PPRE X3-TK-luc Citations (76)
Originally described in: ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand.Kim JB, Wright HM, Wright M, Spiegelman BM Proc Natl Acad Sci U S A 1998 Apr 14;95(8):4333-7. PubMed Journal
Articles Citing PPRE X3-TK-luc
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| Identification of Arx transcriptional targets in the developing basal forebrain. Fulp CT, Cho G, Marsh ED, Nasrallah IM, Labosky PA, Golden JA. Hum Mol Genet. 2008 Dec 1;17(23):3740-60. doi: 10.1093/hmg/ddn271. Epub 2008 Sep 16. PubMed |
| Salacia oblonga extract increases glucose transporter 4-mediated glucose uptake in L6 rat myotubes: role of mangiferin. Giron MD, Sevillano N, Salto R, Haidour A, Manzano M, Jimenez ML, Rueda R, Lopez-Pedrosa JM. Clin Nutr. 2009 Oct;28(5):565-74. doi: 10.1016/j.clnu.2009.04.018. Epub 2009 May 23. PubMed |
| Increased lipid oxidation causes oxidative stress, increased peroxisome proliferator-activated receptor-gamma expression, and diminished pro-osteogenic Wnt signaling in the skeleton. Almeida M, Ambrogini E, Han L, Manolagas SC, Jilka RL. J Biol Chem. 2009 Oct 2;284(40):27438-48. doi: 10.1074/jbc.M109.023572. Epub 2009 Aug 5. PubMed |
| DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. Ansems M, Hontelez S, Looman MW, Karthaus N, Bult P, Bonenkamp JJ, Jansen JH, Sweep FC, Span PN, Adema GJ. J Natl Cancer Inst. 2010 Jan 6;102(1):54-68. doi: 10.1093/jnci/djp441. Epub 2009 Dec 14. PubMed |
| Obesity reduces bone density associated with activation of PPARgamma and suppression of Wnt/beta-catenin in rapidly growing male rats. Chen JR, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Shankar K, Badger TM, Ronis MJ. PLoS One. 2010 Oct 28;5(10):e13704. doi: 10.1371/journal.pone.0013704. PubMed |
| Therapeutic potential of panduratin A, LKB1-dependent AMP-activated protein kinase stimulator, with activation of PPARalpha/delta for the treatment of obesity. Kim D, Lee MS, Jo K, Lee KE, Hwang JK. Diabetes Obes Metab. 2011 Jul;13(7):584-93. doi: 10.1111/j.1463-1326.2011.01379.x. PubMed |
| Organotins are potent activators of PPARgamma and adipocyte differentiation in bone marrow multipotent mesenchymal stromal cells. Yanik SC, Baker AH, Mann KK, Schlezinger JJ. Toxicol Sci. 2011 Aug;122(2):476-88. doi: 10.1093/toxsci/kfr140. Epub 2011 May 27. PubMed |
| Piperidine alkaloids from Piper retrofractum Vahl. protect against high-fat diet-induced obesity by regulating lipid metabolism and activating AMP-activated protein kinase. Kim KJ, Lee MS, Jo K, Hwang JK. Biochem Biophys Res Commun. 2011 Jul 22;411(1):219-25. doi: 10.1016/j.bbrc.2011.06.153. Epub 2011 Jun 29. PubMed |
| Stereoisomers ginsenosides-20(S)-Rg(3) and -20(R)-Rg(3) differentially induce angiogenesis through peroxisome proliferator-activated receptor-gamma. Kwok HH, Guo GL, Lau JK, Cheng YK, Wang JR, Jiang ZH, Keung MH, Mak NK, Yue PY, Wong RN. Biochem Pharmacol. 2012 Apr 1;83(7):893-902. doi: 10.1016/j.bcp.2011.12.039. Epub 2012 Jan 4. PubMed |
