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SNORD116 and SNORD115 change expression of multiple genes and modify each other's activity.

Falaleeva M, Surface J, Shen M, de la Grange P, Stamm S
Gene. 2015 Jul 26. pii: S0378-1119(15)00848-3. doi: 10.1016/j.gene.2015.07.023. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
67631pcDNA3.1-MBII85-5'SS mutMBII85 snoRNA expression cassett, contains snoRNA in natural intron surrounded by natural exons. To improve snoRNA expression efficiency 5' splice site was mutated to consensus sequence.
67643pcDNA3.1(+)MBII85MBII85 snoRNA expression cassett, contains snoRNA in natural intron surrounded by natural exons.
67644pcDNA3.1(+)MBII-85-3'ss mutMBII85 snoRNA expression cassett, contains snoRNA in natural intron sorounded by natural exons. To improve snoRNA expression efficiency 3' splice site was mutated to consensus sequences.
67645pcDNA3.1(+)MBII-85-5'/3'ss mutMBII85 snoRNA expression cassett, contains snoRNA in natural intron sorounded by natural exons. To improve snoRNA expression efficiency 5' and 3' splice sites were mutated to consensus sequences.
67646pCRII-MBII85 probeantisense RNA probe for RNase protection or nothern
67647pCR4-MBII52-probeantisense RNA probe for RNase protection or nothern

Antibodies from Article