pLKO.1 - TRC control Citations (144)
Originally described in: A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE Cell. 2006 Mar 24. 124(6):1283-98. PubMed Journal
Articles Citing pLKO.1 - TRC control
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| pVHL and GSK3beta are components of a primary cilium-maintenance signalling network. Thoma CR, Frew IJ, Hoerner CR, Montani M, Moch H, Krek W. Nat Cell Biol. 2007 May . 9(5):588-95. PubMed |
| Formation of Kv2.1-FAK complex as a mechanism of FAK activation, cell polarization and enhanced motility. Wei JF, Wei L, Zhou X, Lu ZY, Francis K, Hu XY, Liu Y, Xiong WC, Zhang X, Banik NL, Zheng SS, Yu SP. J Cell Physiol. 2008 Nov;217(2):544-57. doi: 10.1002/jcp.21530. PubMed |
| Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis. Pendino F, Nguyen E, Jonassen I, Dysvik B, Azouz A, Lanotte M, Segal-Bendirdjian E, Lillehaug JR. Blood. 2009 Apr 2;113(14):3172-81. doi: 10.1182/blood-2008-07-170035. Epub 2009 Jan 30. PubMed |
| Transforming growth-interacting factor (TGIF) regulates proliferation and differentiation of human myeloid leukemia cells. Hamid R, Brandt SJ. Mol Oncol. 2009 Dec;3(5-6):451-63. doi: 10.1016/j.molonc.2009.07.004. Epub 2009 Jul 29. PubMed |
| Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain shedding. Muck C, Herndler-Brandstetter D, Micutkova L, Grubeck-Loebenstein B, Jansen-Durr P. J Gerontol A Biol Sci Med Sci. 2010 Nov;65(11):1165-80. doi: 10.1093/gerona/glq129. Epub 2010 Jul 30. PubMed |
| Adenovirus membrane penetration activates the NLRP3 inflammasome. Barlan AU, Griffin TM, McGuire KA, Wiethoff CM. J Virol. 2011 Jan;85(1):146-55. doi: 10.1128/JVI.01265-10. Epub 2010 Oct 27. PubMed |
| Hypoxic preconditioning enhances bone marrow mesenchymal stem cell migration via Kv2.1 channel and FAK activation. Hu X, Wei L, Taylor TM, Wei J, Zhou X, Wang JA, Yu SP. Am J Physiol Cell Physiol. 2011 Aug;301(2):C362-72. doi: 10.1152/ajpcell.00013.2010. Epub 2011 May 11. PubMed |
| Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species. McGuire KA, Barlan AU, Griffin TM, Wiethoff CM. J Virol. 2011 Oct;85(20):10806-13. doi: 10.1128/JVI.00675-11. Epub 2011 Aug 10. PubMed |
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.
Kofoed EM, Vance RE.
Nature. 2011 Aug 28;477(7366):592-5. doi: 10.1038/nature10394.