| 5,7-Dimethoxyflavone, an activator of PPARalpha/gamma, inhibits UVB-induced MMP expression in human skin fibroblast cells. Kim JK, Mun S, Kim MS, Kim MB, Sa BK, Hwang JK. Exp Dermatol. 2012 Mar;21(3):211-6. doi: 10.1111/j.1600-0625.2011.01435.x. PubMed |
| Ginsenoside Rb(1) induces type I collagen expression through peroxisome proliferator-activated receptor-delta. Kwok HH, Yue PY, Mak NK, Wong RN. Biochem Pharmacol. 2012 Aug 15;84(4):532-9. doi: 10.1016/j.bcp.2012.05.023. Epub 2012 Jun 9. PubMed |
| The corepressor NCoR1 antagonizes PGC-1alpha and estrogen-related receptor alpha in the regulation of skeletal muscle function and oxidative metabolism. Perez-Schindler J, Summermatter S, Salatino S, Zorzato F, Beer M, Balwierz PJ, van Nimwegen E, Feige JN, Auwerx J, Handschin C. Mol Cell Biol. 2012 Dec;32(24):4913-24. doi: 10.1128/MCB.00877-12. Epub 2012 Oct 1. PubMed |
| 15-Deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) protects neurons from oxidative death via an Nrf2 astrocyte-specific mechanism independent of PPARgamma. Haskew-Layton RE, Payappilly JB, Xu H, Bennett SA, Ratan RR. J Neurochem. 2013 Feb;124(4):536-47. doi: 10.1111/jnc.12107. Epub 2013 Jan 3. PubMed |
| Disruption of Stard10 gene alters the PPARalpha-mediated bile acid homeostasis. Ito M, Yamanashi Y, Toyoda Y, Izumi-Nakaseko H, Oda S, Sugiyama A, Kuroda M, Suzuki H, Takada T, Adachi-Akahane S. Biochim Biophys Acta. 2013 Feb;1831(2):459-68. doi: 10.1016/j.bbalip.2012.11.008. Epub 2012 Nov 28. PubMed |
| Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARalpha). Thomas M, Burk O, Klumpp B, Kandel BA, Damm G, Weiss TS, Klein K, Schwab M, Zanger UM. Mol Pharmacol. 2013 Mar;83(3):709-18. doi: 10.1124/mol.112.082503. Epub 2013 Jan 7. PubMed |
| Mechanisms Mediating the Effects of gamma-Tocotrienol When Used in Combination with PPARgamma Agonists or Antagonists on MCF-7 and MDA-MB-231 Breast Cancer Cells. Malaviya A, Sylvester PW. Int J Breast Cancer. 2013;2013:101705. doi: 10.1155/2013/101705. Epub 2013 Jan 28. PubMed |
| Curcumin inhibits oxLDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation. Min KJ, Um HJ, Cho KH, Kwon TK. Food Chem Toxicol. 2013 Aug;58:77-85. doi: 10.1016/j.fct.2013.04.008. Epub 2013 Apr 16. PubMed |
| Cubilin expression is monoallelic and epigenetically augmented via PPARs. Aseem O, Barth JL, Klatt SC, Smith BT, Argraves WS. BMC Genomics. 2013 Jun 18;14:405. doi: 10.1186/1471-2164-14-405. PubMed |
| Divergence between human and murine peroxisome proliferator-activated receptor alpha ligand specificities. Oswal DP, Balanarasimha M, Loyer JK, Bedi S, Soman FL, Rider SD Jr, Hostetler HA. J Lipid Res. 2013 Sep;54(9):2354-65. doi: 10.1194/jlr.M035436. Epub 2013 Jun 24. PubMed |
| Constituents from Terminalia species increase PPARalpha and PPARgamma levels and stimulate glucose uptake without enhancing adipocyte differentiation. Yang MH, Vasquez Y, Ali Z, Khan IA, Khan SI. J Ethnopharmacol. 2013 Sep 16;149(2):490-8. doi: 10.1016/j.jep.2013.07.003. Epub 2013 Jul 10. PubMed |
| Screening of medicinal plants for PPARalpha and PPARgamma activation and evaluation of their effects on glucose uptake and 3T3-L1 adipogenesis. Yang MH, Avula B, Smillie T, Khan IA, Khan SI. Planta Med. 2013 Aug;79(12):1084-95. doi: 10.1055/s-0033-1350620. Epub 2013 Jul 22. PubMed |
