The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells.
Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H
J Biol Chem. 2016 May 31. pii: jbc.M116.729467.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
85450 | pAAV-RSV-SpCas9 | Express SpCas9 in mammalian cells |
85451 | pAAV-U6-sgRNA-CMV-GFP | Express sgRNA in mammalian cells |