pAdDeltaF6 Citations (109)
Originally described in: AAV packaging plasmidsUnpublished
Articles Citing pAdDeltaF6
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Programmable RNA-Guided RNA Effector Proteins Built from Human Parts.
Rauch S, He E, Srienc M, Zhou H, Zhang Z, Dickinson BC.
Cell. 2019 Jun 27;178(1):122-134.e12. doi: 10.1016/j.cell.2019.05.049. Epub 2019 Jun 20.
PubMed
Associated Plasmids |
| GPR108 Is a Highly Conserved AAV Entry Factor. Dudek AM, Zabaleta N, Zinn E, Pillay S, Zengel J, Porter C, Franceschini JS, Estelien R, Carette JE, Zhou GL, Vandenberghe LH. Mol Ther. 2020 Feb 5;28(2):367-381. doi: 10.1016/j.ymthe.2019.11.005. Epub 2019 Nov 13. PubMed |
| Molecular elevation of insulin receptor signaling improves memory recall in aged Fischer 344 rats. Frazier HN, Anderson KL, Ghoweri AO, Lin RL, Hawkinson TR, Popa GJ, Sompol P, Mendenhall MD, Norris CM, Thibault O. Aging Cell. 2020 Oct;19(10):e13220. doi: 10.1111/acel.13220. Epub 2020 Aug 27. PubMed |
| CNS Transduction Benefits of AAV-PHP.eB over AAV9 Are Dependent on Administration Route and Mouse Strain. Mathiesen SN, Lock JL, Schoderboeck L, Abraham WC, Hughes SM. Mol Ther Methods Clin Dev. 2020 Oct 20;19:447-458. doi: 10.1016/j.omtm.2020.10.011. eCollection 2020 Dec 11. PubMed |
| AAV-mediated in vivo genome editing in vascular endothelial cells. Wu W, Yang Y, Yao F, Dong L, Xia X, Zhang S, Lei H. Methods. 2020 Dec 9. pii: S1046-2023(20)30263-2. doi: 10.1016/j.ymeth.2020.12.001. PubMed |
| Adeno-Associated Virus-Mediated Gene Therapy in the Mashlool, Atp1a3(Mashl/+), Mouse Model of Alternating Hemiplegia of Childhood. Hunanyan AS, Kantor B, Puranam RS, Elliott C, McCall A, Dhindsa J, Pagadala P, Wallace K, Poe J, Gunduz T, Asokan A, Koeberl DD, ElMallah MK, Mikati MA. Hum Gene Ther. 2021 Apr;32(7-8):405-419. doi: 10.1089/hum.2020.191. Epub 2021 Feb 12. PubMed |
| Hunger enhances food-odour attraction through a neuropeptide Y spotlight. Horio N, Liberles SD. Nature. 2021 Apr;592(7853):262-266. doi: 10.1038/s41586-021-03299-4. Epub 2021 Mar 3. PubMed |
| Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue. Miller LVC, Mukadam AS, Durrant CS, Vaysburd MJ, Katsinelos T, Tuck BJ, Sanford S, Sheppard O, Knox C, Cheng S, James LC, Coleman MP, McEwan WA. Acta Neuropathol Commun. 2021 Mar 12;9(1):41. doi: 10.1186/s40478-021-01141-6. PubMed |
| CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology. Xiao D, Zhang W, Wang Q, Li X, Zhang Y, Rasouli J, Casella G, Ciric B, Curtis M, Rostami A, Zhang GX. Mol Ther Methods Clin Dev. 2021 Feb 18;20:755-764. doi: 10.1016/j.omtm.2021.02.012. eCollection 2021 Mar 12. PubMed |
| CRISPR/Cas9 Mediated Deletion of the Angiotensinogen Gene Reduces Hypertension: A Potential for Cure? Sun H, Hodgkinson CP, Pratt RE, Dzau VJ. Hypertension. 2021 Jun;77(6):1990-2000. doi: 10.1161/HYPERTENSIONAHA.120.16870. Epub 2021 Apr 5. PubMed |
| Anterior thalamic dysfunction underlies cognitive deficits in a subset of neuropsychiatric disease models. Roy DS, Zhang Y, Aida T, Choi S, Chen Q, Hou Y, Lea NE, Skaggs KM, Quay JC, Liew M, Maisano H, Le V, Jones C, Xu J, Kong D, Sullivan HA, Saunders A, McCarroll SA, Wickersham IR, Feng G. Neuron. 2021 Aug 18;109(16):2590-2603.e13. doi: 10.1016/j.neuron.2021.06.005. Epub 2021 Jun 30. PubMed |
Compact RNA editors with small Cas13 proteins.