PubMed
Associated Plasmids |
| Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. Pircher H, Straganz GD, Ehehalt D, Morrow G, Tanguay RM, Jansen-Durr P. J Biol Chem. 2011 Oct 21;286(42):36500-8. doi: 10.1074/jbc.M111.264770. Epub 2011 Aug 30. PubMed |
| Carbonic anhydrase III regulates peroxisome proliferator-activated receptor-gamma2. Mitterberger MC, Kim G, Rostek U, Levine RL, Zwerschke W. Exp Cell Res. 2012 May 1;318(8):877-86. doi: 10.1016/j.yexcr.2012.02.011. Epub 2012 Feb 28. PubMed |
| DLK1(PREF1) is a negative regulator of adipogenesis in CD105(+)/CD90(+)/CD34(+)/CD31(-)/FABP4(-) adipose-derived stromal cells from subcutaneous abdominal fat pats of adult women. Mitterberger MC, Lechner S, Mattesich M, Kaiser A, Probst D, Wenger N, Pierer G, Zwerschke W. Stem Cell Res. 2012 Jul;9(1):35-48. doi: 10.1016/j.scr.2012.04.001. Epub 2012 Apr 17. PubMed |
| Adenovirus delivered short hairpin RNA targeting a conserved site in the 5' non-translated region inhibits all four serotypes of dengue viruses. Korrapati AB, Swaminathan G, Singh A, Khanna N, Swaminathan S. PLoS Negl Trop Dis. 2012;6(7):e1735. doi: 10.1371/journal.pntd.0001735. Epub 2012 Jul 24. PubMed |
| Loss of PBRM1 expression is associated with renal cell carcinoma progression. Pawlowski R, Muhl SM, Sulser T, Krek W, Moch H, Schraml P. Int J Cancer. 2013 Jan 15;132(2):E11-7. doi: 10.1002/ijc.27822. Epub 2012 Oct 3. PubMed |
| Microtubule plus-end tracking protein CLASP2 regulates neuronal polarity and synaptic function. Beffert U, Dillon GM, Sullivan JM, Stuart CE, Gilbert JP, Kambouris JA, Ho A. J Neurosci. 2012 Oct 3;32(40):13906-16. doi: 10.1523/JNEUROSCI.2108-12.2012. PubMed |
| Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts. Gagan J, Dey BK, Layer R, Yan Z, Dutta A. J Biol Chem. 2012 Nov 23;287(48):40360-70. doi: 10.1074/jbc.M112.378414. Epub 2012 Oct 10. PubMed |
| Silencing alpha1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion. Buffone A Jr, Mondal N, Gupta R, McHugh KP, Lau JT, Neelamegham S. J Biol Chem. 2013 Jan 18;288(3):1620-33. doi: 10.1074/jbc.M112.400929. Epub 2012 Nov 28. PubMed |
| Role of C/EBPbeta-LAP and C/EBPbeta-LIP in early adipogenic differentiation of human white adipose-derived progenitors and at later stages in immature adipocytes. Lechner S, Mitterberger MC, Mattesich M, Zwerschke W. Differentiation. 2013 Jan;85(1-2):20-31. doi: 10.1016/j.diff.2012.11.001. Epub 2013 Jan 11. PubMed |
| NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Chang CY, Pasolli HA, Giannopoulou EG, Guasch G, Gronostajski RM, Elemento O, Fuchs E. Nature. 2013 Mar 7;495(7439):98-102. doi: 10.1038/nature11847. Epub 2013 Feb 6. PubMed |
| PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1alpha expression and protein stability. Liu Y, Zhang JB, Qin Y, Wang W, Wei L, Teng Y, Guo L, Zhang B, Lin Z, Liu J, Ren ZG, Ye QH, Xie Y. Hepatology. 2013 Aug;58(2):692-705. doi: 10.1002/hep.26398. PubMed |
| The ULb' region of the human cytomegalovirus genome confers an increased requirement for the viral protein kinase UL97. Wang D, Li G, Schauflinger M, Nguyen CC, Hall ED, Yurochko AD, von Einem J, Kamil JP. J Virol. 2013 Jun;87(11):6359-76. doi: 10.1128/JVI.03477-12. Epub 2013 Mar 27. PubMed |
| Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice. Albers J, Rajski M, Schonenberger D, Harlander S, Schraml P, von Teichman A, Georgiev S, Wild PJ, Moch H, Krek W, Frew IJ. EMBO Mol Med. 2013 Jun;5(6):949-64. doi: 10.1002/emmm.201202231. Epub 2013 Apr 22. PubMed |
| Prox1 directly interacts with LSD1 and recruits the LSD1/NuRD complex to epigenetically co-repress CYP7A1 transcription. Ouyang H, Qin Y, Liu Y, Xie Y, Liu J. PLoS One. 2013 Apr 23;8(4):e62192. doi: 10.1371/journal.pone.0062192. Print 2013. PubMed |
| Efficacious proteasome/HDAC inhibitor combination therapy for primary effusion lymphoma. Bhatt S, Ashlock BM, Toomey NL, Diaz LA, Mesri EA, Lossos IS, Ramos JC. J Clin Invest. 2013 Jun;123(6):2616-28. doi: 10.1172/JCI64503. Epub 2013 May 1. PubMed |
| An isoform of C/EBPbeta, LIP, regulates expression of the chemokine receptor CXCR4 and modulates breast cancer cell migration. Park BH, Kook S, Lee S, Jeong JH, Brufsky A, Lee BC. J Biol Chem. 2013 Oct 4;288(40):28656-67. doi: 10.1074/jbc.M113.509505. Epub 2013 Aug 21. PubMed |
| Androgen receptor is negatively correlated with the methylation-mediated transcriptional repression of miR-375 in human prostate cancer cells. Chu M, Chang Y, Li P, Guo Y, Zhang K, Gao W. Oncol Rep. 2014 Jan;31(1):34-40. doi: 10.3892/or.2013.2810. Epub 2013 Oct 24. PubMed |
| Plakoglobin but not desmoplakin regulates keratinocyte cohesion via modulation of p38MAPK signaling. Spindler V, Dehner C, Hubner S, Waschke J. J Invest Dermatol. 2014 Jun;134(6):1655-64. doi: 10.1038/jid.2014.21. Epub 2014 Jan 17. PubMed |
| Pancreatic cancer counterattack: MUC4 mediates Fas-independent apoptosis of antigen-specific cytotoxic T lymphocyte. Zhu Y, Zhang JJ, Liang WB, Zhu R, Wang B, Miao Y, Xu ZK. Oncol Rep. 2014 Apr;31(4):1768-76. doi: 10.3892/or.2014.3016. Epub 2014 Feb 10. PubMed |
| RIP1 maintains DNA integrity and cell proliferation by regulating PGC-1alpha-mediated mitochondrial oxidative phosphorylation and glycolysis. Chen W, Wang Q, Bai L, Chen W, Wang X, Tellez CS, Leng S, Padilla MT, Nyunoya T, Belinsky SA, Lin Y. Cell Death Differ. 2014 Jul;21(7):1061-70. doi: 10.1038/cdd.2014.25. Epub 2014 Feb 28. PubMed |
| CDK2-dependent phosphorylation of Suv39H1 is involved in control of heterochromatin replication during cell cycle progression. Park SH, Yu SE, Chai YG, Jang YK. Nucleic Acids Res. 2014 Jun;42(10):6196-207. doi: 10.1093/nar/gku263. Epub 2014 Apr 11. PubMed |
| Evaluation of apoptosis induction by concomitant inhibition of MEK, mTOR, and Bcl-2 in human acute myelogenous leukemia cells. Zhang W, Ruvolo VR, Gao C, Zhou L, Bornmann W, Tsao T, Schober WD, Smith P, Guichard S, Konopleva M, Andreeff M. Mol Cancer Ther. 2014 Jul;13(7):1848-59. doi: 10.1158/1535-7163.MCT-13-0576. Epub 2014 Apr 16. PubMed |
| MST4 promotes hepatocellular carcinoma epithelial-mesenchymal transition and metastasis via activation of the p-ERK pathway. Lin ZH, Wang L, Zhang JB, Liu Y, Li XQ, Guo L, Zhang B, Zhu WW, Ye QH. Int J Oncol. 2014 Aug;45(2):629-40. doi: 10.3892/ijo.2014.2455. Epub 2014 May 22. PubMed |
| Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma. Lakhter AJ, Hamilton J, Dagher PC, Mukkamala S, Hato T, Dong XC, Mayo LD, Harris RA, Shekhar A, Ivan M, Brustovetsky N, Naidu SR. Oncotarget. 2014 Dec 30;5(24):12694-703. PubMed |
| Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation. Bruserud O, Reikvam H, Fredly H, Skavland J, Hagen KM, van Hoang TT, Brenner AK, Kadi A, Astori A, Gjertsen BT, Pendino F. Oncotarget. 2015 Feb 20;6(5):2794-811. PubMed |
| UBE3C promotes growth and metastasis of renal cell carcinoma via activating Wnt/beta-catenin pathway. Wen JL, Wen XF, Li RB, Jin YC, Wang XL, Zhou L, Chen HX. PLoS One. 2015 Feb 6;10(2):e0115622. doi: 10.1371/journal.pone.0115622. eCollection 2015. PubMed |
| PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing beta-catenin expression and nuclear translocation. Liu Y, Ye X, Zhang JB, Ouyang H, Shen Z, Wu Y, Wang W, Wu J, Tao S, Yang X, Qiao K, Zhang J, Liu J, Fu Q, Xie Y. Oncogene. 2015 Feb 16. doi: 10.1038/onc.2015.7. PubMed |
| Role of cortactin homolog HS1 in transendothelial migration of natural killer cells. Mukherjee S, Kim J, Mooren OL, Shahan ST, Cohan M, Cooper JA. PLoS One. 2015 Feb 27;10(2):e0118153. doi: 10.1371/journal.pone.0118153. eCollection 2015. PubMed |
| The histone acetyltransferase Myst2 regulates Nanog expression, and is involved in maintaining pluripotency and self-renewal of embryonic stem cells. Kim MS, Cho HI, Park SH, Kim JH, Chai YG, Jang YK. FEBS Lett. 2015 Apr 2;589(8):941-50. doi: 10.1016/j.febslet.2015.02.029. Epub 2015 Mar 3. PubMed |
| Role of EGFR expression levels in the regulation of integrin function by EGF. Vial D, McKeown-Longo PJ. Mol Carcinog. 2015 Jun 4. doi: 10.1002/mc.22346. PubMed |
| cAMP-Dependent Protein Kinase A (PKA)-Mediated c-Myc Degradation Is Dependent on the Relative Proportion of PKA-I and PKA-II Isozymes. Liu Q, Nguyen E, Doskeland S, Segal-Bendirdjian E. Mol Pharmacol. 2015 Sep;88(3):469-76. doi: 10.1124/mol.115.097915. Epub 2015 Jun 23. PubMed |
| Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells. Ruvolo PP, Ruvolo VR, Benton CB, AlRawi A, Burks JK, Schober W, Rolke J, Tidmarsh G, Hail N Jr, Eric Davis R, Andreeff M. Biochim Biophys Acta. 2015 Dec 17;1863(4):562-571. doi: 10.1016/j.bbamcr.2015.12.008. PubMed |
| Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease. Menezes LF, Lin CC, Zhou F, Germino GG. EBioMedicine. 2016 Jan 26;5:183-92. doi: 10.1016/j.ebiom.2016.01.027. eCollection 2016 Mar. PubMed |
| HDAC inhibitors cause site-specific chromatin remodeling at PU.1-bound enhancers in K562 cells. Frank CL, Manandhar D, Gordan R, Crawford GE. Epigenetics Chromatin. 2016 Apr 16;9:15. doi: 10.1186/s13072-016-0065-5. eCollection 2016. PubMed |
Optogenetic toolkit reveals the role of Ca2+ sparklets in coordinated cell migration.
Kim JM, Lee M, Kim N, Heo WD.
Proc Natl Acad Sci U S A. 2016 May 24;113(21):5952-7. doi: 10.1073/pnas.1518412113. Epub 2016 May 17.
