pC0046-EF1a-PspCas13b-NES-HIV Citations (19)
Originally described in: RNA editing with CRISPR-Cas13.Cox DBT, Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, Zhang F Science. 2017 Oct 25. pii: eaaq0180. doi: 10.1126/science.aaq0180. PubMed Journal
Articles Citing pC0046-EF1a-PspCas13b-NES-HIV
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Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.
Konermann S, Lotfy P, Brideau NJ, Oki J, Shokhirev MN, Hsu PD.
Cell. 2018 Mar 8. pii: S0092-8674(18)30207-1. doi: 10.1016/j.cell.2018.02.033.
PubMed
Associated Plasmids |
Programmable Inhibition and Detection of RNA Viruses Using Cas13. Freije CA, Myhrvold C, Boehm CK, Lin AE, Welch NL, Carter A, Metsky HC, Luo CY, Abudayyeh OO, Gootenberg JS, Yozwiak NL, Zhang F, Sabeti PC. Mol Cell. 2019 Dec 5;76(5):826-837.e11. doi: 10.1016/j.molcel.2019.09.013. Epub 2019 Oct 10. PubMed |
CRISPR-Cas13d mediates robust RNA virus interference in plants. Mahas A, Aman R, Mahfouz M. Genome Biol. 2019 Dec 2;20(1):263. doi: 10.1186/s13059-019-1881-2. PubMed |
Massively parallel Cas13 screens reveal principles for guide RNA design.
Wessels HH, Mendez-Mancilla A, Guo X, Legut M, Daniloski Z, Sanjana NE.
Nat Biotechnol. 2020 Jun;38(6):722-727. doi: 10.1038/s41587-020-0456-9. Epub 2020 Mar 16.
PubMed
Associated Plasmids
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Abrogation of PRRSV infectivity by CRISPR-Cas13b-mediated viral RNA cleavage in mammalian cells. Cui J, Techakriengkrai N, Nedumpun T, Suradhat S. Sci Rep. 2020 Jun 15;10(1):9617. doi: 10.1038/s41598-020-66775-3. PubMed |
Potent programmable antiviral against dengue virus in primary human cells by Cas13b RNP with short spacer and delivery by VLP. Singsuksawat E, Onnome S, Posiri P, Suphatrakul A, Srisuk N, Nantachokchawapan R, Praneechit H, Sae-Kow C, Chidpratum P, Sa-Ngiamsuntorn K, Hongeng S, Avirutnan P, Duangchinda T, Siridechadilok B. Mol Ther Methods Clin Dev. 2021 Jun 11;21:729-740. doi: 10.1016/j.omtm.2021.04.014. Epub 2021 May 1. PubMed |
In vivo discovery of RNA proximal proteins via proximity-dependent biotinylation. Lin X, Fonseca MAS, Breunig JJ, Corona RI, Lawrenson K. RNA Biol. 2021 May 19:1-15. doi: 10.1080/15476286.2021.1917215. PubMed |
Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance.
Fareh M, Zhao W, Hu W, Casan JML, Kumar A, Symons J, Zerbato JM, Fong D, Voskoboinik I, Ekert PG, Rudraraju R, Purcell DFJ, Lewin SR, Trapani JA.
Nat Commun. 2021 Jul 13;12(1):4270. doi: 10.1038/s41467-021-24577-9.
PubMed
Associated Plasmids |
The Bacterial Enzyme RfxCas13d Is Less Neurotoxic Than PspCas13b and Could Be a Promising RNA Editing and Interference Tool in the Nervous System. Wu QW, Kapfhammer JP. Brain Sci. 2021 Aug 9;11(8):1054. doi: 10.3390/brainsci11081054. PubMed |
Targeted inhibition of Zika virus infection in human cells by CRISPR-Cas13b. Chen P, Chen M, Chen Y, Jing X, Zhang N, Zhou X, Li X, Long G, Hao P. Virus Res. 2022 Apr 15;312:198707. doi: 10.1016/j.virusres.2022.198707. Epub 2022 Feb 9. PubMed |
Enhancer RNA Transcription Is Essential for a Novel CSF1 Enhancer in Triple-Negative Breast Cancer. Lewis MW, Wisniewska K, King CM, Li S, Coffey A, Kelly MR, Regner MJ, Franco HL. Cancers (Basel). 2022 Apr 6;14(7). pii: cancers14071852. doi: 10.3390/cancers14071852. PubMed |
PERSIST platform provides programmable RNA regulation using CRISPR endoRNases. DiAndreth B, Wauford N, Hu E, Palacios S, Weiss R. Nat Commun. 2022 May 11;13(1):2582. doi: 10.1038/s41467-022-30172-3. PubMed |
A cell-cycle-dependent GARP-like transcriptional repressor regulates the initiation of differentiation in Giardia lamblia.
Shih HW, Alas GCM, Paredez AR.
Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2204402119. doi: 10.1073/pnas.2204402119. Epub 2022 May 25.
PubMed
Associated Plasmids |
Optimization of specific RNA knockdown in mammalian cells with CRISPR-Cas13. Burris BJD, Molina Vargas AM, Park BJ, O'Connell MR. Methods. 2022 Oct;206:58-68. doi: 10.1016/j.ymeth.2022.08.007. Epub 2022 Aug 17. PubMed |
Genetically encoded chemical crosslinking of RNA in vivo. Sun W, Wang N, Liu H, Yu B, Jin L, Ren X, Shen Y, Wang L. Nat Chem. 2023 Jan;15(1):21-32. doi: 10.1038/s41557-022-01038-4. Epub 2022 Oct 6. PubMed |
Pseudoknot-targeting Cas13b combats SARS-CoV-2 infection by suppressing viral replication. Yu D, Han HJ, Yu J, Kim J, Lee GH, Yang JH, Song BM, Tark D, Choi BS, Kang SM, Heo WD. Mol Ther. 2023 Jun 7;31(6):1675-1687. doi: 10.1016/j.ymthe.2023.03.018. Epub 2023 Mar 21. PubMed |
A strategy for Cas13 miniaturization based on the structure and AlphaFold. Zhao F, Zhang T, Sun X, Zhang X, Chen L, Wang H, Li J, Fan P, Lai L, Sui T, Li Z. Nat Commun. 2023 Sep 8;14(1):5545. doi: 10.1038/s41467-023-41320-8. PubMed |
Cas13b-mediated RNA targeted therapy alleviates genetic dilated cardiomyopathy in mice. Li J, Xuan H, Kuang X, Li Y, Lian H, Yu N. Cell Biosci. 2024 Jan 4;14(1):4. doi: 10.1186/s13578-023-01143-y. PubMed |
Suppression of Borna Disease Virus Replication during Its Persistent Infection Using the CRISPR/Cas13b System. Sasaki S, Ogawa H, Katoh H, Honda T. Int J Mol Sci. 2024 Mar 20;25(6):3523. doi: 10.3390/ijms25063523. PubMed |
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