IKK-2 K44M Citations (14)
Originally described in: IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation.Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li J, Young DB, Barbosa M, Mann M, Manning A, Rao A Science. 1997 Oct 31. 278(5339):860-6. PubMed Journal
Articles Citing IKK-2 K44M
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| Muscle precursor cells isolated from aged rats exhibit an increased tumor necrosis factor- alpha response. Lees SJ, Zwetsloot KA, Booth FW. Aging Cell. 2009 Feb;8(1):26-35. doi: 10.1111/j.1474-9726.2008.00445.x. PubMed |
| TBK1-associated protein in endolysosomes (TAPE) is an innate immune regulator modulating the TLR3 and TLR4 signaling pathways. Chang CH, Lai LC, Cheng HC, Chen KR, Syue YZ, Lu HC, Lin WY, Chen SH, Huang HS, Shiau AL, Lei HY, Qin J, Ling P. J Biol Chem. 2011 Mar 4;286(9):7043-51. doi: 10.1074/jbc.M110.164632. Epub 2010 Dec 28. PubMed |
| Lipopolysaccharide enhances transforming growth factor beta1-induced platelet-derived growth factor-B expression in bile duct epithelial cells. Kassel KM, Sullivan BP, Luyendyk JP. J Gastroenterol Hepatol. 2012 Apr;27(4):714-21. doi: 10.1111/j.1440-1746.2011.06941.x. PubMed |
| APPL1 regulates basal NF-kappaB activity by stabilizing NIK. Hupalowska A, Pyrzynska B, Miaczynska M. J Cell Sci. 2012 Sep 1;125(Pt 17):4090-102. doi: 10.1242/jcs.105171. Epub 2012 Jun 8. PubMed |
| Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities. Cocka LJ, Bates P. PLoS Pathog. 2012 Sep;8(9):e1002931. doi: 10.1371/journal.ppat.1002931. Epub 2012 Sep 27. PubMed |
| Fibroblast growth factor homologous factor 1 interacts with NEMO to regulate NF-kappaB signaling in neurons. Konig HG, Fenner BJ, Byrne JC, Schwamborn RF, Bernas T, Jefferies CA, Prehn JH. J Cell Sci. 2012 Dec 15;125(Pt 24):6058-70. doi: 10.1242/jcs.111880. Epub 2012 Oct 24. PubMed |
| The hypoxia-inducible transcription factor ZNF395 is controlled by IkB kinase-signaling and activates genes involved in the innate immune response and cancer. Jordanovski D, Herwartz C, Pawlowski A, Taute S, Frommolt P, Steger G. PLoS One. 2013 Sep 23;8(9):e74911. doi: 10.1371/journal.pone.0074911. eCollection 2013. PubMed |
| Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-kappaB Pathway and Promotes Non-selective Mitophagy. Lim GG, Chua DS, Basil AH, Chan HY, Chai C, Arumugam T, Lim KL. J Biol Chem. 2015 Jul 3;290(27):16882-93. doi: 10.1074/jbc.M114.622399. Epub 2015 May 18. PubMed |
| The ubiquitin ligase HERC3 attenuates NF-kappaB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation. Hochrainer K, Pejanovic N, Olaseun VA, Zhang S, Iadecola C, Anrather J. Nucleic Acids Res. 2015 Nov 16;43(20):9889-904. doi: 10.1093/nar/gkv1064. Epub 2015 Oct 17. PubMed |
| PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-kappaB signaling in lung cancer. Ho MY, Liang CM, Liang SM. Oncotarget. 2016 Aug 9;7(32):52255-52269. doi: 10.18632/oncotarget.10427. PubMed |
| IKKbeta promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3. Reid MA, Lowman XH, Pan M, Tran TQ, Warmoes MO, Ishak Gabra MB, Yang Y, Locasale JW, Kong M. Genes Dev. 2016 Aug 15;30(16):1837-51. doi: 10.1101/gad.287235.116. Epub 2016 Sep 1. PubMed |
| Deletion of IkappaB-Kinase beta in Smooth Muscle Cells Induces Vascular Calcification Through beta-Catenin-Runt-Related Transcription Factor 2 Signaling. Al-Huseini I, Ashida N, Kimura T. J Am Heart Assoc. 2018 Jan 4;7(1). pii: JAHA.117.007405. doi: 10.1161/JAHA.117.007405. PubMed |
| Influenza a virus NS1 resembles a TRAF3-interacting motif to target the RNA sensing-TRAF3-type I IFN axis and impair antiviral innate immunity. Lin CY, Shih MC, Chang HC, Lin KJ, Chen LF, Huang SW, Yang ML, Ma SK, Shiau AL, Wang JR, Chen KR, Ling P. J Biomed Sci. 2021 Oct 5;28(1):66. doi: 10.1186/s12929-021-00764-0. PubMed |
| IKKalpha plays a major role in canonical NF-kappaB signalling in colorectal cells. Prescott JA, Balmanno K, Mitchell JP, Okkenhaug H, Cook SJ. Biochem J. 2022 Feb 11;479(3):305-325. doi: 10.1042/BCJ20210783. PubMed |
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