pCMV-ABE7.10 Citations (34)
Originally described in: Programmable base editing of A*T to G*C in genomic DNA without DNA cleavage.Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR Nature. 2017 Nov 23;551(7681):464-471. doi: 10.1038/nature24644. Epub 2017 Oct 25. PubMed Journal
Articles Citing pCMV-ABE7.10
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Highly efficient RNA-guided base editing in rabbit. Liu Z, Chen M, Chen S, Deng J, Song Y, Lai L, Li Z. Nat Commun. 2018 Jul 13;9(1):2717. doi: 10.1038/s41467-018-05232-2. PubMed |
Minimal PAM specificity of a highly similar SpCas9 ortholog.
Chatterjee P, Jakimo N, Jacobson JM.
Sci Adv. 2018 Oct 24;4(10):eaau0766. doi: 10.1126/sciadv.aau0766. eCollection 2018 Oct.
PubMed
Associated Plasmids |
Precise A*T to G*C base editing in the zebrafish genome. Qin W, Lu X, Liu Y, Bai H, Li S, Lin S. BMC Biol. 2018 Nov 20;16(1):139. doi: 10.1186/s12915-018-0609-1. PubMed |
Expanded targeting scope and enhanced base editing efficiency in rabbit using optimized xCas9(3.7). Liu Z, Chen M, Shan H, Chen S, Xu Y, Song Y, Zhang Q, Yuan H, Ouyang H, Li Z, Lai L. Cell Mol Life Sci. 2019 Apr 27. pii: 10.1007/s00018-019-03110-8. doi: 10.1007/s00018-019-03110-8. PubMed |
CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors. Lee C, Hyun Jo D, Hwang GH, Yu J, Kim JH, Park SE, Kim JS, Kim JH, Bae S. Mol Ther. 2019 May 24. pii: S1525-0016(19)30227-8. doi: 10.1016/j.ymthe.2019.05.013. PubMed |
BEAT: A Python Program to Quantify Base Editing from Sanger Sequencing. Xu L, Liu Y, Han R. CRISPR J. 2019 Aug;2:223-229. doi: 10.1089/crispr.2019.0017. Epub 2019 Jul 18. PubMed |
Cytosine base editor 4 but not adenine base editor generates off-target mutations in mouse embryos. Lee HK, Smith HE, Liu C, Willi M, Hennighausen L. Commun Biol. 2020 Jan 9;3(1):19. doi: 10.1038/s42003-019-0745-3. PubMed |
Enabling large-scale genome editing at repetitive elements by reducing DNA nicking.
Smith CJ, Castanon O, Said K, Volf V, Khoshakhlagh P, Hornick A, Ferreira R, Wu CT, Guell M, Garg S, Ng AHM, Myllykallio H, Church GM.
Nucleic Acids Res. 2020 May 21;48(9):5183-5195. doi: 10.1093/nar/gkaa239.
PubMed
Associated Plasmids |
Targeted point mutations of the m6A modification in miR675 using RNA-guided base editing induce cell apoptosis. Hao J, Li C, Lin C, Hao Y, Yu X, Xia Y, Gao F, Jiang Z, Wang D. Biosci Rep. 2020 May 29;40(5):BSR20192933. doi: 10.1042/BSR20192933. PubMed |
BEON: A Functional Fluorescence Reporter for Quantification and Enrichment of Adenine Base-Editing Activity. Wang P, Xu L, Gao Y, Han R. Mol Ther. 2020 Jul 8;28(7):1696-1705. doi: 10.1016/j.ymthe.2020.04.009. Epub 2020 Apr 16. PubMed |
Multiplex precise base editing in cynomolgus monkeys. Zhang W, Aida T, Del Rosario RCH, Wilde JJ, Ding C, Zhang X, Baloch Z, Huang Y, Tang Y, Li D, Lu H, Zhou Y, Jiang M, Xu D, Fang Z, Zheng Z, Huang Q, Feng G, Yang S. Nat Commun. 2020 May 11;11(1):2325. doi: 10.1038/s41467-020-16173-0. PubMed |
Dual base editor catalyzes both cytosine and adenine base conversions in human cells.