PubMed
Associated Plasmids |
| The BRPF2/BRD1-MOZ complex is involved in retinoic acid-induced differentiation of embryonic stem cells. Cho HI, Kim MS, Jang YK. Exp Cell Res. 2016 May 30. pii: S0014-4827(16)30140-9. doi: 10.1016/j.yexcr.2016.05.022. PubMed |
| LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer. Sas-Chen A, Aure MR, Leibovich L, Carvalho S, Enuka Y, Korner C, Polycarpou-Schwarz M, Lavi S, Nevo N, Kuznetsov Y, Yuan J, Azuaje F, Ulitsky I, Diederichs S, Wiemann S, Yakhini Z, Kristensen VN, Borresen-Dale AL, Yarden Y. EMBO Mol Med. 2016 Sep 1;8(9):1052-64. doi: 10.15252/emmm.201606198. PubMed |
| Nuclear factor Y regulates ancient budgerigar hepadnavirus core promoter activity. Shen Z, Liu Y, Luo M, Wang W, Liu J, Liu W, Pan S, Xie Y. Biochem Biophys Res Commun. 2016 Sep 16;478(2):825-30. doi: 10.1016/j.bbrc.2016.08.032. Epub 2016 Aug 5. PubMed |
| Regulation of Neuronal Survival by Nucleophosmin 1 (NPM1) Is Dependent on Its Expression Level, Subcellular Localization, and Oligomerization Status. Pfister JA, D'Mello SR. J Biol Chem. 2016 Sep 23;291(39):20787-97. doi: 10.1074/jbc.M116.723015. Epub 2016 Aug 10. PubMed |
| Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth. Lakhter AJ, Hamilton J, Konger RL, Brustovetsky N, Broxmeyer HE, Naidu SR. J Biol Chem. 2016 Oct 14;291(42):21869-21879. Epub 2016 Aug 18. PubMed |
Normalizing translation through 4E-BP prevents mTOR-driven cortical mislamination and ameliorates aberrant neuron integration.
Lin TV, Hsieh L, Kimura T, Malone TJ, Bordey A.
Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11330-11335. Epub 2016 Sep 19.
PubMed
Associated Plasmids |
| Gene expression elucidates functional impact of polygenic risk for schizophrenia. Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gumus ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF, Wang YC, Mahajan MC, Derry JM, Dudley JT, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn CG, Lewis DA, Haroutunian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hirai K, Roeder K, Brennand KJ, Katsanis N, Domenici E, Devlin B, Sklar P. Nat Neurosci. 2016 Nov;19(11):1442-1453. doi: 10.1038/nn.4399. Epub 2016 Sep 26. PubMed |
| Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer. Ni T, Li XY, Lu N, An T, Liu ZP, Fu R, Lv WC, Zhang YW, Xu XJ, Grant Rowe R, Lin YS, Scherer A, Feinberg T, Zheng XQ, Chen BA, Liu XS, Guo QL, Wu ZQ, Weiss SJ. Nat Cell Biol. 2016 Nov;18(11):1221-1232. doi: 10.1038/ncb3425. Epub 2016 Oct 17. PubMed |
| Vasculogenic mimicry in small cell lung cancer. Williamson SC, Metcalf RL, Trapani F, Mohan S, Antonello J, Abbott B, Leong HS, Chester CP, Simms N, Polanski R, Nonaka D, Priest L, Fusi A, Carlsson F, Carlsson A, Hendrix MJ, Seftor RE, Seftor EA, Rothwell DG, Hughes A, Hicks J, Miller C, Kuhn P, Brady G, Simpson KL, Blackhall FH, Dive C. Nat Commun. 2016 Nov 9;7:13322. doi: 10.1038/ncomms13322. PubMed |
| NRL-Regulated Transcriptome Dynamics of Developing Rod Photoreceptors. Kim JW, Yang HJ, Brooks MJ, Zelinger L, Karakulah G, Gotoh N, Boleda A, Gieser L, Giuste F, Whitaker DT, Walton A, Villasmil R, Barb JJ, Munson PJ, Kaya KD, Chaitankar V, Cogliati T, Swaroop A. Cell Rep. 2016 Nov 22;17(9):2460-2473. doi: 10.1016/j.celrep.2016.10.074. PubMed |
| OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKCdelta/p53. Omar HA, Tolba MF, Hung JH, Al-Tel TH. Front Pharmacol. 2016 Nov 30;7:463. eCollection 2016. PubMed |