Kannan S, Altae-Tran H, Jin X, Madigan VJ, Oshiro R, Makarova KS, Koonin EV, Zhang F.
Nat Biotechnol. 2021 Aug 30. pii: 10.1038/s41587-021-01030-2. doi: 10.1038/s41587-021-01030-2.
PubMed
Associated Plasmids |
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
Wang LL, Serrano C, Zhong X, Ma S, Zou Y, Zhang CL.
Cell. 2021 Oct 14;184(21):5465-5481.e16. doi: 10.1016/j.cell.2021.09.005. Epub 2021 Sep 27.
PubMed
Associated Plasmids |
| NEK6 is an injury-responsive kinase cooperating with STAT3 in regulation of reactive astrogliosis. Yu Y, Shen T, Zhong X, Wang LL, Tai W, Zou Y, Qin J, Zhang Z, Zhang CL. Glia. 2022 Feb;70(2):273-286. doi: 10.1002/glia.24104. Epub 2021 Oct 13. PubMed |
| Proteomic Landscape of Adeno-Associated Virus (AAV)-Producing HEK293 Cells. Strasser L, Boi S, Guapo F, Donohue N, Barron N, Rainbow-Fletcher A, Bones J. Int J Mol Sci. 2021 Oct 25;22(21). pii: ijms222111499. doi: 10.3390/ijms222111499. PubMed |
| OGDHL ameliorates cognitive impairment and Alzheimer's disease-like pathology via activating Wnt/beta-catenin signaling in Alzheimer's disease mice. Yao L, Xu X, Xu Y, Li C, Xie F, Guo M, Liu Z, Liu X. Behav Brain Res. 2022 Feb 10;418:113673. doi: 10.1016/j.bbr.2021.113673. Epub 2021 Nov 16. PubMed |
| Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques. Arotcarena ML, Dovero S, Biendon N, Dutheil N, Planche V, Bezard E, Dehay B. Front Bioeng Biotechnol. 2021 Nov 15;9:762209. doi: 10.3389/fbioe.2021.762209. eCollection 2021. PubMed |
| Improved targeting of human CD4+ T cells by nanobody-modified AAV2 gene therapy vectors. Hamann MV, Beschorner N, Vu XK, Hauber I, Lange UC, Traenkle B, Kaiser PD, Foth D, Schneider C, Buning H, Rothbauer U, Hauber J. PLoS One. 2021 Dec 20;16(12):e0261269. doi: 10.1371/journal.pone.0261269. eCollection 2021. PubMed |
| A fast, aqueous, reversible three-day tissue clearing method for adult and embryonic mouse brain and whole body. Kosmidis S, Negrean A, Dranovsky A, Losonczy A, Kandel ER. Cell Rep Methods. 2021 Nov 22;1(7):100090. doi: 10.1016/j.crmeth.2021.100090. Epub 2021 Oct 11. PubMed |
| Optimized protocols for efficient gene editing in mouse hepatocytes in vivo using CRISPR-Cas9 technology. Chen Y, Ding Q. STAR Protoc. 2021 Dec 23;3(1):101062. doi: 10.1016/j.xpro.2021.101062. eCollection 2022 Mar 18. PubMed |
| Non-invasive administration of AAV to target lung parenchymal cells and develop SARS-CoV-2-susceptible mice. Yang MS, Park MJ, Lee J, Oh B, Kang KW, Kim Y, Lee SM, Lim JO, Jung TY, Park JH, Park SC, Lim YS, Hwang SB, Lyoo KS, Kim DI, Kim B. Mol Ther. 2022 May 4;30(5):1994-2004. doi: 10.1016/j.ymthe.2022.01.010. Epub 2022 Jan 7. PubMed |
| Brain-wide TVA compensation allows rabies virus to retrograde target cell-type-specific projection neurons. Han Z, Luo N, Kou J, Li L, Xu Z, Wei S, Wu Y, Wang J, Ye C, Lin K, Xu F. Mol Brain. 2022 Jan 29;15(1):13. doi: 10.1186/s13041-022-00898-8. PubMed |
| Only a small fraction of cells produce assembled capsids during transfection-based manufacturing of adeno-associated virus vectors. Dash S, Sharon DM, Mullick A, Kamen AA. Biotechnol Bioeng. 2022 Jun;119(6):1685-1690. doi: 10.1002/bit.28068. Epub 2022 Feb 28. PubMed |
Ratiometric Imaging of Mitochondrial Hydrogen Peroxide in Abeta42-Mediated Neurotoxicity.
