pAAV-EFS-SpCas9 Citations (4)
Originally described in: Virus-Mediated Genome Editing via Homology-Directed Repair in Mitotic and Postmitotic Cells in Mammalian Brain.Nishiyama J, Mikuni T, Yasuda R Neuron. 2017 Oct 18. pii: S0896-6273(17)30933-9. doi: 10.1016/j.neuron.2017.10.004. PubMed Journal
Articles Citing pAAV-EFS-SpCas9
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DNA repair protein RAD51 enhances the CRISPR/Cas9-mediated knock-in efficiency in brain neurons. Kurihara T, Kouyama-Suzuki E, Satoga M, Li X, Badawi M, Thiha, Baig DN, Yanagawa T, Uemura T, Mori T, Tabuchi K. Biochem Biophys Res Commun. 2020 Apr 9;524(3):621-628. doi: 10.1016/j.bbrc.2020.01.132. Epub 2020 Feb 4. PubMed |
IQSEC2 Deficiency Results in Abnormal Social Behaviors Relevant to Autism by Affecting Functions of Neural Circuits in the Medial Prefrontal Cortex. Mehta A, Shirai Y, Kouyama-Suzuki E, Zhou M, Yoshizawa T, Yanagawa T, Mori T, Tabuchi K. Cells. 2021 Oct 12;10(10). pii: cells10102724. doi: 10.3390/cells10102724. PubMed |
Semi-automated workflows to quantify AAV transduction in various brain areas and predict gene editing outcome for neurological disorders.
Duarte F, Ramosaj M, Hasanovic E, Regio S, Sipion M, Rey M, Deglon N.
Mol Ther Methods Clin Dev. 2023 Mar 27;29:254-270. doi: 10.1016/j.omtm.2023.03.013. eCollection 2023 Jun 8.
PubMed
Associated Plasmids |
Limitations of Dual-Single Guide RNA CRISPR Strategies for the Treatment of Central Nervous System Genetic Disorders. Duarte F, Vachey G, Caron NS, Sipion M, Rey M, Perrier AL, Hayden MR, Deglon N. Hum Gene Ther. 2023 Sep;34(17-18):958-974. doi: 10.1089/hum.2023.109. PubMed |
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