| Panduratin A, an activator of PPAR-alpha/delta, suppresses the development of oxazolone-induced atopic dermatitis-like symptoms in hairless mice. Kim MS, Pyun HB, Hwang JK. Life Sci. 2014 Mar 28;100(1):45-54. doi: 10.1016/j.lfs.2014.01.076. Epub 2014 Feb 11. PubMed |
| Synergistic Antiproliferative Effects of Combined gamma -Tocotrienol and PPAR gamma Antagonist Treatment Are Mediated through PPAR gamma -Independent Mechanisms in Breast Cancer Cells. Malaviya A, Sylvester PW. PPAR Res. 2014;2014:439146. doi: 10.1155/2014/439146. Epub 2014 Mar 4. PubMed |
| A single amino acid change humanizes long-chain fatty acid binding and activation of mouse peroxisome proliferator-activated receptor alpha. Oswal DP, Alter GM, Rider SD Jr, Hostetler HA. J Mol Graph Model. 2014 Jun;51:27-36. doi: 10.1016/j.jmgm.2014.04.006. Epub 2014 Apr 29. PubMed |
| Repression of phosphoinositide-dependent protein kinase 1 expression by ciglitazone via Egr-1 represents a new approach for inhibition of lung cancer cell growth. Hann SS, Tang Q, Zheng F, Zhao S, Chen J, Wang Z. Mol Cancer. 2014 Jun 13;13:149. doi: 10.1186/1476-4598-13-149. PubMed |
| Ligand binding and activation of PPARgamma by Firemaster(R) 550: effects on adipogenesis and osteogenesis in vitro. Pillai HK, Fang M, Beglov D, Kozakov D, Vajda S, Stapleton HM, Webster TF, Schlezinger JJ. Environ Health Perspect. 2014 Nov;122(11):1225-32. doi: 10.1289/ehp.1408111. Epub 2014 Jul 25. PubMed |
| In silico identification of an aryl hydrocarbon receptor antagonist with biological activity in vitro and in vivo. Parks AJ, Pollastri MP, Hahn ME, Stanford EA, Novikov O, Franks DG, Haigh SE, Narasimhan S, Ashton TD, Hopper TG, Kozakov D, Beglov D, Vajda S, Schlezinger JJ, Sherr DH. Mol Pharmacol. 2014 Nov;86(5):593-608. doi: 10.1124/mol.114.093369. Epub 2014 Aug 26. PubMed |
| Soy protein isolate inhibits high-fat diet-induced senescence pathways in osteoblasts to maintain bone acquisition in male rats. Chen JR, Lazarenko OP, Blackburn ML, Badger TM, Ronis MJ. Endocrinology. 2015 Feb;156(2):475-87. doi: 10.1210/en.2014-1427. Epub 2014 Dec 9. PubMed |
| Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA. Buchner DA, Charrier A, Srinivasan E, Wang L, Paulsen MT, Ljungman M, Bridges D, Saltiel AR. J Biol Chem. 2015 Mar 6;290(10):6376-86. doi: 10.1074/jbc.M114.623736. Epub 2015 Jan 16. PubMed |
| Structurally-diverse, PPARgamma-activating environmental toxicants induce adipogenesis and suppress osteogenesis in bone marrow mesenchymal stromal cells. Watt J, Schlezinger JJ. Toxicology. 2015 May 4;331:66-77. doi: 10.1016/j.tox.2015.03.006. Epub 2015 Mar 14. PubMed |
| HIF2alpha-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma. Qiu B, Ackerman D, Sanchez DJ, Li B, Ochocki JD, Grazioli A, Bobrovnikova-Marjon E, Diehl JA, Keith B, Simon MC. Cancer Discov. 2015 Jun;5(6):652-67. doi: 10.1158/2159-8290.CD-14-1507. Epub 2015 Mar 31. PubMed |