Li X, Zhang Y, Ai HW.
ACS Sens. 2022 Feb 28. doi: 10.1021/acssensors.1c01381.
PubMed
Associated Plasmids |
| Traumatic-noise-induced hair cell death and hearing loss is mediated by activation of CaMKKbeta. Wu F, Hill K, Fang Q, He Z, Zheng H, Wang X, Xiong H, Sha SH. Cell Mol Life Sci. 2022 Apr 19;79(5):249. doi: 10.1007/s00018-022-04268-4. PubMed |
| m6A and YTHDF proteins contribute to the localization of select neuronal mRNAs. Flamand MN, Meyer KD. Nucleic Acids Res. 2022 May 6;50(8):4464-4483. doi: 10.1093/nar/gkac251. PubMed |
| CMYA5 establishes cardiac dyad architecture and positioning. Lu F, Ma Q, Xie W, Liou CL, Zhang D, Sweat ME, Jardin BD, Naya FJ, Guo Y, Cheng H, Pu WT. Nat Commun. 2022 Apr 21;13(1):2185. doi: 10.1038/s41467-022-29902-4. PubMed |
| FGF9 Alleviates the Fatty Liver Phenotype by Regulating Hepatic Lipid Metabolism. Zhao F, Zhang L, Zhang M, Huang J, Zhang J, Chang Y. Front Pharmacol. 2022 Apr 20;13:850128. doi: 10.3389/fphar.2022.850128. eCollection 2022. PubMed |
| Liver vitronectin release into the bloodstream increases due to reduced vagal muscarinic signaling after cerebral stroke in female mice. Keasey MP, Lovins C, Jia C, Hagg T. Physiol Rep. 2022 May;10(9):e15301. doi: 10.14814/phy2.15301. PubMed |
Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex.
Kato K, Zhou W, Okazaki S, Isayama Y, Nishizawa T, Gootenberg JS, Abudayyeh OO, Nishimasu H.
Cell. 2022 May 25. pii: S0092-8674(22)00581-5. doi: 10.1016/j.cell.2022.05.003.
PubMed
Associated Plasmids |
| Dietary intervention preserves beta cell function in mice through CTCF-mediated transcriptional reprogramming. Wang RR, Qiu X, Pan R, Fu H, Zhang Z, Wang Q, Chen H, Wu QQ, Pan X, Zhou Y, Shan P, Wang S, Guo G, Zheng M, Zhu L, Meng ZX. J Exp Med. 2022 Jul 4;219(7). pii: 213256. doi: 10.1084/jem.20211779. Epub 2022 Jun 2. PubMed |
| Somatic genetics analysis of sleep in adult mice. Wang G, Li Q, Xu J, Zhao S, Zhou R, Chen Z, Jiang W, Gao X, Zhou S, Chen Z, Sun Q, Ma C, Chen L, Shi B, Guo Y, Wang H, Wang X, Li H, Cai T, Wang Y, Chen Z, Wang F, Liu Q. J Neurosci. 2022 Jun 3. pii: JNEUROSCI.0089-22.2022. doi: 10.1523/JNEUROSCI.0089-22.2022. PubMed |
Neural circuit pathology driven by Shank3 mutation disrupts social behaviors.
Kim S, Kim YE, Song I, Ujihara Y, Kim N, Jiang YH, Yin HH, Lee TH, Kim IH.
Cell Rep. 2022 Jun 7;39(10):110906. doi: 10.1016/j.celrep.2022.110906.
