dCas9-KRAB Citations (7)
Originally described in: An enhanced CRISPR repressor for targeted mammalian gene regulation.Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM Nat Methods. 2018 Jul 16. pii: 10.1038/s41592-018-0048-5. doi: 10.1038/s41592-018-0048-5. PubMed Journal
Articles Citing dCas9-KRAB
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| Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance. Chung JY, Ain QU, Song Y, Yong SB, Kim YH. Genome Res. 2019 Sep;29(9):1442-1452. doi: 10.1101/gr.246900.118. PubMed |
| Transcriptional Inhibition of lncRNA gadd7 by CRISPR/dCas9-KRAB Protects Spermatocyte Viability. Zhao J, Ma W, Zhong Y, Deng H, Zhou B, Wu Y, Yang M, Li H. Front Mol Biosci. 2021 Mar 11;8:652392. doi: 10.3389/fmolb.2021.652392. eCollection 2021. PubMed |
| The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability. Pan Q, Zhong S, Wang H, Wang X, Li N, Li Y, Zhang G, Yuan H, Lian Y, Chen Q, Han Y, Guo J, Liu Q, Qiu T, Jiang J, Li Q, Tan M, Yin H, Peng J, Xiao Y, Qin J. Mol Cell. 2021 Jul 1;81(13):2736-2751.e8. doi: 10.1016/j.molcel.2021.04.009. Epub 2021 Apr 30. PubMed |
| Substrate Stiffness Drives Epithelial to Mesenchymal Transition and Proliferation through the NEAT1-Wnt/beta-Catenin Pathway in Liver Cancer. Xu X, Zhang Y, Wang X, Li S, Tang L. Int J Mol Sci. 2021 Nov 8;22(21). pii: ijms222112066. doi: 10.3390/ijms222112066. PubMed |
An integrated pipeline for mammalian genetic screening.
Kramme C, Plesa AM, Wang HH, Wolf B, Smela MP, Guo X, Kohman RE, Chatterjee P, Church GM.
Cell Rep Methods. 2021 Sep 27;1(6):100082. doi: 10.1016/j.crmeth.2021.100082. eCollection 2021 Oct 25.
PubMed
Associated Plasmids |
| CKM and TERT dual promoters drive CRISPR-dCas9 to specifically inhibit the malignant behavior of osteosarcoma cells. Hu Y, Zhang H, Guo Z, Zhou J, Zhang W, Gong M, Wu J. Cell Mol Biol Lett. 2023 Jul 6;28(1):52. doi: 10.1186/s11658-023-00464-7. PubMed |
| Epigenetic modulation inhibits epithelial-mesenchymal transition-driven fibrogenesis and enhances characteristics of chemically-derived hepatic progenitors. Adisasmita M, Lee HK, An Y, Kim M, Mamo MG, Hur JK, Choi D, Shin JH, Jung YK. Ann Surg Treat Res. 2024 May;106(5):274-283. doi: 10.4174/astr.2024.106.5.274. Epub 2024 Apr 30. PubMed |
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