| Activation of peroxisome proliferator-activated receptor alpha stimulates ADAM10-mediated proteolysis of APP. Corbett GT, Gonzalez FJ, Pahan K. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8445-50. doi: 10.1073/pnas.1504890112. Epub 2015 Jun 15. PubMed |
| CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor alpha in Human Liver. Makia NL, Goldstein JA. Mol Pharmacol. 2016 Jan;89(1):154-64. doi: 10.1124/mol.115.100255. Epub 2015 Oct 14. PubMed |
| PPARalpha (Peroxisome Proliferator-activated Receptor alpha) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition. Ramakrishnan SK, Khuder SS, Al-Share QY, Russo L, Abdallah SL, Patel PR, Heinrich G, Muturi HT, Mopidevi BR, Oyarce AM, Shah YM, Sanchez ER, Najjar SM. J Biol Chem. 2016 Apr 8;291(15):8121-9. doi: 10.1074/jbc.M116.714014. Epub 2016 Feb 4. PubMed |
| The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, Stunkel W. Development. 2016 Mar 15;143(6):950-61. doi: 10.1242/dev.131573. Epub 2016 Feb 18. PubMed |
| Apple polyphenol extract improves insulin sensitivity in vitro and in vivo in animal models of insulin resistance. Manzano M, Giron MD, Vilchez JD, Sevillano N, El-Azem N, Rueda R, Salto R, Lopez-Pedrosa JM. Nutr Metab (Lond). 2016 Apr 30;13:32. doi: 10.1186/s12986-016-0088-8. eCollection 2016. PubMed |
| Generalized Concentration Addition modeling predicts mixture effects of environmental PPARgamma agonists. Watt J, Webster TF, Schlezinger JJ. Toxicol Sci. 2016 Jun 2. pii: kfw100. PubMed |
| Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice. Charrier A, Wang L, Stephenson EJ, Ghanta SV, Ko CW, Croniger CM, Bridges D, Buchner DA. Am J Physiol Endocrinol Metab. 2016 Nov 1;311(5):E869-E880. doi: 10.1152/ajpendo.00234.2016. Epub 2016 Sep 13. PubMed |
| Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein alpha. Song Z, Xiaoli AM, Zhang Q, Zhang Y, Yang EST, Wang S, Chang R, Zhang ZD, Yang G, Strich R, Pessin JE, Yang F. J Biol Chem. 2017 May 26;292(21):8918-8932. doi: 10.1074/jbc.M117.776229. Epub 2017 Mar 28. PubMed |
| Fatty Acids of CLA-Enriched Egg Yolks Can Induce Transcriptional Activation of Peroxisome Proliferator-Activated Receptors in MCF-7 Breast Cancer Cells. Koronowicz AA, Banks P, Master A, Domagala D, Piasna-Slupecka E, Drozdowska M, Sikora E, Laidler P. PPAR Res. 2017;2017:2865283. doi: 10.1155/2017/2865283. Epub 2017 Mar 26. PubMed |
| Plasmid transfection in bovine cells: Optimization using a realtime monitoring of green fluorescent protein and effect on gene reporter assay. Osorio JS, Bionaz M. Gene. 2017 Aug 30;626:200-208. doi: 10.1016/j.gene.2017.05.025. Epub 2017 May 10. PubMed |
| A PPARgamma-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis. Lee A, Papangeli I, Park Y, Jeong HN, Choi J, Kang H, Jo HN, Kim J, Chun HJ. Sci Rep. 2017 May 31;7(1):2528. doi: 10.1038/s41598-017-02852-4. PubMed |
| In Vitro Differentiation of Preosteoblast-Like Cells, MC3T3-E1, to Adipocytes Is Enhanced by 1,25(OH)2 Vitamin D3. Pendleton E, Chandar N. Front Endocrinol (Lausanne). 2017 Jun 16;8:128. doi: 10.3389/fendo.2017.00128. eCollection 2017. PubMed |
| Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance. Lee SY, Lee HY, Song JH, Kim GT, Jeon S, Song YJ, Lee JS, Hur JH, Oh HH, Park SY, Shim SM, Yoo HJ, Lee BC, Jiang XC, Choi CS, Park TS. Diabetes. 2017 Oct;66(10):2596-2609. doi: 10.2337/db16-1232. Epub 2017 Jul 11. PubMed |
| SMARCD1 regulates senescence-associated lipid accumulation in hepatocytes. Inoue C, Zhao C, Tsuduki Y, Udono M, Wang L, Nomura M, Katakura Y. NPJ Aging Mech Dis. 2017 Aug 30;3:11. doi: 10.1038/s41514-017-0011-1. eCollection 2017. PubMed |
| Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation. Halstead AM, Kapadia CD, Bolzenius J, Chu CE, Schriefer A, Wartman LD, Bowman GR, Arora VK. Elife. 2017 Nov 16;6. pii: 30862. doi: 10.7554/eLife.30862. PubMed |
| N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R. Neuropharmacology. 2019 Apr;148:320-331. doi: 10.1016/j.neuropharm.2018.03.020. Epub 2018 Mar 19. PubMed |
| Lanthionine synthetase C-like protein 2 (LanCL2) is important for adipogenic differentiation. Dutta D, Lai KY, Reyes-Ordonez A, Chen J, van der Donk WA. J Lipid Res. 2018 Aug;59(8):1433-1445. doi: 10.1194/jlr.M085274. Epub 2018 Jun 7. PubMed |
| Identification and characterization of phytocannabinoids as novel dual PPARalpha/gamma agonists by a computational and in vitro experimental approach. D'Aniello E, Fellous T, Iannotti FA, Gentile A, Allara M, Balestrieri F, Gray R, Amodeo P, Vitale RM, Di Marzo V. Biochim Biophys Acta Gen Subj. 2019 Mar;1863(3):586-597. doi: 10.1016/j.bbagen.2019.01.002. Epub 2019 Jan 3. PubMed |
| MiR-30c/PGC-1beta protects against diabetic cardiomyopathy via PPARalpha. Yin Z, Zhao Y, He M, Li H, Fan J, Nie X, Yan M, Chen C, Wang DW. Cardiovasc Diabetol. 2019 Jan 11;18(1):7. doi: 10.1186/s12933-019-0811-7. PubMed |
| Recurrent activating mutations of PPARgamma associated with luminal bladder tumors. Rochel N, Krucker C, Coutos-Thevenot L, Osz J, Zhang R, Guyon E, Zita W, Vanthong S, Hernandez OA, Bourguet M, Badawy KA, Dufour F, Peluso-Iltis C, Heckler-Beji S, Dejaegere A, Kamoun A, de Reynies A, Neuzillet Y, Rebouissou S, Beraud C, Lang H, Massfelder T, Allory Y, Cianferani S, Stote RH, Radvanyi F, Bernard-Pierrot I. Nat Commun. 2019 Jan 16;10(1):253. doi: 10.1038/s41467-018-08157-y. PubMed |
| Loss of Hepatic Oscillatory Fed microRNAs Abrogates Refed Transition and Causes Liver Dysfunctions. Maniyadath B, Chattopadhyay T, Verma S, Kumari S, Kulkarni P, Banerjee K, Lazarus A, Kokane SS, Shetty T, Anamika K, Kolthur-Seetharam U. Cell Rep. 2019 Feb 19;26(8):2212-2226.e7. doi: 10.1016/j.celrep.2019.01.087. PubMed |
| EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes. Moren B, Hansson B, Negoita F, Fryklund C, Lundmark R, Goransson O, Stenkula KG. Mol Biol Cell. 2019 May 1;30(10):1147-1159. doi: 10.1091/mbc.E18-10-0680. Epub 2019 Feb 27. PubMed |
| The Furan Fatty Acid 9M5 Acts as a Partial Ligand to Peroxisome Proliferator-Activated Receptor gamma and Enhances Adipogenesis in 3T3-L1 Preadipocytes. Lauvai J, Becker AK, Lehnert K, Schumacher M, Hieronimus B, Vetter W, Graeve L. Lipids. 2019 May;54(5):277-288. doi: 10.1002/lipd.12152. PubMed |
