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CRISPR/Cas9 screen for genome-wide interrogation of essential MYC-bound E-boxes in cancer cells.

Kazimierska M, Podralska M, Zurawek M, Wozniak T, Kasprzyk ME, Sura W, Losiewski W, Ziolkowska-Suchanek I, Kluiver J, van den Berg A, Rozwadowska N, Dzikiewicz-Krawczyk A
Mol Oncol. 2023 Nov;17(11):2295-2313. doi: 10.1002/1878-0261.13493. Epub 2023 Aug 7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
173195MYC-CRISPRThis pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

Antibodies from Article