PubMed
Associated Plasmids |
| Formation of False Context Fear Memory Is Regulated by Hypothalamic Corticotropin-Releasing Factor in Mice. Kasama E, Moriya M, Kamimura R, Matsuki T, Seki K. Int J Mol Sci. 2022 Jun 3;23(11). pii: ijms23116286. doi: 10.3390/ijms23116286. PubMed |
| Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue. Ojima K, Kakegawa W, Yamasaki T, Miura Y, Itoh M, Michibata Y, Kubota R, Doura T, Miura E, Nonaka H, Mizuno S, Takahashi S, Yuzaki M, Hamachi I, Kiyonaka S. Nat Commun. 2022 Jun 16;13(1):3167. doi: 10.1038/s41467-022-30828-0. PubMed |
| Targeting miR-30d reverses pathological cardiac hypertrophy. Li J, Sha Z, Zhu X, Xu W, Yuan W, Yang T, Jin B, Yan Y, Chen R, Wang S, Yao J, Xu J, Wang Z, Li G, Das S, Yang L, Xiao J. EBioMedicine. 2022 Jul;81:104108. doi: 10.1016/j.ebiom.2022.104108. Epub 2022 Jun 22. PubMed |
| PGE(2) -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase. Tao X, Du R, Guo S, Feng X, Yu T, OuYang Q, Chen Q, Fan X, Wang X, Guo C, Li X, Xue F, Chen S, Tong M, Lazarus M, Zuo S, Yu Y, Shen Y. EMBO J. 2022 Aug 16;41(16):e110439. doi: 10.15252/embj.2021110439. Epub 2022 Jul 4. PubMed |
A luciferase prosubstrate and a red bioluminescent calcium indicator for imaging neuronal activity in mice.
Tian X, Zhang Y, Li X, Xiong Y, Wu T, Ai HW.
Nat Commun. 2022 Jul 8;13(1):3967. doi: 10.1038/s41467-022-31673-x.
PubMed
Associated Plasmids |
A truncated reverse transcriptase enhances prime editing by split AAV vectors.
Gao Z, Ravendran S, Mikkelsen NS, Haldrup J, Cai H, Ding X, Paludan SR, Thomsen MK, Mikkelsen JG, Bak RO.
Mol Ther. 2022 Jul 8. pii: S1525-0016(22)00422-1. doi: 10.1016/j.ymthe.2022.07.001.
PubMed
Associated Plasmids |
| Single-shot AAV-vectored vaccine against SARS-CoV-2 with fast and long-lasting immunity. Wu F, Luo S, Zhang Y, Hairui Wang Zhaofei Guo Chunting He Shuting Bai Penghui He Min Jiang Xiaoyan Chen, Guangsheng Du Xun Sun YO. Acta Pharm Sin B. 2022 Jul 12. doi: 10.1016/j.apsb.2022.07.004. PubMed |
| TOB is an effector of the hippocampus-mediated acute stress response. Youssef MMM, Hamada HT, Lai ESK, Kiyama Y, El-Tabbal M, Kiyonari H, Nakano K, Kuhn B, Yamamoto T. Transl Psychiatry. 2022 Jul 29;12(1):302. doi: 10.1038/s41398-022-02078-7. PubMed |
| The intrinsic and extrinsic effects of TET proteins during gastrulation. Cheng S, Mittnenzweig M, Mayshar Y, Lifshitz A, Dunjic M, Rais Y, Ben-Yair R, Gehrs S, Chomsky E, Mukamel Z, Rubinstein H, Schlereth K, Reines N, Orenbuch AH, Tanay A, Stelzer Y. Cell. 2022 Aug 18;185(17):3169-3185.e20. doi: 10.1016/j.cell.2022.06.049. Epub 2022 Jul 30. PubMed |
| Downregulating PTBP1 fails to convert astrocytes into hippocampal neurons and to alleviate symptoms in Alzheimer's mouse models. Guo T, Pan X, Jiang G, Zhang D, Qi J, Shao L, Wang Z, Xu H, Zhao Y. J Neurosci. 2022 Aug 9;42(38):7309-17. doi: 10.1523/JNEUROSCI.1060-22.2022. PubMed |
| LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway. Chen T, Shi Z, Zhao Y, Meng X, Zhao S, Zheng L, Han X, Hu Z, Yao Q, Lin H, Du X, Zhang K, Han T, Hong W. BMC Med. 2022 Sep 29;20(1):335. doi: 10.1186/s12916-022-02523-w. PubMed |