| RNase MCPIP1 regulates hepatic peroxisome proliferator-activated receptor gamma via TXNIP/PGC-1alpha pathway. Pydyn N, Kadluczka J, Kus E, Pospiech E, Losko M, Fu M, Jura J, Kotlinowski J. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1458-1471. doi: 10.1016/j.bbalip.2019.06.006. Epub 2019 Jun 8. PubMed |
| Essential role of the PGC-1alpha/PPARbeta axis in Ucp3 gene induction. Lima TI, Guimaraes D, Sponton CH, Bajgelman MC, Palameta S, Toscaro JM, Reis O, Silveira LR. J Physiol. 2019 Jun 22. doi: 10.1113/JP278006. PubMed |
| Cyclin-Dependent Kinase 5 Inhibitor Butyrolactone I Elicits a Partial Agonist Activity of Peroxisome Proliferator-Activated Receptor gamma. Ahn S, Jang DM, Park SC, An S, Shin J, Han BW, Noh M. Biomolecules. 2020 Feb 11;10(2). pii: biom10020275. doi: 10.3390/biom10020275. PubMed |
| NIK links inflammation to hepatic steatosis by suppressing PPARalpha in alcoholic liver disease. Li Y, Chen M, Zhou Y, Tang C, Zhang W, Zhong Y, Chen Y, Zhou H, Sheng L. Theranostics. 2020 Feb 18;10(8):3579-3593. doi: 10.7150/thno.40149. eCollection 2020. PubMed |
| The Rosmarinus Bioactive Compound Carnosic Acid Is a Novel PPAR Antagonist That Inhibits the Browning of White Adipocytes. Colson C, Batrow PL, Gautier N, Rochet N, Ailhaud G, Peiretti F, Amri EZ. Cells. 2020 Nov 7;9(11). pii: cells9112433. doi: 10.3390/cells9112433. PubMed |
| RNA-bound PGC-1alpha controls gene expression in liquid-like nuclear condensates. Perez-Schindler J, Kohl B, Schneider-Heieck K, Leuchtmann AB, Henriquez-Olguin C, Adak V, Maier G, Delezie J, Sakoparnig T, Vargas-Fernandez E, Karrer-Cardel B, Ritz D, Schmidt A, Hondele M, Jensen TE, Hiller S, Handschin C. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2105951118. doi: 10.1073/pnas.2105951118. PubMed |
| miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention. Smith AJ, Do P, Sompel K, Elango A, Tennis MA. Sci Rep. 2022 Feb 11;12(1):2388. doi: 10.1038/s41598-022-06292-7. PubMed |
| Phthalate monoesters act through peroxisome proliferator-activated receptors in the mouse ovary. Meling DD, De La Torre KM, Arango AS, Gonsioroski A, Deviney ARK, Neff AM, Laws MJ, Warner GR, Tajkhorshid E, Flaws JA. Reprod Toxicol. 2022 Jun;110:113-123. doi: 10.1016/j.reprotox.2022.04.002. Epub 2022 Apr 11. PubMed |
| The effect of black seed (Nigella sativa) extract on lipid metabolism in HepG2 cells. Haas MJ, Naem E, Almdallaleh S, Mooradian AD. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Aug;1867(8):159155. doi: 10.1016/j.bbalip.2022.159155. Epub 2022 Apr 26. PubMed |
| Ethyl Gallate Dual-Targeting PTPN6 and PPARgamma Shows Anti-Diabetic and Anti-Obese Effects. Ahn D, Kim J, Nam G, Zhao X, Kwon J, Hwang JY, Kim JK, Yoon SY, Chung SJ. Int J Mol Sci. 2022 Apr 30;23(9):5020. doi: 10.3390/ijms23095020. PubMed |
| Iloprost requires the Frizzled-9 receptor to prevent lung cancer. Sompel K, Dwyer-Nield LD, Smith AJ, Elango A, Backos DS, Zhang B, Gross J, Ternyak K, Matsuda JL, Kopf K, Keith RL, Tennis MA. iScience. 2022 May 23;25(6):104442. doi: 10.1016/j.isci.2022.104442. eCollection 2022 Jun 17. PubMed |
| The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation. Song Z, Xiaoli AM, Li Y, Siqin G, Wu T, Strich R, Pessin JE, Yang F. Mol Metab. 2022 Oct;64:101548. doi: 10.1016/j.molmet.2022.101548. Epub 2022 Jul 19. PubMed |
