J, Tiwari S, Fang S, Lipkowitz S, Weissman AM J Biol Chem. 2003 Oct 31. 278(44):43169-77. PubMed Journal

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Articles Citing pCINeo-myc-Itch (C822S)/2860

Articles
MKK4/SEK1 is negatively regulated through a feedback loop involving the E3 ubiquitin ligase itch. Ahn YH, Kurie JM. J Biol Chem. 2009 Oct 23;284(43):29399-404. doi: 10.1074/jbc.M109.044958. Epub 2009 Sep 8. PubMed
Ubiquitin ligase ITCH recruitment suppresses the aggregation and cellular toxicity of cytoplasmic misfolded proteins. Chhangani D, Upadhyay A, Amanullah A, Joshi V, Mishra A. Sci Rep. 2014 May 28;4:5077. doi: 10.1038/srep05077. PubMed
Itch E3 ubiquitin ligase positively regulates TGF-beta signaling to EMT via Smad7 ubiquitination. Park SH, Jung EH, Kim GY, Kim BC, Lim JH, Woo CH. Mol Cells. 2015 Jan 31;38(1):20-5. doi: 10.14348/molcells.2015.2120. Epub 2014 Dec 16. PubMed

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