Zhang X, Zhu B, Chen L, Xie L, Yu W, Wang Y, Li L, Yin S, Yang L, Hu H, Han H, Li Y, Wang L, Chen G, Ma X, Geng H, Huang W, Pang X, Yang Z, Wu Y, Siwko S, Kurita R, Nakamura Y, Yang L, Liu M, Li D.
Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0527-y. doi: 10.1038/s41587-020-0527-y.
PubMed
Associated Plasmids |
Base editors for simultaneous introduction of C-to-T and A-to-G mutations.
Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, Aburatani H, Yachie N.
Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0509-0. doi: 10.1038/s41587-020-0509-0.
PubMed
Associated Plasmids |
AcrIIA5 Suppresses Base Editors and Reduces Their Off-Target Effects. Liang M, Sui T, Liu Z, Chen M, Liu H, Shan H, Lai L, Li Z. Cells. 2020 Jul 27;9(8). pii: cells9081786. doi: 10.3390/cells9081786. PubMed |
sgBE: a structure-guided design of sgRNA architecture specifies base editing window and enables simultaneous conversion of cytosine and adenosine. Wang Y, Zhou L, Tao R, Liu N, Long J, Qin F, Tang W, Yang Y, Chen Q, Yao S. Genome Biol. 2020 Aug 28;21(1):222. doi: 10.1186/s13059-020-02137-6. PubMed |
Base editing: a brief review and a practical example. Choe DC, Musunuru K. J Biomed Res. 2020 Jul 31;35(2):107-114. doi: 10.7555/JBR.34.20200003. PubMed |
Aglycosylated antibody-producing mice for aglycosylated antibody-lectin coupled immunoassay for the quantification of tumor markers (ALIQUAT). Lee NE, Kim SH, Yu DY, Woo EJ, Kim MI, Seong GS, Lee SM, Ko JH, Kim YS. Commun Biol. 2020 Oct 30;3(1):636. doi: 10.1038/s42003-020-01363-9. PubMed |
One-step genotyping method in CRISPR based on short inner primer-assisted, tetra primer-paired amplifications. Lee NE, Ha DI, Ko JH, Kim YS. Mol Cell Probes. 2021 Feb;55:101675. doi: 10.1016/j.mcp.2020.101675. Epub 2020 Nov 25. PubMed |
A blueprint for gene function analysis through Base Editing in the model plant Physcomitrium (Physcomitrella) patens. Guyon-Debast A, Alboresi A, Terret Z, Charlot F, Berthier F, Vendrell-Mir P, Casacuberta JM, Veillet F, Morosinotto T, Gallois JL, Nogue F. New Phytol. 2021 May;230(3):1258-1272. doi: 10.1111/nph.17171. Epub 2021 Feb 6. PubMed |
Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy. Sikrova D, Cadar VA, Ariyurek Y, Laros JFJ, Balog J, van der Maarel SM. Mol Ther Nucleic Acids. 2021 Jun 1;25:342-354. doi: 10.1016/j.omtn.2021.05.020. eCollection 2021 Sep 3. PubMed |
Delete_A selectable all-in-one CRISPR prime editing piggyBac transposon allows for highly efficient gene editing in human cell lines. Eggenschwiler R, Gschwendtberger T, Felski C, Jahn C, Langer F, Sterneckert J, Hermann A, Luhmann J, Steinemann D, Haase A, Martin U, Petri S, Cantz T. Sci Rep. 2021 Nov 12;11(1):22154. doi: 10.1038/s41598-021-01689-2. PubMed |
Highly efficient A-to-G base editing by ABE8.17 in rabbits. Zhao D, Qian Y, Li J, Li Z, Lai L. Mol Ther Nucleic Acids. 2022 Jan 28;27:1156-1163. doi: 10.1016/j.omtn.2022.01.019. eCollection 2022 Mar 8. PubMed |
Multiplex base- and prime-editing with drive-and-process CRISPR arrays.
Yuan Q, Gao X.
Nat Commun. 2022 May 19;13(1):2771. doi: 10.1038/s41467-022-30514-1.
