pAAV2/8 Citations (33)
Originally described in: AAV packaging plasmidsUnpublished
Articles Citing pAAV2/8
Articles |
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AAV vectors engineered to target insulin receptor greatly enhance intramuscular gene delivery. Jackson CB, Richard AS, Ojha A, Conkright KA, Trimarchi JM, Bailey CC, Alpert MD, Kay MA, Farzan M, Choe H. Mol Ther Methods Clin Dev. 2020 Nov 17;19:496-506. doi: 10.1016/j.omtm.2020.11.004. eCollection 2020 Dec 11. PubMed |
Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness. Rankovic V, Vogl C, Dorje NM, Bahader I, Duque-Afonso CJ, Thirumalai A, Weber T, Kusch K, Strenzke N, Moser T. Front Mol Neurosci. 2021 Jan 7;13:600051. doi: 10.3389/fnmol.2020.600051. eCollection 2020. PubMed |
A Crucial Role of ACBD3 Required for Coxsackievirus Infection in Animal Model Developed by AAV-Mediated CRISPR Genome Editing Technique. Shin HJ, Ku KB, Kim S, Kim HS, Kim YS, Kim BT, Kim SJ, Kim C. Viruses. 2021 Feb 3;13(2). pii: v13020237. doi: 10.3390/v13020237. PubMed |
CRISPR/Cas9 Mediated Deletion of the Angiotensinogen Gene Reduces Hypertension: A Potential for Cure? Sun H, Hodgkinson CP, Pratt RE, Dzau VJ. Hypertension. 2021 Jun;77(6):1990-2000. doi: 10.1161/HYPERTENSIONAHA.120.16870. Epub 2021 Apr 5. PubMed |
Revisiting astrocyte to neuron conversion with lineage tracing in vivo.
Wang LL, Serrano C, Zhong X, Ma S, Zou Y, Zhang CL.
Cell. 2021 Oct 14;184(21):5465-5481.e16. doi: 10.1016/j.cell.2021.09.005. Epub 2021 Sep 27.
PubMed
Associated Plasmids |
Impaired glucocorticoid receptor expression in liver disrupts feeding-induced gene expression, glucose uptake, and glycogen storage. Praestholm SM, Correia CM, Goitea VE, Siersbaek MS, Jorgensen M, Havelund JF, Pedersen TA, Faergeman NJ, Grontved L. Cell Rep. 2021 Nov 2;37(5):109938. doi: 10.1016/j.celrep.2021.109938. PubMed |
Optimized protocols for efficient gene editing in mouse hepatocytes in vivo using CRISPR-Cas9 technology. Chen Y, Ding Q. STAR Protoc. 2021 Dec 23;3(1):101062. doi: 10.1016/j.xpro.2021.101062. eCollection 2022 Mar 18. PubMed |
Non-invasive administration of AAV to target lung parenchymal cells and develop SARS-CoV-2-susceptible mice. Yang MS, Park MJ, Lee J, Oh B, Kang KW, Kim Y, Lee SM, Lim JO, Jung TY, Park JH, Park SC, Lim YS, Hwang SB, Lyoo KS, Kim DI, Kim B. Mol Ther. 2022 May 4;30(5):1994-2004. doi: 10.1016/j.ymthe.2022.01.010. Epub 2022 Jan 7. PubMed |
Constitutively active STAT5b feminizes mouse liver gene expression.
Lau-Corona D, Ma H, Vergato C, Sarmento-Cabral A, Del Rio-Moreno M, Kineman RD, Waxman DJ.
Endocrinology. 2022 Apr 9. pii: 6565757. doi: 10.1210/endocr/bqac046.
PubMed
Associated Plasmids |
AAV-PHP.eB transduces both the inner and outer retina with high efficacy in mice. Palfi A, Chadderton N, Millington-Ward S, Post I, Humphries P, Kenna PF, Farrar GJ. Mol Ther Methods Clin Dev. 2022 Mar 28;25:236-249. doi: 10.1016/j.omtm.2022.03.016. eCollection 2022 Jun 9. PubMed |
FGF9 Alleviates the Fatty Liver Phenotype by Regulating Hepatic Lipid Metabolism. Zhao F, Zhang L, Zhang M, Huang J, Zhang J, Chang Y. Front Pharmacol. 2022 Apr 20;13:850128. doi: 10.3389/fphar.2022.850128. eCollection 2022. PubMed |
Liver vitronectin release into the bloodstream increases due to reduced vagal muscarinic signaling after cerebral stroke in female mice. Keasey MP, Lovins C, Jia C, Hagg T. Physiol Rep. 2022 May;10(9):e15301. doi: 10.14814/phy2.15301. PubMed |
Neural circuit pathology driven by Shank3 mutation disrupts social behaviors.