| Gene therapy using human FMRP isoforms driven by the human FMR1 promoter rescues fragile X syndrome mouse deficits. Jiang Y, Han L, Meng J, Wang Z, Zhou Y, Yuan H, Xu H, Zhang X, Zhao Y, Lu J, Xu H, Zhang C, Zhang YW. Mol Ther Methods Clin Dev. 2022 Oct 7;27:246-258. doi: 10.1016/j.omtm.2022.10.002. eCollection 2022 Dec 8. PubMed |
| Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin. Kim H, Leng K, Park J, Sorets AG, Kim S, Shostak A, Embalabala RJ, Mlouk K, Katdare KA, Rose IVL, Sturgeon SM, Neal EH, Ao Y, Wang S, Sofroniew MV, Brunger JM, McMahon DG, Schrag MS, Kampmann M, Lippmann ES. Nat Commun. 2022 Nov 2;13(1):6581. doi: 10.1038/s41467-022-34412-4. PubMed |
| Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4. D'Amato G, Phansalkar R, Naftaly JA, Fan X, Amir ZA, Rios Coronado PE, Cowley DO, Quinn KE, Sharma B, Caron KM, Vigilante A, Red-Horse K. Dev Cell. 2022 Nov 21;57(22):2517-2532.e6. doi: 10.1016/j.devcel.2022.10.007. Epub 2022 Nov 7. PubMed |
| Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins. Vos DY, Wijers M, Smit M, Huijkman N, Kloosterhuis NJ, Wolters JC, Tissink JJ, Pronk ACM, Kooijman S, Rensen PCN, Kuivenhoven JA, van de Sluis B. Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):e29-e45. doi: 10.1161/ATVBAHA.122.318169. Epub 2022 Nov 10. PubMed |
| Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons. Liu PP, Dai SK, Mi TW, Tang GB, Wang Z, Wang H, Du HZ, Tang Y, Teng ZQ, Liu CM. EMBO Mol Med. 2022 Dec 7;14(12):e15795. doi: 10.15252/emmm.202215795. Epub 2022 Nov 17. PubMed |
| Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury. Frohlich A, Olde Heuvel F, Rehman R, Krishnamurthy SS, Li S, Li Z, Bayer D, Conquest A, Hagenston AM, Ludolph A, Huber-Lang M, Boeckers T, Knoll B, Morganti-Kossmann MC, Bading H, Roselli F. J Neuroinflammation. 2022 Nov 19;19(1):279. doi: 10.1186/s12974-022-02634-4. PubMed |
| DOK7 Promotes NMJ Regeneration After Nerve Injury. Kosco ED, Jing H, Chen P, Xiong WC, Samuels IS, Mei L. Mol Neurobiol. 2023 Mar;60(3):1453-1464. doi: 10.1007/s12035-022-03143-4. Epub 2022 Dec 5. PubMed |
Automated Image Analysis Reveals Different Localization of Synaptic Gephyrin C4 Splice Variants.
Liebsch F, Eggersmann FR, Merkler Y, Kloppenburg P, Schwarz G.
eNeuro. 2023 Jan 4;10(1):ENEURO.0102-22.2022. doi: 10.1523/ENEURO.0102-22.2022. Print 2023 Jan.
PubMed
Associated Plasmids |
| Delivering Base Editors In Vivo by Adeno-Associated Virus Vectors. Lim CKW, Miskalis AJ, Perez-Pinera P, Gaj T. Methods Mol Biol. 2023;2606:135-158. doi: 10.1007/978-1-0716-2879-9_11. PubMed |
| Protocol to map multi-transmitter neurons in the mouse brain using intersectional strategy. Xu J, Contractor A, Zhu Y. STAR Protoc. 2022 Dec 16;3(4):101907. doi: 10.1016/j.xpro.2022.101907. Epub 2022 Dec 6. PubMed |
| Lactate metabolism is essential in early-onset mitochondrial myopathy. Chen Z, Bordieanu B, Kesavan R, Lesner NP, Venigalla SSK, Shelton SD, DeBerardinis RJ, Mishra P. Sci Adv. 2023 Jan 4;9(1):eadd3216. doi: 10.1126/sciadv.add3216. Epub 2023 Jan 4. PubMed |
Optimization of base editors for the functional correction of SMN2 as a treatment for spinal muscular atrophy.