| Loss of Frizzled 9 in Lung Cells Alters Epithelial Phenotype and Promotes Premalignant Lesion Development. Sompel K, Dwyer-Nield LD, Smith AJ, Elango AP, Vanderlinden LA, Kopf K, Keith RL, Tennis MA. Front Oncol. 2022 Jul 18;12:815737. doi: 10.3389/fonc.2022.815737. eCollection 2022. PubMed |
| PFO5DoDA disrupts hepatic homeostasis primarily through glucocorticoid signaling inhibition. Wang C, Fu H, Yang J, Liu L, Zhang F, Yang C, Li H, Chen J, Li Q, Wang X, Ye Y, Sheng N, Guo Y, Dai J, Xu G, Liu X, Wang J. J Hazard Mater. 2023 Apr 5;447:130831. doi: 10.1016/j.jhazmat.2023.130831. Epub 2023 Jan 20. PubMed |
| Tissue-engineered models of lung cancer premalignancy. Blomberg R, Sompel K, Hauer C, Pe A B, Driscoll J, Hume PS, Merrick DT, Tennis MA, Magin CM. bioRxiv. 2023 Mar 16:2023.03.15.532835. doi: 10.1101/2023.03.15.532835. Preprint. PubMed |
| Interaction between poly(A)-binding protein PABPC4 and nuclear receptor corepressor NCoR1 modulates a metabolic stress response. Oliveira AG, Oliveira LD, Cruz MV, Guimaraes DSPSF, Lima TI, Santos-Favero BC, Luchessi AD, Pauletti BA, Leme AP, Bajgelman MC, Afonso J, Regitano LCA, Carvalho HF, Carneiro EM, Kobarg J, Perissi V, Auwerx J, Silveira LR. J Biol Chem. 2023 Jun;299(6):104702. doi: 10.1016/j.jbc.2023.104702. Epub 2023 Apr 12. PubMed |
| Vitamin B2 enables regulation of fasting glucose availability. Masschelin PM, Saha P, Ochsner SA, Cox AR, Kim KH, Felix JB, Sharp R, Li X, Tan L, Park JH, Wang L, Putluri V, Lorenzi PL, Nuotio-Antar AM, Sun Z, Kaipparettu BA, Putluri N, Moore DD, Summers SA, McKenna NJ, Hartig SM. Elife. 2023 Jul 7;12:e84077. doi: 10.7554/eLife.84077. PubMed |
| Hydrogel-Embedded Precision-Cut Lung Slices Model Lung Cancer Premalignancy Ex Vivo. Blomberg R, Sompel K, Hauer C, Smith AJ, Pena B, Driscoll J, Hume PS, Merrick DT, Tennis MA, Magin CM. Adv Healthc Mater. 2024 Feb;13(4):e2302246. doi: 10.1002/adhm.202302246. Epub 2023 Nov 27. PubMed |
| CYP1B1 affects the integrity of the blood-brain barrier and oxidative stress in the striatum: An investigation of manganese-induced neurotoxicity. Wu J, Li Y, Tian S, Na S, Wei H, Wu Y, Yang Y, Shen Z, Ding J, Bao S, Liu S, Li L, Feng R, Zhu Y, He C, Yue J. CNS Neurosci Ther. 2024 Mar;30(3):e14633. doi: 10.1111/cns.14633. PubMed |
| Effects of mifepristone on adipocyte differentiation in mouse 3T3-L1 cells. Hashimoto T, Hirano K. Cell Mol Biol Lett. 2024 Mar 29;29(1):45. doi: 10.1186/s11658-024-00559-9. PubMed |
| Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARgamma serine 273 phosphorylation. Haas B, Hass MDS, Voltz A, Vogel M, Walther J, Biswas A, Hass D, Pfeifer A. Mol Metab. 2024 Jul;85:101956. doi: 10.1016/j.molmet.2024.101956. Epub 2024 May 10. PubMed |
| Molecular regulation of PPARgamma/RXRalpha signaling by the novel cofactor ZFP407. Charrier A, Ockunzzi J, Main L, Ghanta SV, Buchner DA. PLoS One. 2024 May 23;19(5):e0294003. doi: 10.1371/journal.pone.0294003. eCollection 2024. PubMed |
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