ppyCAG_RNaseH1_WT Citations (14)
Originally described in: R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters.Chen L, Chen JY, Zhang X, Gu Y, Xiao R, Shao C, Tang P, Qian H, Luo D, Li H, Zhou Y, Zhang DE, Fu XD Mol Cell. 2017 Nov 16;68(4):745-757.e5. doi: 10.1016/j.molcel.2017.10.008. Epub 2017 Nov 2. PubMed Journal
Articles Citing ppyCAG_RNaseH1_WT
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Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency. Sanchez A, de Vivo A, Tonzi P, Kim J, Huang TT, Kee Y. PLoS Genet. 2020 Mar 6;16(3):e1008524. doi: 10.1371/journal.pgen.1008524. eCollection 2020 Mar. PubMed |
DDX5 resolves R-loops at DNA double-strand breaks to promote DNA repair and avoid chromosomal deletions. Yu Z, Mersaoui SY, Guitton-Sert L, Coulombe Y, Song J, Masson JY, Richard S. NAR Cancer. 2020 Sep;2(3):zcaa028. doi: 10.1093/narcan/zcaa028. Epub 2020 Sep 25. PubMed |
CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats. Unoki M, Sharif J, Saito Y, Velasco G, Francastel C, Koseki H, Sasaki H. Sci Rep. 2020 Oct 20;10(1):17865. doi: 10.1038/s41598-020-74636-2. PubMed |
BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage. Vohhodina J, Goehring LJ, Liu B, Kong Q, Botchkarev VV Jr, Huynh M, Liu Z, Abderazzaq FO, Clark AP, Ficarro SB, Marto JA, Hatchi E, Livingston DM. Nat Commun. 2021 Jun 10;12(1):3542. doi: 10.1038/s41467-021-23716-6. PubMed |
Hypoxia-induced SETX links replication stress with the unfolded protein response. Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Nat Commun. 2021 Jun 17;12(1):3686. doi: 10.1038/s41467-021-24066-z. PubMed |
Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1. Nicholas TR, Metcalf SA, Greulich BM, Hollenhorst PC. NAR Cancer. 2021 Aug 14;3(3):zcab033. doi: 10.1093/narcan/zcab033. eCollection 2021 Sep. PubMed |
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer. Guo H, Golczer G, Wittner BS, Langenbucher A, Zachariah M, Dubash TD, Hong X, Comaills V, Burr R, Ebright RY, Horwitz E, Vuille JA, Hajizadeh S, Wiley DF, Reeves BA, Zhang JM, Niederhoffer KL, Lu C, Wesley B, Ho U, Nieman LT, Toner M, Vasudevan S, Zou L, Mostoslavsky R, Maheswaran S, Lawrence MS, Haber DA. Mol Cell. 2021 Oct 7;81(19):4041-4058.e15. doi: 10.1016/j.molcel.2021.09.016. PubMed |
Thrap3 promotes R-loop resolution via interaction with methylated DDX5. Kang HJ, Eom HJ, Kim H, Myung K, Kwon HM, Choi JH. Exp Mol Med. 2021 Oct;53(10):1602-1611. doi: 10.1038/s12276-021-00689-6. Epub 2021 Oct 25. PubMed |
Aberrant R-loop-induced replication stress in MED12-mutant uterine fibroids. Muralimanoharan S, Shamby R, Stansbury N, Schenken R, de la Pena Avalos B, Javanmardi S, Dray E, Sung P, Boyer TG. Sci Rep. 2022 Apr 13;12(1):6169. doi: 10.1038/s41598-022-10188-x. PubMed |
Live-cell imaging unveils distinct R-loop populations with heterogeneous dynamics. Martin RM, de Almeida MR, Gameiro E, de Almeida SF. Nucleic Acids Res. 2023 Nov 10;51(20):11010-11023. doi: 10.1093/nar/gkad812. PubMed |
Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops. Ma TS, Worth KR, Maher C, Ng N, Beghe C, Gromak N, Rose AM, Hammond EM. Nucleic Acids Res. 2023 Nov 27;51(21):11584-11599. doi: 10.1093/nar/gkad858. PubMed |
RTF2 controls replication repriming and ribonucleotide excision at the replisome. Conti BA, Ruiz PD, Broton C, Blobel NJ, Kottemann MC, Sridhar S, Lach FP, Wiley TF, Sasi NK, Carroll T, Smogorzewska A. Nat Commun. 2024 Mar 2;15(1):1943. doi: 10.1038/s41467-024-45947-z. PubMed |
Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS. Duardo RC, Marinello J, Russo M, Morelli S, Pepe S, Guerra F, Gomez-Gonzalez B, Aguilera A, Capranico G. Sci Adv. 2024 May 24;10(21):eadm8196. doi: 10.1126/sciadv.adm8196. Epub 2024 May 24. PubMed |
Dormant origin firing promotes head-on transcription-replication conflicts at transcription termination sites in response to BRCA2 deficiency. Goehring L, Keegan S, Lahiri S, Xia W, Kong M, Jimenez-Sainz J, Gupta D, Drapkin R, Jensen RB, Smith DJ, Rothenberg E, Fenyo D, Huang TT. Nat Commun. 2024 Jun 3;15(1):4716. doi: 10.1038/s41467-024-48286-1. PubMed |
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