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The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells.

Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H
J Biol Chem. 2016 May 31. pii: jbc.M116.729467. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
85450pAAV-RSV-SpCas9Express SpCas9 in mammalian cells
85451pAAV-U6-sgRNA-CMV-GFPExpress sgRNA in mammalian cells

Antibodies from Article