pMKO.1 puro hTERT shRNA Citations (5)
Originally described in: The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.Masutomi K, Possemato R, Wong JM, Currier JL, Tothova Z, Manola JB, Ganesan S, Lansdorp PM, Collins K, Hahn WC Proc Natl Acad Sci U S A. 2005 Jun 7. 102(23):8222-7. PubMed Journal
Articles Citing pMKO.1 puro hTERT shRNA
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Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions. Gonzalez OG, Assfalg R, Koch S, Schelling A, Meena JK, Kraus J, Lechel A, Katz SF, Benes V, Scharffetter-Kochanek K, Kestler HA, Gunes C, Iben S. Nat Commun. 2014 Aug 13;5:4599. doi: 10.1038/ncomms5599. PubMed |
Derepression of hTERT gene expression promotes escape from oncogene-induced cellular senescence. Patel PL, Suram A, Mirani N, Bischof O, Herbig U. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5024-33. doi: 10.1073/pnas.1602379113. Epub 2016 Aug 8. PubMed |
Telomerase reverse transcriptase promotes chemoresistance by suppressing cisplatin-dependent apoptosis in osteosarcoma cells. Zhang Z, Yu L, Dai G, Xia K, Liu G, Song Q, Tao C, Gao T, Guo W. Sci Rep. 2017 Aug 1;7(1):7070. doi: 10.1038/s41598-017-07204-w. PubMed |
Induction of Telomere Dysfunction Prolongs Disease Control of Therapy-Resistant Melanoma. Zhang G, Wu LW, Mender I, Barzily-Rokni M, Hammond MR, Ope O, Cheng C, Vasilopoulos T, Randell S, Sadek N, Beroard A, Xiao M, Tian T, Tan J, Saeed U, Sugarman E, Krepler C, Brafford P, Sproesser K, Murugan S, Somasundaram R, Garman B, Wubbenhorst B, Woo J, Yin X, Liu Q, Frederick DT, Miao B, Xu W, Karakousis GC, Xu X, Schuchter LM, Mitchell TC, Kwong LN, Amaravadi RK, Lu Y, Boland GM, Wei Z, Nathanson K, Herbig U, Mills GB, Flaherty KT, Herlyn M, Shay JW. Clin Cancer Res. 2018 Oct 1;24(19):4771-4784. doi: 10.1158/1078-0432.CCR-17-2773. Epub 2018 Mar 21. PubMed |
Telomerase reverse transcriptase coordinates with the epithelial-to-mesenchymal transition through a feedback loop to define properties of breast cancer stem cells. El-Badawy A, Ghoneim NI, Nasr MA, Elkhenany H, Ahmed TA, Ahmed SM, El-Badri N. Biol Open. 2018 Jul 25;7(7). pii: bio.034181. doi: 10.1242/bio.034181. PubMed |
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