PubMed
Associated Plasmids |
A framework to efficiently describe and share reproducible DNA materials and construction protocols. Mori H, Yachie N. Nat Commun. 2022 May 24;13(1):2894. doi: 10.1038/s41467-022-30588-x. PubMed |
Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals. Sankar A, Mohammad F, Sundaramurthy AK, Wang H, Lerdrup M, Tatar T, Helin K. Nat Genet. 2022 Jun;54(6):754-760. doi: 10.1038/s41588-022-01091-2. Epub 2022 Jun 6. PubMed |
PAM-flexible dual base editor-mediated random mutagenesis and self-activation strategies to improve CRISPRa potency. Lau CH, Huang S, Lam RHW, Tin C. Mol Ther Methods Clin Dev. 2022 May 29;26:26-37. doi: 10.1016/j.omtm.2022.05.005. eCollection 2022 Sep 8. PubMed |
Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency. Luo L, Shi Y, Wang H, Wang Z, Dang Y, Li S, Wang S, Zhang K. PLoS Genet. 2022 Jul 5;18(7):e1010307. doi: 10.1371/journal.pgen.1010307. eCollection 2022 Jul. PubMed |
In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice. Rovai A, Chung B, Hu Q, Hook S, Yuan Q, Kempf T, Schmidt F, Grimm D, Talbot SR, Steinbruck L, Gotting J, Bohne J, Krooss SA, Ott M. Nat Commun. 2022 Sep 5;13(1):5215. doi: 10.1038/s41467-022-32906-9. PubMed |
Translational enhancement by base editing of the Kozak sequence rescues haploinsufficiency.
Ambrosini C, Destefanis E, Kheir E, Broso F, Alessandrini F, Longhi S, Battisti N, Pesce I, Dassi E, Petris G, Cereseto A, Quattrone A.
Nucleic Acids Res. 2022 Oct 14;50(18):10756-10771. doi: 10.1093/nar/gkac799.
PubMed
Associated Plasmids |
Single-nucleotide editing for zebra3 and wsl5 phenotypes in rice using CRISPR/Cas9-mediated adenine base editors. Molla KA, Shih J, Yang Y. aBIOTECH. 2020 Apr 6;1(2):106-118. doi: 10.1007/s42994-020-00018-x. eCollection 2020 Apr. PubMed |
Expanded MutaT7 toolkit efficiently and simultaneously accesses all possible transition mutations in bacteria. Mengiste AA, Wilson RH, Weissman RF, Papa Iii LJ, Hendel SJ, Moore CL, Butty VL, Shoulders MD. Nucleic Acids Res. 2023 Apr 11;51(6):e31. doi: 10.1093/nar/gkad003. PubMed |
Highly Efficient A-to-G Editing in PFFs via Multiple ABEs. Jing Q, Liu W, Jiang H, Liao Y, Yang Q, Xing Y. Genes (Basel). 2023 Apr 13;14(4):908. doi: 10.3390/genes14040908. PubMed |
Use of adenine base editing and homology-independent targeted integration strategies to correct the cystic fibrosis causing variant, W1282X. Mention K, Cavusoglu-Doran K, Joynt AT, Santos L, Sanz D, Eastman AC, Merlo C, Langfelder-Schwind E, Scallan MF, Farinha CM, Cutting GR, Sharma N, Harrison PT. Hum Mol Genet. 2023 Nov 17;32(23):3237-3248. doi: 10.1093/hmg/ddad143. PubMed |
Primate Model Carrying LMNA Mutation Develops Dilated Cardiomyopathy. Luo X, Jia H, Wang F, Mo H, Kang Y, Zhang N, Zhao L, Xu L, Yang Z, Yang Q, Chang Y, Li S, Bian N, Hua X, Cui H, Cao Y, Chu C, Zeng Y, Chen X, Chen Z, Ji W, Long C, Song J, Niu Y. JACC Basic Transl Sci. 2024 Jan 24;9(3):380-395. doi: 10.1016/j.jacbts.2023.11.002. eCollection 2024 Mar. PubMed |
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