Fuw-dCas9-Tet1CD-P2A-BFP Citations (8)
Originally described in: Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene.Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R Cell. 2018 Feb 8. pii: S0092-8674(18)30049-7. doi: 10.1016/j.cell.2018.01.012. PubMed Journal
Articles Citing Fuw-dCas9-Tet1CD-P2A-BFP
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Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons. Graef JD, Wu H, Ng C, Sun C, Villegas V, Qadir D, Jesseman K, Warren ST, Jaenisch R, Cacace A, Wallace O. Eur J Neurosci. 2020 May;51(10):2143-2157. doi: 10.1111/ejn.14660. Epub 2020 Feb 4. PubMed |
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene. Halmai JANM, Deng P, Gonzalez CE, Coggins NB, Cameron D, Carter JL, Buchanan FKB, Waldo JJ, Lock SR, Anderson JD, O'Geen H, Segal DJ, Nolta J, Fink KD. Nucleic Acids Res. 2020 Mar 18;48(5):2372-2387. doi: 10.1093/nar/gkz1214. PubMed |
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation. Douillet D, Sze CC, Ryan C, Piunti A, Shah AP, Ugarenko M, Marshall SA, Rendleman EJ, Zha D, Helmin KA, Zhao Z, Cao K, Morgan MA, Singer BD, Bartom ET, Smith ER, Shilatifard A. Nat Genet. 2020 Jun;52(6):615-625. doi: 10.1038/s41588-020-0618-1. Epub 2020 May 11. PubMed |
p53-intact cancers escape tumor suppression through loss of long noncoding RNA Dino. Marney CB, Anderson ES, Adnan M, Peng KL, Hu Y, Weinhold N, Schmitt AM. Cell Rep. 2021 Jun 29;35(13):109329. doi: 10.1016/j.celrep.2021.109329. PubMed |
Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9.
Sapozhnikov DM, Szyf M.
Nat Commun. 2021 Sep 29;12(1):5711. doi: 10.1038/s41467-021-25991-9.
PubMed
Associated Plasmids |
CRISPR/Cas9-mediated demethylation of FOXP3-TSDR toward Treg-characteristic programming of Jurkat T cells. Wilk C, Effenberg L, Abberger H, Steenpass L, Hansen W, Zeschnigk M, Kirschning C, Buer J, Kehrmann J. Cell Immunol. 2022 Jan;371:104471. doi: 10.1016/j.cellimm.2021.104471. Epub 2021 Dec 20. PubMed |
Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing. Rohm D, Black JB, McCutcheon SR, Barrera A, Morone DJ, Nuttle X, de Esch CE, Tai DJC, Talkowski ME, Iglesias N, Gersbach CA. bioRxiv [Preprint]. 2024 Mar 4:2024.03.03.583177. doi: 10.1101/2024.03.03.583177. PubMed |
CRISPR/dCas9-Tet1-Mediated DNA Methylation Editing. Qian J, Liu SX. Bio Protoc. 2024 Apr 20;14(8):e4976. doi: 10.21769/BioProtoc.4976. eCollection 2024 Apr 20. PubMed |
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