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About Addgene
For over 20 years, our nonprofit repository has been making it easier to access useful research materials and information.
Deposit your plasmids or contribute data — we'll handle storage, distribution, and record-keeping, helping you to share your discoveries with other scientists.
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Scientists Addgene
Addgene has been an exceptionally useful resource for us, both because they can be trusted to supply our plasmids to other labs efficiently, and because we ourselves are constantly ordering reagents of interest that other labs have deposited. Keep up the good work!
La Jolla Institute for Immunology (La Jolla, CA)
Our optogenetic tools are sweeping throughout neuroscience, helping scientists figure out how the brain works. Without Addgene helping provide these to the world, neuroscience would be moving at a much slower pace.
Massachusetts Institute of Technology (Cambridge, MA)
Tools of the Day
Plasmid
Depositor: Chris Garcia
Purpose: Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.
Viral Prep
Depositor: Simon Wiegert
Purpose: Ready-to-use AAV5 particles produced from CaMKII-somBiPOLES-mCerulean (#154948). CamKII-driven expression of soma-targeted BiPOLES for optogenetic inhibition (blue light) and activation (red light). These AAV preparations are suitable purity for injection into animals.
Antibody
Depositor: Institute for Protein Innovation (IPI)
Purpose: Anti-Integrin αVβ6 (Human) chimeric recombinant antibody with fused human variable and rabbit constant domains; binds the particular alpha/beta chain pair, blocks ligand binding/function (RGD-mimetic)