| Targeting metastasis-initiating cells through the fatty acid receptor CD36. Pascual G, Avgustinova A, Mejetta S, Martin M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescos C, Di Croce L, Benitah SA. Nature. 2017 Jan 5;541(7635):41-45. doi: 10.1038/nature20791. Epub 2016 Dec 7. PubMed |
| Focal Adhesion Kinase as a Potential Target in AML and MDS. Carter BZ, Mak PY, Wang X, Yang H, Garcia-Manero G, Mak DH, Mu H, Ruvolo VR, Qiu Y, Coombes K, Zhang N, Ragon B, Weaver DT, Pachter JA, Kornblau S, Andreeff M. Mol Cancer Ther. 2017 Jun;16(6):1133-1144. doi: 10.1158/1535-7163.MCT-16-0719. Epub 2017 Mar 7. PubMed |
| CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Dillon GM, Tyler WA, Omuro KC, Kambouris J, Tyminski C, Henry S, Haydar TF, Beffert U, Ho A. Neuron. 2017 Mar 22;93(6):1344-1358.e5. doi: 10.1016/j.neuron.2017.02.039. Epub 2017 Mar 9. PubMed |
| Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells. Petit M, Koziel R, Etemad S, Pircher H, Jansen-Durr P. Exp Gerontol. 2017 Jun;92:7-12. doi: 10.1016/j.exger.2017.03.004. Epub 2017 Mar 8. PubMed |
| Hepatocyte nuclear factor 1alpha downregulates HBV gene expression and replication by activating the NF-kappaB signaling pathway. Lin J, Gu C, Shen Z, Liu Y, Wang W, Tao S, Cui X, Liu J, Xie Y. PLoS One. 2017 Mar 20;12(3):e0174017. doi: 10.1371/journal.pone.0174017. eCollection 2017. PubMed |
| GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation. Zhang X, Zhu C, Wang T, Jiang H, Ren Y, Zhang Q, Wu K, Liu F, Liu Y, Wu J. PLoS Pathog. 2017 Apr 10;13(4):e1006321. doi: 10.1371/journal.ppat.1006321. eCollection 2017 Apr. PubMed |
| Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease. Louis Sam Titus ASC, Yusuff T, Cassar M, Thomas E, Kretzschmar D, D'Mello SR. J Neurosci. 2017 Jul 5;37(27):6575-6587. doi: 10.1523/JNEUROSCI.3612-16.2017. Epub 2017 May 26. PubMed |
| Prospero-related homeobox 1 drives angiogenesis of hepatocellular carcinoma through selectively activating interleukin-8 expression. Liu Y, Zhang Y, Wang S, Dong QZ, Shen Z, Wang W, Tao S, Gu C, Liu J, Xie Y, Qin LX. Hepatology. 2017 Dec;66(6):1894-1909. doi: 10.1002/hep.29337. PubMed |
| A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation. Wu SJ, Niknafs YS, Kim SH, Oravecz-Wilson K, Zajac C, Toubai T, Sun Y, Prasad J, Peltier D, Fujiwara H, Hedig I, Mathewson ND, Khoriaty R, Ginsburg D, Reddy P. Cell Rep. 2017 Jun 27;19(13):2645-2656. doi: 10.1016/j.celrep.2017.06.013. PubMed |
| Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP. Zhang D, Yang S, Toledo EM, Gyllborg D, Salto C, Carlos Villaescusa J, Arenas E. Sci Signal. 2017 Aug 22;10(493). pii: 10/493/eaal4165. doi: 10.1126/scisignal.aal4165. PubMed |
| Effects of Ferroportin-Mediated Iron Depletion in Cells Representative of Different Histological Subtypes of Prostate Cancer. Deng Z, Manz DH, Torti SV, Torti FM. Antioxid Redox Signal. 2019 Mar 10;30(8):1043-1061. doi: 10.1089/ars.2017.7023. Epub 2017 Dec 11. PubMed |
| TGF-beta-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma. Brown JA, Yonekubo Y, Hanson N, Sastre-Perona A, Basin A, Rytlewski JA, Dolgalev I, Meehan S, Tsirigos A, Beronja S, Schober M. Cell Stem Cell. 2017 Nov 2;21(5):650-664.e8. doi: 10.1016/j.stem.2017.10.001. PubMed |
| Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution. Fei J, Jadaliha M, Harmon TS, Li ITS, Hua B, Hao Q, Holehouse AS, Reyer M, Sun Q, Freier SM, Pappu RV, Prasanth KV, Ha T. J Cell Sci. 2017 Dec 15;130(24):4180-4192. doi: 10.1242/jcs.206854. Epub 2017 Nov 13. PubMed |
| Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth. Deng Z, Manz DH, Torti SV, Torti FM. Oncotarget. 2017 Jul 17;8(47):82231-82243. doi: 10.18632/oncotarget.19288. eCollection 2017 Oct 10. PubMed |
| Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy. Pan R, Ruvolo V, Mu H, Leverson JD, Nichols G, Reed JC, Konopleva M, Andreeff M. Cancer Cell. 2017 Dec 11;32(6):748-760.e6. doi: 10.1016/j.ccell.2017.11.003. PubMed |
| Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells. Lee J, Kim MS, Park SH, Jang YK. Sci Rep. 2018 Jan 10;8(1):334. doi: 10.1038/s41598-017-18628-9. PubMed |
| Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection. Johnson JS, Lucas SY, Amon LM, Skelton S, Nazitto R, Carbonetti S, Sather DN, Littman DR, Aderem A. Cell Host Microbe. 2018 Mar 14;23(3):366-381.e9. doi: 10.1016/j.chom.2018.01.012. PubMed |
| Yes-associated protein mediates human embryonic stem cell-derived cardiomyocyte proliferation: Involvement of epidermal growth factor receptor signaling. Park S, Choe M, Yeo H, Han H, Kim J, Chang W, Yun S, Lee H, Lee M. J Cell Physiol. 2018 Oct;233(10):7016-7025. doi: 10.1002/jcp.26625. Epub 2018 Apr 25. PubMed |
| Targeted Enhancer Activation by a Subunit of the Integrator Complex. Barbieri E, Trizzino M, Welsh SA, Owens TA, Calabretta B, Carroll M, Sarma K, Gardini A. Mol Cell. 2018 Jul 5;71(1):103-116.e7. doi: 10.1016/j.molcel.2018.05.031. Epub 2018 Jun 28. PubMed |
| LncRNA MIR100HG promotes cell proliferation in triple-negative breast cancer through triplex formation with p27 loci. Wang S, Ke H, Zhang H, Ma Y, Ao L, Zou L, Yang Q, Zhu H, Nie J, Wu C, Jiao B. Cell Death Dis. 2018 Jul 24;9(8):805. doi: 10.1038/s41419-018-0869-2. PubMed |
| A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Piragyte I, Clapes T, Polyzou A, Klein Geltink RI, Lefkopoulos S, Yin N, Cauchy P, Curtis JD, Klaeyle L, Langa X, Beckmann CCA, Wlodarski MW, Muller P, Van Essen D, Rambold A, Kapp FG, Mione M, Buescher JM, Pearce EL, Polyzos A, Trompouki E. Nat Commun. 2018 Aug 6;9(1):3090. doi: 10.1038/s41467-018-05311-4. PubMed |
| Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms. Chan HL, Beckedorff F, Zhang Y, Garcia-Huidobro J, Jiang H, Colaprico A, Bilbao D, Figueroa ME, LaCava J, Shiekhattar R, Morey L. Nat Commun. 2018 Aug 23;9(1):3377. doi: 10.1038/s41467-018-05728-x. PubMed |
| E4BP4 promotes thyroid cancer proliferation by modulating iron homeostasis through repression of hepcidin. Zhou Q, Chen J, Feng J, Wang J. Cell Death Dis. 2018 Sep 24;9(10):987. doi: 10.1038/s41419-018-1001-3. PubMed |
| Notch signaling dynamically regulates adult beta cell proliferation and maturity. Bartolome A, Zhu C, Sussel L, Pajvani UB. J Clin Invest. 2019 Jan 2;129(1):268-280. doi: 10.1172/JCI98098. Epub 2018 Dec 3. PubMed |
| SOX9 is a dose-dependent metastatic fate determinant in melanoma. Yang X, Liang R, Liu C, Liu JA, Cheung MPL, Liu X, Man OY, Guan XY, Lung HL, Cheung M. J Exp Clin Cancer Res. 2019 Jan 14;38(1):17. doi: 10.1186/s13046-018-0998-6. PubMed |
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