Kim S, Kim YE, Song I, Ujihara Y, Kim N, Jiang YH, Yin HH, Lee TH, Kim IH.
Cell Rep. 2022 Jun 7;39(10):110906. doi: 10.1016/j.celrep.2022.110906.
PubMed
Associated Plasmids |
A truncated reverse transcriptase enhances prime editing by split AAV vectors.
Gao Z, Ravendran S, Mikkelsen NS, Haldrup J, Cai H, Ding X, Paludan SR, Thomsen MK, Mikkelsen JG, Bak RO.
Mol Ther. 2022 Jul 8. pii: S1525-0016(22)00422-1. doi: 10.1016/j.ymthe.2022.07.001.
PubMed
Associated Plasmids |
The role of somatosensory innervation of adipose tissues.
Wang Y, Leung VH, Zhang Y, Nudell VS, Loud M, Servin-Vences MR, Yang D, Wang K, Moya-Garzon MD, Li VL, Long JZ, Patapoutian A, Ye L.
Nature. 2022 Sep;609(7927):569-574. doi: 10.1038/s41586-022-05137-7. Epub 2022 Aug 31.
PubMed
Associated Plasmids |
LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway. Chen T, Shi Z, Zhao Y, Meng X, Zhao S, Zheng L, Han X, Hu Z, Yao Q, Lin H, Du X, Zhang K, Han T, Hong W. BMC Med. 2022 Sep 29;20(1):335. doi: 10.1186/s12916-022-02523-w. PubMed |
Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins. Vos DY, Wijers M, Smit M, Huijkman N, Kloosterhuis NJ, Wolters JC, Tissink JJ, Pronk ACM, Kooijman S, Rensen PCN, Kuivenhoven JA, van de Sluis B. Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):e29-e45. doi: 10.1161/ATVBAHA.122.318169. Epub 2022 Nov 10. PubMed |
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease. Wang Z, Zhu S, Jia Y, Wang Y, Kubota N, Fujiwara N, Gordillo R, Lewis C, Zhu M, Sharma T, Li L, Zeng Q, Lin YH, Hsieh MH, Gopal P, Wang T, Hoare M, Campbell P, Hoshida Y, Zhu H. bioRxiv. 2023 Mar 21:2023.03.20.533505. doi: 10.1101/2023.03.20.533505. Preprint. PubMed |
In vivo screening identifies SPP2, a secreted factor that negatively regulates liver regeneration. Lin YH, Zeng Q, Jia Y, Wang Z, Li L, Hsieh MH, Cheng Q, Pagani CA, Livingston N, Lee J, Zhang Y, Sharma T, Siegwart DJ, Yimlamai D, Levi B, Zhu H. Hepatology. 2023 Oct 1;78(4):1133-1148. doi: 10.1097/HEP.0000000000000402. Epub 2023 Apr 12. PubMed |
Adeno-Associated virus 8 delivers an immunomodulatory peptide to mouse liver more efficiently than to rat liver. Wang Y, Hurley A, De Giorgi M, Tanner MR, Hu RC, Pennington MW, Lagor WR, Beeton C. PLoS One. 2023 Apr 11;18(4):e0283996. doi: 10.1371/journal.pone.0283996. eCollection 2023. PubMed |
Adeno-associated virus vector system controlling capsid expression improves viral quantity and quality. Ohba K, Sehara Y, Enoki T, Mineno J, Ozawa K, Mizukami H. iScience. 2023 Mar 23;26(4):106487. doi: 10.1016/j.isci.2023.106487. eCollection 2023 Apr 21. PubMed |
Acute Downregulation but Not Genetic Ablation of Murine MCU Impairs Suppressive Capacity of Regulatory CD4 T Cells. Jost P, Klein F, Brand B, Wahl V, Wyatt A, Yildiz D, Boehm U, Niemeyer BA, Vaeth M, Alansary D. Int J Mol Sci. 2023 Apr 24;24(9):7772. doi: 10.3390/ijms24097772. PubMed |
FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation. Fujinuma S, Nakatsumi H, Shimizu H, Sugiyama S, Harada A, Goya T, Tanaka M, Kohjima M, Takahashi M, Izumi Y, Yagi M, Kang D, Kaneko M, Shigeta M, Bamba T, Ohkawa Y, Nakayama KI. Cell Rep. 2023 May 30;42(5):112530. doi: 10.1016/j.celrep.2023.112530. Epub 2023 May 18. PubMed |
