pXR004: CasRx pre-gRNA cloning backbone Citations (10)
Originally described in: Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.Konermann S, Lotfy P, Brideau NJ, Oki J, Shokhirev MN, Hsu PD Cell. 2018 Mar 8. pii: S0092-8674(18)30207-1. doi: 10.1016/j.cell.2018.02.033. PubMed Journal
Articles Citing pXR004: CasRx pre-gRNA cloning backbone
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Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza.
Abbott TR, Dhamdhere G, Liu Y, Lin X, Goudy L, Zeng L, Chemparathy A, Chmura S, Heaton NS, Debs R, Pande T, Endy D, La Russa MF, Lewis DB, Qi LS.
Cell. 2020 May 14;181(4):865-876.e12. doi: 10.1016/j.cell.2020.04.020. Epub 2020 Apr 29.
PubMed
Associated Plasmids |
CRISPR-assisted detection of RNA-protein interactions in living cells.
Yi W, Li J, Zhu X, Wang X, Fan L, Sun W, Liao L, Zhang J, Li X, Ye J, Chen F, Taipale J, Chan KM, Zhang L, Yan J.
Nat Methods. 2020 Jun 22. pii: 10.1038/s41592-020-0866-0. doi: 10.1038/s41592-020-0866-0.
PubMed
Associated Plasmids |
| Optimized RNA-targeting CRISPR/Cas13d technology outperforms shRNA in identifying functional circRNAs. Zhang Y, Nguyen TM, Zhang XO, Wang L, Phan T, Clohessy JG, Pandolfi PP. Genome Biol. 2021 Jan 21;22(1):41. doi: 10.1186/s13059-021-02263-9. PubMed |
| A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses. Lin X, Liu Y, Chemparathy A, Pande T, La Russa M, Qi LS. Cell Rep Med. 2021 Apr 20;2(4):100245. doi: 10.1016/j.xcrm.2021.100245. Epub 2021 Mar 23. PubMed |
| CRISPR/Cas13d-mediated efficient KDM5B mRNA knockdown in porcine somatic cells and parthenogenetic embryos. Bi D, Yao J, Wang Y, Qin G, Zhang Y, Wang Y, Zhao J. Reproduction. 2021 Jul 8;162(2):149-160. doi: 10.1530/REP-21-0053. PubMed |
Methods for in vitro CRISPR/CasRx-Mediated RNA Editing.
Chuang YF, Wang PY, Kumar S, Lama S, Lin FL, Liu GS.
Front Cell Dev Biol. 2021 Jun 11;9:667879. doi: 10.3389/fcell.2021.667879. eCollection 2021.
PubMed
Associated Plasmids |
| Efficient Inhibition of HIV Using CRISPR/Cas13d Nuclease System. Nguyen H, Wilson H, Jayakumar S, Kulkarni V, Kulkarni S. Viruses. 2021 Sep 16;13(9). pii: v13091850. doi: 10.3390/v13091850. PubMed |
| Miat and interacting protein Metadherin maintain a stem-like niche to promote medulloblastoma tumorigenesis and treatment resistance. Peng KL, Vasudevan HN, Lockney DT, Baum R, Hendrickson RC, Raleigh DR, Schmitt AM. Proc Natl Acad Sci U S A. 2022 Sep 13;119(37):e2203738119. doi: 10.1073/pnas.2203738119. Epub 2022 Sep 6. PubMed |
| CRISPR-Cas13d effectively targets SARS-CoV-2 variants, including Delta and Omicron, and inhibits viral infection. Liu Z, Gao X, Kan C, Li L, Zhang Y, Gao Y, Zhang S, Zhou L, Zhao H, Li M, Zhang Z, Sun Y. MedComm (2020). 2023 Jan 31;4(1):e208. doi: 10.1002/mco2.208. eCollection 2023 Feb. PubMed |
| TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation. Suzuki MM, Iijima K, Ogami K, Shinjo K, Murofushi Y, Xie J, Wang X, Kitano Y, Mamiya A, Kibe Y, Nishimura T, Ohka F, Saito R, Sato S, Kobayashi J, Yao R, Miyata K, Kataoka K, Suzuki HI, Kondo Y. Nat Commun. 2023 Aug 22;14(1):4521. doi: 10.1038/s41467-023-40243-8. PubMed |
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