Alves CRR, Ha LL, Yaworski R, Sutton ER, Lazzarotto CR, Christie KA, Reilly A, Beauvais A, Doll RM, de la Cruz D, Maguire CA, Swoboda KJ, Tsai SQ, Kothary R, Kleinstiver BP.
Nat Biomed Eng. 2023 Dec 6. doi: 10.1038/s41551-023-01132-z.
PubMed
Associated Plasmids |
An updated suite of viral vectors for in vivo calcium imaging using intracerebral and retro-orbital injections in male mice.
Grodem S, Nymoen I, Vatne GH, Rogge FS, Bjornsdottir V, Lensjo KK, Fyhn M.
Nat Commun. 2023 Feb 4;14(1):608. doi: 10.1038/s41467-023-36324-3.
PubMed
Associated Plasmids |
| A rabies virus-based toolkit for efficient retrograde labeling and monosynaptic tracing. Lin KZ, Li L, Ma WY, Yang X, Han ZP, Luo NS, Wang J, Xu FQ. Neural Regen Res. 2023 Aug;18(8):1827-1833. doi: 10.4103/1673-5374.358618. PubMed |
| Intra-pituitary follicle-stimulating hormone signaling regulates hepatic lipid metabolism in mice. Qiao S, Alasmi S, Wyatt A, Wartenberg P, Wang H, Candlish M, Das D, Aoki M, Grunewald R, Zhou Z, Tian Q, Yu Q, Gotz V, Belkacemi A, Raza A, Ectors F, Kattler K, Gasparoni G, Walter J, Lipp P, Mollard P, Bernard DJ, Karatayli E, Karatayli SC, Lammert F, Boehm U. Nat Commun. 2023 Feb 25;14(1):1098. doi: 10.1038/s41467-023-36681-z. PubMed |
| Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis. Yu Q, Gamayun I, Wartenberg P, Zhang Q, Qiao S, Kusumakshi S, Candlish S, Gotz V, Wen S, Das D, Wyatt A, Wahl V, Ectors F, Kattler K, Yildiz D, Prevot V, Schwaninger M, Ternier G, Giacobini P, Ciofi P, Muller TD, Boehm U. Nat Commun. 2023 Mar 22;14(1):1588. doi: 10.1038/s41467-023-37099-3. PubMed |
| A custom-made AAV1 variant (AAV1-T593K) enables efficient transduction of Japanese quail neurons in vitro and in vivo. Zoabi S, Andreyanov M, Heinrich R, Ron S, Carmi I, Gutfreund Y, Berlin S. Commun Biol. 2023 Mar 28;6(1):337. doi: 10.1038/s42003-023-04712-6. PubMed |
| Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease. Wang Z, Zhu S, Jia Y, Wang Y, Kubota N, Fujiwara N, Gordillo R, Lewis C, Zhu M, Sharma T, Li L, Zeng Q, Lin YH, Hsieh MH, Gopal P, Wang T, Hoare M, Campbell P, Hoshida Y, Zhu H. bioRxiv. 2023 Mar 21:2023.03.20.533505. doi: 10.1101/2023.03.20.533505. Preprint. PubMed |
| Genomic investigations of unexplained acute hepatitis in children. Morfopoulou S, Buddle S, Torres Montaguth OE, Atkinson L, Guerra-Assuncao JA, Moradi Marjaneh M, Zennezini Chiozzi R, Storey N, Campos L, Hutchinson JC, Counsell JR, Pollara G, Roy S, Venturini C, Antinao Diaz JF, Siam A, Tappouni LJ, Asgarian Z, Ng J, Hanlon KS, Lennon A, McArdle A, Czap A, Rosenheim J, Andrade C, Anderson G, Lee JCD, Williams R, Williams CA, Tutill H, Bayzid N, Martin Bernal LM, Macpherson H, Montgomery KA, Moore C, Templeton K, Neill C, Holden M, Gunson R, Shepherd SJ, Shah P, Cooray S, Voice M, Steele M, Fink C, Whittaker TE, Santilli G, Gissen P, Kaufer BB, Reich J, Andreani J, Simmonds P, Alrabiah DK, Castellano S, Chikowore P, Odam M, Rampling T, Houlihan C, Hoschler K, Talts T, Celma C, Gonzalez S, Gallagher E, Simmons R, Watson C, Mandal S, Zambon M, Chand M, Hatcher J, De S, Baillie K, Semple MG, Martin J, Ushiro-Lumb I, Noursadeghi M, Deheragoda M, Hadzic N, Grammatikopoulos T, Brown R, Kelgeri C, Thalassinos K, Waddington SN, Jacques TS, Thomson E, Levin M, Brown JR, Breuer J. Nature. 2023 May;617(7961):564-573. doi: 10.1038/s41586-023-06003-w. Epub 2023 Mar 30. PubMed |