Rational design and experimental evaluation of peptide ligands for the purification of adeno-associated viruses via affinity chromatography. Shastry S, Chu W, Barbieri E, Greback-Clarke P, Smith WK, Cummings C, Minzoni A, Pancorbo J, Gilleskie G, Ritola K, Daniele MA, Johnson TF, Menegatti S. Biotechnol J. 2024 Jan;19(1):e2300230. doi: 10.1002/biot.202300230. Epub 2023 Sep 28. PubMed |
AAV-mediated skeletal muscle specific irisin expression does not contribute to weight loss in mice. Bagon BB, Lee J, Matienzo ME, Lim S, Park JI, Kang S, Kim K, Lee CM, Moon C, Kim DI, Park MJ. Biochem Biophys Res Commun. 2023 Nov 19;682:111-117. doi: 10.1016/j.bbrc.2023.10.004. Epub 2023 Oct 4. PubMed |
Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition. Verkade E, Shen W, Hovingh MV, Mulder NL, de Bruyn K, Koehorst M, de Vries HD, Bloks VW, Kuipers F, de Boer JF. Clin Sci (Lond). 2023 Nov 15;137(21):1637-1650. doi: 10.1042/CS20230812. PubMed |
Daily rhythm in cortical chloride homeostasis underpins functional changes in visual cortex excitability. Pracucci E, Graham RT, Alberio L, Nardi G, Cozzolino O, Pillai V, Pasquini G, Saieva L, Walsh D, Landi S, Zhang J, Trevelyan AJ, Ratto GM. Nat Commun. 2023 Nov 4;14(1):7108. doi: 10.1038/s41467-023-42711-7. PubMed |
Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells. Shao J, Li S, Qiu X, Jiang J, Zhang L, Wang P, Si Y, Wu Y, He M, Xiong Q, Zhao L, Li Y, Fan Y, Viviani M, Fu Y, Wu C, Gao T, Zhu L, Fussenegger M, Wang H, Xie M. Cell Res. 2024 Jan;34(1):31-46. doi: 10.1038/s41422-023-00896-y. Epub 2024 Jan 4. PubMed |
DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER. Rong S, Xia M, Vale G, Wang S, Kim CW, Li S, McDonald JG, Radhakrishnan A, Horton JD. Cell Metab. 2024 Mar 5;36(3):617-629.e7. doi: 10.1016/j.cmet.2024.01.011. Epub 2024 Feb 9. PubMed |
P2Y13 receptor deficiency favors adipose tissue lipolysis and worsens insulin resistance and fatty liver disease. Duparc T, Gore E, Combes G, Beuzelin D, Pires Da Silva J, Bouguetoch V, Marques MA, Velazquez A, Viguerie N, Tavernier G, Arner P, Ryden M, Langin D, Sioufi N, Nasser M, Cabou C, Najib S, Martinez LO. JCI Insight. 2024 Mar 12;9(8):e175623. doi: 10.1172/jci.insight.175623. PubMed |
Rapid in vivo evaluation system for cholestasis-related genes in mice with humanized bile acid profiles. Wakasa K, Tamura R, Osaka S, Takei H, Asai A, Nittono H, Kusuhara H, Hayashi H. Hepatol Commun. 2024 Mar 22;8(4):e0382. doi: 10.1097/HC9.0000000000000382. eCollection 2024 Apr 1. PubMed |
Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins. Stone ML, Lee J, Lee JW, Coho H, Tariveranmoshabad M, Wattenberg MM, Choi H, Herrera VM, Xue Y, Choi-Bose S, Zingone SK, Patel D, Markowitz K, Delman D, Balachandran VP, Beatty GL. Nat Immunol. 2024 May;25(5):755-763. doi: 10.1038/s41590-024-01820-1. Epub 2024 Apr 19. PubMed |
AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model. Willimann M, Tiyaboonchai A, Adachi K, Li B, Waldburger L, Nakai H, Grompe M, Thony B. bioRxiv [Preprint]. 2024 May 29:2024.05.29.596409. doi: 10.1101/2024.05.29.596409. PubMed |
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