ppyCAG_RNaseH1_D210N Citations (11)
Originally described in: R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters.Chen L, Chen JY, Zhang X, Gu Y, Xiao R, Shao C, Tang P, Qian H, Luo D, Li H, Zhou Y, Zhang DE, Fu XD Mol Cell. 2017 Nov 16;68(4):745-757.e5. doi: 10.1016/j.molcel.2017.10.008. Epub 2017 Nov 2. PubMed Journal
Articles Citing ppyCAG_RNaseH1_D210N
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| Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency. Sanchez A, de Vivo A, Tonzi P, Kim J, Huang TT, Kee Y. PLoS Genet. 2020 Mar 6;16(3):e1008524. doi: 10.1371/journal.pgen.1008524. eCollection 2020 Mar. PubMed |
| CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats. Unoki M, Sharif J, Saito Y, Velasco G, Francastel C, Koseki H, Sasaki H. Sci Rep. 2020 Oct 20;10(1):17865. doi: 10.1038/s41598-020-74636-2. PubMed |
Genomic profiling of native R loops with a DNA-RNA hybrid recognition sensor.
Wang K, Wang H, Li C, Yin Z, Xiao R, Li Q, Xiang Y, Wang W, Huang J, Chen L, Fang P, Liang K.
Sci Adv. 2021 Feb 17;7(8). pii: 7/8/eabe3516. doi: 10.1126/sciadv.abe3516. Print 2021 Feb.
PubMed
Associated Plasmids |
| Hypoxia-induced SETX links replication stress with the unfolded protein response. Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Nat Commun. 2021 Jun 17;12(1):3686. doi: 10.1038/s41467-021-24066-z. PubMed |
| HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia. Luo H, Zhu G, Eshelman MA, Fung TK, Lai Q, Wang F, Zeisig BB, Lesperance J, Ma X, Chen S, Cesari N, Cogle C, Chen B, Xu B, Yang FC, So CWE, Qiu Y, Xu M, Huang S. Mol Cell. 2022 Feb 17;82(4):833-851.e11. doi: 10.1016/j.molcel.2022.01.014. PubMed |
| Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation. Leszczynska KB, Dzwigonska M, Estephan H, Moehlenbrink J, Bowler E, Giaccia AJ, Mieczkowski J, Kaminska B, Hammond EM. Mol Oncol. 2023 Jul;17(7):1173-1191. doi: 10.1002/1878-0261.13431. Epub 2023 Apr 22. PubMed |
| APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors. Zong C, Zhang Z, Gao L, He J, Wang Y, Li Q, Liu X, Yang J, Chen D, Huang R, Zheng G, Jin X, Wei W, Jia R, Shen J. Cell Death Dis. 2023 Jun 3;14(6):348. doi: 10.1038/s41419-023-05867-0. PubMed |
| Live-cell imaging unveils distinct R-loop populations with heterogeneous dynamics. Martin RM, de Almeida MR, Gameiro E, de Almeida SF. Nucleic Acids Res. 2023 Nov 10;51(20):11010-11023. doi: 10.1093/nar/gkad812. PubMed |
| Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops. Ma TS, Worth KR, Maher C, Ng N, Beghe C, Gromak N, Rose AM, Hammond EM. Nucleic Acids Res. 2023 Nov 27;51(21):11584-11599. doi: 10.1093/nar/gkad858. PubMed |
| RTF2 controls replication repriming and ribonucleotide excision at the replisome. Conti BA, Ruiz PD, Broton C, Blobel NJ, Kottemann MC, Sridhar S, Lach FP, Wiley TF, Sasi NK, Carroll T, Smogorzewska A. Nat Commun. 2024 Mar 2;15(1):1943. doi: 10.1038/s41467-024-45947-z. PubMed |
| Human DNA topoisomerase I poisoning causes R loop-mediated genome instability attenuated by transcription factor IIS. Duardo RC, Marinello J, Russo M, Morelli S, Pepe S, Guerra F, Gomez-Gonzalez B, Aguilera A, Capranico G. Sci Adv. 2024 May 24;10(21):eadm8196. doi: 10.1126/sciadv.adm8196. Epub 2024 May 24. PubMed |
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