| Role of TMEM100 in mechanically insensitive nociceptor un-silencing. Nees TA, Wang N, Adamek P, Zeitzschel N, Verkest C, La Porta C, Schaefer I, Virnich J, Balkaya S, Prato V, Morelli C, Begay V, Lee YJ, Tappe-Theodor A, Lewin GR, Heppenstall PA, Taberner FJ, Lechner SG. Nat Commun. 2023 Apr 5;14(1):1899. doi: 10.1038/s41467-023-37602-w. PubMed |
| In vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration. Lin YH, Zeng Q, Jia Y, Wang Z, Li L, Hsieh MH, Cheng Q, Pagani CA, Livingston N, Lee J, Zhang Y, Sharma T, Siegwart DJ, Yimlamai D, Levi B, Zhu H. Hepatology. 2023 Oct 1;78(4):1133-1148. doi: 10.1097/HEP.0000000000000402. Epub 2023 Apr 12. PubMed |
| Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. Wang Y, Hurley A, De Giorgi M, Tanner MR, Hu RC, Pennington MW, Lagor WR, Beeton C. PLoS One. 2023 Apr 11;18(4):e0283996. doi: 10.1371/journal.pone.0283996. eCollection 2023. PubMed |
| Computer-Aided Directed Evolution Generates Novel AAV Variants with High Transduction Efficiency. Han Z, Luo N, Wang F, Cai Y, Yang X, Feng W, Zhu Z, Wang J, Wu Y, Ye C, Lin K, Xu F. Viruses. 2023 Mar 26;15(4):848. doi: 10.3390/v15040848. PubMed |
| Efficient cancer modeling through CRISPR-Cas9/HDR-based somatic precision gene editing in mice. Bu W, Creighton CJ, Heavener KS, Gutierrez C, Dou Y, Ku AT, Zhang Y, Jiang W, Urrutia J, Jiang W, Yue F, Jia L, Ibrahim AA, Zhang B, Huang S, Li Y. Sci Adv. 2023 May 12;9(19):eade0059. doi: 10.1126/sciadv.ade0059. Epub 2023 May 12. PubMed |
| Acute Downregulation but Not Genetic Ablation of Murine MCU Impairs Suppressive Capacity of Regulatory CD4 T Cells. Jost P, Klein F, Brand B, Wahl V, Wyatt A, Yildiz D, Boehm U, Niemeyer BA, Vaeth M, Alansary D. Int J Mol Sci. 2023 Apr 24;24(9):7772. doi: 10.3390/ijms24097772. PubMed |
| USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer. Maier CR, Hartmann O, Prieto-Garcia C, Al-Shami KM, Schlicker L, Vogel FCE, Haid S, Klann K, Buck V, Munch C, Schmitz W, Einig E, Krenz B, Calzado MA, Eilers M, Popov N, Rosenfeldt MT, Diefenbacher ME, Schulze A. Cell Death Differ. 2023 Jul;30(7):1710-1725. doi: 10.1038/s41418-023-01173-6. Epub 2023 May 18. PubMed |
| Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior. Al-Kachak A, Fulton SL, Di Salvo G, Chan JC, Farrelly LA, Lepack AE, Bastle RM, Kong L, Cathomas F, Newman EL, Menard C, Ramakrishnan A, Safovich P, Lyu Y, Covington HE 3rd, Shen L, Gleason K, Tamminga CA, Russo SJ, Maze I. bioRxiv [Preprint]. 2023 Sep 16:2023.05.04.539464. doi: 10.1101/2023.05.04.539464. PubMed |
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