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Dual-color GRAB sensors for monitoring spatiotemporal serotonin release in vivo

Deng F, Wan J, Li G, Dong H, Xia X, Wang Y, Li X, Zhuang C, Zheng Y, Liu L, Yan Y, Feng J, Zhao Y, Xie H, Li Y
bioRxiv 2023.05.27.542566 (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
208709pDisplay-GRAB_g5-HT2hExpresses the green 5-HT sensor GRAB_g5-HT2h in mammalian cells
208710pDisplay-GRAB_g5-HT2mExpresses the green 5-HT sensor GRAB_g5-HT2m in mammalian cells
208711pDisplay-GRAB_g5-HT3.0Expresses the green 5-HT sensor GRAB_g5-HT3.0 in mammalian cells
208712pDisplay-GRAB_g5-HT3.0mutExpresses the green 5-HT sensor GRAB_g5-HT3.0mut in mammalian cells
208713pDisplay-GRAB_r5-HT1.0Expresses the red 5-HT sensor GRAB_r5-HT1.0 in mammalian cells
208714pDisplay-GRAB_r5-HTmutExpresses the red 5-HT sensor GRAB_r5-HTmut in mammalian cells
208715pAAV-hSyn-DIO-GRAB_g5-HT2hExpresses the green 5-HT sensor GRAB_g5-HT2h in neurons in the presence of Cre recombinase
208716pAAV-hSyn-GRAB_g5-HT2mExpresses the green 5-HT sensor GRAB_g5-HT2m in neurons
208717pAAV-hSyn-GRAB_g5-HT3.0Expresses the green 5-HT sensor GRAB_g5-HT3.0 in neurons
208718pAAV-hSyn-GRAB_g5-HT3.0mutExpresses the green 5-HT sensor GRAB_g5-HT3.0mut in neurons
208719pAAV-hSyn-GRAB_r5-HT1.0Expresses the red 5-HT sensor GRAB_r5-HT1.0 in neurons
208720pAAV-hSyn-GRAB_r5-HTmutExpresses the red 5-HT sensor GRAB_r5-HTmut in neurons
208721pAAV-hSyn-GRAB_g5-HT2hExpresses the green 5-HT sensor GRAB_g5-HT2h in neurons
208722pAAV-EF1a-DIO-GRAB_g5-HT2mExpresses the green 5-HT sensor GRAB_g5-HT2m in neurons in the presence of Cre recombinase
208723pAAV-CaMKII-GRAB_g5-HT3.0Expresses the green 5-HT sensor GRAB_g5-HT3.0 in excitatory neurons
208724pAAV-EF1a-DIO-GRAB_g5-HT3.0mutExpresses the green 5-HT sensor GRAB_g5-HT3.0mut in neurons in the presence of Cre recombinase
208725pAAV-EF1a-DIO-GRAB_r5-HT1.0Expresses the red 5-HT sensor GRAB_r5-HT1.0 in neurons in the presence of Cre recombinase
208726pAAV-EF1a-DIO-GRAB_g5-HT3.0Expresses the green 5-HT sensor GRAB_g5-HT3.0 in neurons in the presence of Cre recombinase
208727pAAV-GfaABC1D-GRAB_g5-HT3.0Expresses the green 5-HT sensor GRAB_g5-HT3.0 in astrocytes

Antibodies from Article