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Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation.

Ma J, Lindquist S
Proc Natl Acad Sci U S A 2001 Dec 18;98(26):14955-60. Epub 2001 Dec 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
1319moPrP(3F4) D177N
1321cytosolic moPrP (3F4)
13917mSecPrP-pCB6+

Antibodies from Article