pLKO.1P shNFS1_1 Citations (3)
Originally described in: NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis.Alvarez SW, Sviderskiy VO, Terzi EM, Papagiannakopoulos T, Moreira AL, Adams S, Sabatini DM, Birsoy K, Possemato R Nature. 2017 Nov 22. doi: 10.1038/nature24637. PubMed Journal
Articles Citing pLKO.1P shNFS1_1
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| Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function. Ward NP, Kang YP, Falzone A, Boyle TA, DeNicola GM. J Exp Med. 2020 Jun 1;217(6). pii: 151572. doi: 10.1084/jem.20191689. PubMed |
Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase epsilon.
Sviderskiy VO, Blumenberg L, Gorodetsky E, Karakousi TR, Hirsh N, Alvarez SW, Terzi EM, Kaparos E, Whiten GC, Ssebyala S, Tonzi P, Mir H, Neel BG, Huang TT, Adams S, Ruggles KV, Possemato R.
Mol Cell. 2020 Oct 28. pii: S1097-2765(20)30723-1. doi: 10.1016/j.molcel.2020.10.016.
PubMed
Associated Plasmids |
| Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC. Ward NP, Yoon SJ, Flynn T, Sherwood AM, Olley MA, Madej J, DeNicola GM. Nat Commun. 2024 May 18;15(1):4244. doi: 10.1038/s41467-024-48695-2. PubMed |
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