p3s-Sniper-Cas9 Citations (5)
Originally described in: Directed evolution of CRISPR-Cas9 to increase its specificity.Lee JK, Jeong E, Lee J, Jung M, Shin E, Kim YH, Lee K, Jung I, Kim D, Kim S, Kim JS Nat Commun. 2018 Aug 6;9(1):3048. doi: 10.1038/s41467-018-05477-x. PubMed Journal
Articles Citing p3s-Sniper-Cas9
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Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9.
Choi GCG, Zhou P, Yuen CTL, Chan BKC, Xu F, Bao S, Chu HY, Thean D, Tan K, Wong KH, Zheng Z, Wong ASL.
Nat Methods. 2019 Aug;16(8):722-730. doi: 10.1038/s41592-019-0473-0. Epub 2019 Jul 15.
PubMed
Associated Plasmids |
Blackjack mutations improve the on-target activities of increased fidelity variants of SpCas9 with 5'G-extended sgRNAs.
Kulcsar PI, Talas A, Toth E, Nyeste A, Ligeti Z, Welker Z, Welker E.
Nat Commun. 2020 Mar 6;11(1):1223. doi: 10.1038/s41467-020-15021-5.
PubMed
Associated Plasmids
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| dupe-Precise and broad scope genome editing based on high-specificity Cas9 nickases. Wang Q, Liu J, Janssen JM, Le Bouteiller M, Frock RL, Goncalves MAFV. Nucleic Acids Res. 2021 Jan 25;49(2):1173-1198. doi: 10.1093/nar/gkaa1236. PubMed |
| Quantitative assessment of engineered Cas9 variants for target specificity enhancement by single-molecule reaction pathway analysis. Bak SY, Jung Y, Park J, Sung K, Jang HK, Bae S, Kim SK. Nucleic Acids Res. 2021 Nov 8;49(19):11312-11322. doi: 10.1093/nar/gkab858. PubMed |
A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets.
Kulcsar PI, Talas A, Ligeti Z, Toth E, Rakvacs Z, Bartos Z, Krausz SL, Welker A, Vegi VL, Huszar K, Welker E.
Nat Commun. 2023 Sep 16;14(1):5746. doi: 10.1038/s41467-023-41393-5.
PubMed
Associated Plasmids |
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