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Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase.

Cantor JR, Abu-Remaileh M, Kanarek N, Freinkman E, Gao X, Louissaint A Jr, Lewis CA, Sabatini DM
Cell. 2017 Apr 6;169(2):258-272.e17. doi: 10.1016/j.cell.2017.03.023. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
87972pLJC1-Rap2A-3xFLAGExpression of Rap2A in mammalian cells
87973pLJM1-Rap2A-3xFLAGExpression of Rap2A in mammalian cells
87974pLJC2-Rap2A-3xFLAG3rd generation lentiviral vector for Expression of Rap2A in mammalian cells
87975pLJC2-UMPS-3xFLAG3rd generation lentiviral vector for Expression of UMPS in mammalian cells
87976pLJC2-UMPS (Y37A, R155A)-3xFLAGExpression of UMPS (Y37A, R155A) in mammalian cells

Antibodies from Article