pAAV-ABE-NT-sgRNA Citations (3)
Originally described in: Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy.Ryu SM, Koo T, Kim K, Lim K, Baek G, Kim ST, Kim HS, Kim DE, Lee H, Chung E, Kim JS Nat Biotechnol. 2018 Jul;36(6):536-539. doi: 10.1038/nbt.4148. Epub 2018 Apr 27. PubMed Journal
Articles Citing pAAV-ABE-NT-sgRNA
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Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases.
Jang H, Jo DH, Cho CS, Shin JH, Seo JH, Yu G, Gopalappa R, Kim D, Cho SR, Kim JH, Kim HH.
Nat Biomed Eng. 2021 Aug 26. pii: 10.1038/s41551-021-00788-9. doi: 10.1038/s41551-021-00788-9.
PubMed
Associated Plasmids |
| Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice. Whisenant D, Lim K, Revechon G, Yao H, Bergo MO, Machtel P, Kim JS, Eriksson M. Nat Commun. 2022 Jun 2;13(1):3068. doi: 10.1038/s41467-022-30800-y. PubMed |
| In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice. Rovai A, Chung B, Hu Q, Hook S, Yuan Q, Kempf T, Schmidt F, Grimm D, Talbot SR, Steinbruck L, Gotting J, Bohne J, Krooss SA, Ott M. Nat Commun. 2022 Sep 5;13(1):5215. doi: 10.1038/s41467-022-32906-9. PubMed |
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