dCas9 plasmid Citations (4)

Originally described in: dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.
O'Geen H, Ren C, Nicolet CM, Perez AA, Halmai J, Le VM, Mackay JP, Farnham PJ, Segal DJ Nucleic Acids Res. 2017 Sep 29;45(17):9901-9916. doi: 10.1093/nar/gkx578. PubMed Journal

Articles Citing dCas9 plasmid

Articles
Guidelines for optimized gene knockout using CRISPR/Cas9. Campenhout CV, Cabochette P, Veillard AC, Laczik M, Zelisko-Schmidt A, Sabatel C, Dhainaut M, Vanhollebeke B, Gueydan C, Kruys V. Biotechniques. 2019 Jun;66(6):295-302. doi: 10.2144/btn-2018-0187. Epub 2019 May 1. PubMed
Ezh2-dCas9 and KRAB-dCas9 enable engineering of epigenetic memory in a context-dependent manner. O'Geen H, Bates SL, Carter SS, Nisson KA, Halmai J, Fink KD, Rhie SK, Farnham PJ, Segal DJ. Epigenetics Chromatin. 2019 May 3;12(1):26. doi: 10.1186/s13072-019-0275-8. PubMed Associated Plasmids DNMT3L-dCas9 dCas9-DNMT3L NLS-HA-2xMCP-KRAB NLS-HA-2xMCP-Ezh2
Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair. Ferreira da Silva J, Oliveira GP, Arasa-Verge EA, Kagiou C, Moretton A, Timelthaler G, Jiricny J, Loizou JI. Nat Commun. 2022 Feb 9;13(1):760. doi: 10.1038/s41467-022-28442-1. PubMed
Aberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer. Umeh-Garcia M, O'Geen H, Simion C, Gephart MH, Segal DJ, Sweeney CA. Br J Cancer. 2022 Apr 19. pii: 10.1038/s41416-022-01812-8. doi: 10.1038/s41416-022-01812-8. PubMed Associated Plasmids Tet1-dCas9 VP64-dCas9

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