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A genetically encoded fluorescent biosensor for extracellular L-lactate.

Nasu Y, Murphy-Royal C, Wen Y, Haidey JN, Molina RS, Aggarwal A, Zhang S, Kamijo Y, Paquet ME, Podgorski K, Drobizhev M, Bains JS, Lemieux MJ, Gordon GR, Campbell RE
Nat Commun. 2021 Dec 6;12(1):7058. doi: 10.1038/s41467-021-27332-2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
167944pBAD-eLACCO1.1Fluorescent biosensor for extracellular L-lactate
167945pBAD-deLACCOFluorescent biosensor control for extracellular L-lactate
167946pAEMXT-eLACCO1.1Fluorescent biosensor for extracellular L-lactate
167947pAEMXT-deLACCOFluorescent biosensor control for extracellular L-lactate
168788pAAV-hSyn-eLACCO1.1Neuronal expression of fluorescent sensor for extracellular lactate
168789pAAV-CAG-eLACCO1.1Fluorescent sensor for extracellular lactate
168790pAAV-GFAP-eLACCO1.1Astrocyte expression of fluorescent sensor for extracellular lactate

Antibodies from Article