pXR002: EF1a-dCasRx-2A-EGFP Citations (16)
Originally described in: Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.Konermann S, Lotfy P, Brideau NJ, Oki J, Shokhirev MN, Hsu PD Cell. 2018 Mar 8. pii: S0092-8674(18)30207-1. doi: 10.1016/j.cell.2018.02.033. PubMed Journal
Articles Citing pXR002: EF1a-dCasRx-2A-EGFP
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| Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d. Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D. Cell. 2018 Sep 20;175(1):212-223.e17. doi: 10.1016/j.cell.2018.09.001. PubMed |
| CRISPR-Cas13d mediates robust RNA virus interference in plants. Mahas A, Aman R, Mahfouz M. Genome Biol. 2019 Dec 2;20(1):263. doi: 10.1186/s13059-019-1881-2. PubMed |
CRISPR-assisted detection of RNA-protein interactions in living cells.
Yi W, Li J, Zhu X, Wang X, Fan L, Sun W, Liao L, Zhang J, Li X, Ye J, Chen F, Taipale J, Chan KM, Zhang L, Yan J.
Nat Methods. 2020 Jun 22. pii: 10.1038/s41592-020-0866-0. doi: 10.1038/s41592-020-0866-0.
PubMed
Associated Plasmids |
| RNA m(6)A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability. Xiong F, Wang R, Lee JH, Li S, Chen SF, Liao Z, Hasani LA, Nguyen PT, Zhu X, Krakowiak J, Lee DF, Han L, Tsai KL, Liu Y, Li W. Cell Res. 2021 Aug;31(8):861-885. doi: 10.1038/s41422-021-00515-8. Epub 2021 Jun 9. PubMed |
| Efficient Inhibition of HIV Using CRISPR/Cas13d Nuclease System. Nguyen H, Wilson H, Jayakumar S, Kulkarni V, Kulkarni S. Viruses. 2021 Sep 16;13(9). pii: v13091850. doi: 10.3390/v13091850. PubMed |
| Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex. Han C, Sun LY, Luo XQ, Pan Q, Sun YM, Zeng ZC, Chen TQ, Huang W, Fang K, Wang WT, Chen YQ. Cell Rep. 2022 Mar 29;38(13):110421. doi: 10.1016/j.celrep.2022.110421. PubMed |
| Negative autoregulation mitigates collateral RNase activity of repeat-targeting CRISPR-Cas13d in mammalian cells. Kelley CP, Haerle MC, Wang ET. Cell Rep. 2022 Aug 16;40(7):111226. doi: 10.1016/j.celrep.2022.111226. PubMed |
| A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells. Porman AM, Roberts JT, Duncan ED, Chrupcala ML, Levine AA, Kennedy MA, Williams MM, Richer JK, Johnson AM. PLoS Biol. 2022 Nov 28;20(11):e3001885. doi: 10.1371/journal.pbio.3001885. eCollection 2022 Nov. PubMed |
| METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL. Wu Y, Jin M, Fernandez M, Hart KL, Liao A, Ge X, Fernandes SM, McDonald T, Chen Z, Roth D, Ghoda LY, Marcucci G, Kalkum M, Pillai RK, Danilov AV, Li JJ, Chen J, Brown JR, Rosen ST, Siddiqi T, Wang L. Blood Cancer Discov. 2023 May 1;4(3):228-245. doi: 10.1158/2643-3230.BCD-22-0156. PubMed |
| Deep screening of proximal and distal splicing-regulatory elements in a native sequence context. Recinos Y, Ustianenko D, Yeh YT, Wang X, Jacko M, Yesantharao LV, Wu Q, Zhang C. bioRxiv [Preprint]. 2023 Aug 21:2023.08.21.554109. doi: 10.1101/2023.08.21.554109. PubMed |
| Noncoding function of super enhancer derived mRNA in modulating neighboring gene expression and TAD interaction. Xie B, Dean A. bioRxiv [Preprint]. 2023 Dec 5:2023.12.05.570115. doi: 10.1101/2023.12.05.570115. PubMed |
| Programmable RNA 5-methylcytosine (m5C) modification of cellular RNAs by dCasRx conjugated methyltransferase and demethylase. Zhang T, Zhao F, Li J, Sun X, Zhang X, Wang H, Fan P, Lai L, Li Z, Sui T. Nucleic Acids Res. 2024 Apr 12;52(6):2776-2791. doi: 10.1093/nar/gkae110. PubMed |
| dCas13-mediated translational repression for accurate gene silencing in mammalian cells. Apostolopoulos A, Kawamoto N, Chow SYA, Tsuiji H, Ikeuchi Y, Shichino Y, Iwasaki S. Nat Commun. 2024 Mar 11;15(1):2205. doi: 10.1038/s41467-024-46412-7. PubMed |
| Engineering a synthetic gene circuit for high-performance inducible expression in mammalian systems. De Carluccio G, Fusco V, di Bernardo D. Nat Commun. 2024 Apr 17;15(1):3311. doi: 10.1038/s41467-024-47592-y. PubMed |
CRISPR-dCas13d-based deep screening of proximal and distal splicing-regulatory elements.
Recinos Y, Ustianenko D, Yeh YT, Wang X, Jacko M, Yesantharao LV, Wu Q, Zhang C.
Nat Commun. 2024 May 7;15(1):3839. doi: 10.1038/s41467-024-47140-8.
PubMed
Associated Plasmids |
| Lineage-specific splicing regulation of MAPT gene in the primate brain. Recinos Y, Bao S, Wang X, Phillips BL, Yeh YT, Weyn-Vanhentenryck SM, Swanson MS, Zhang C. Cell Genom. 2024 Jun 12;4(6):100563. doi: 10.1016/j.xgen.2024.100563. Epub 2024 May 20. PubMed |
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