pINDUCER21 (ORF-EG) Citations (25)
Originally described in: The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3665-70. doi: 10.1073/pnas.1019736108. Epub 2011 Feb 9. PubMed Journal
Articles Citing pINDUCER21 (ORF-EG)
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Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3' splice sites within RNA secondary structures.
Kesarwani AK, Ramirez O, Gupta AK, Yang X, Murthy T, Minella AC, Pillai MM.
Oncogene. 2016 Aug 15. doi: 10.1038/onc.2016.279.
PubMed
Associated Plasmids |
Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue. Gierisch ME, Pfistner F, Lopez-Garcia LA, Harder L, Schafer BW, Niggli FK. J Biol Chem. 2016 Dec 23;291(52):26922-26933. doi: 10.1074/jbc.M116.752063. Epub 2016 Nov 8. PubMed |
A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer. Carter EP, Gopsill JA, Gomm JJ, Jones JL, Grose RP. Breast Cancer Res. 2017 Apr 21;19(1):50. doi: 10.1186/s13058-017-0843-4. PubMed |
Haematopoietic stem and progenitor cells from human pluripotent stem cells.
Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ.
Nature. 2017 May 17. doi: 10.1038/nature22370.
PubMed
Associated Plasmids |
RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia. Hospital MA, Jacquel A, Mazed F, Saland E, Larrue C, Mondesir J, Birsen R, Green AS, Lambert M, Sujobert P, Gautier EF, Salnot V, Le Gall M, Decroocq J, Poulain L, Jacque N, Fontenay M, Kosmider O, Recher C, Auberger P, Mayeux P, Bouscary D, Sarry JE, Tamburini J. Leukemia. 2018 Mar;32(3):597-605. doi: 10.1038/leu.2017.284. Epub 2017 Sep 15. PubMed |
Loss of E-cadherin provides tolerance to centrosome amplification in epithelial cancer cells. Rhys AD, Monteiro P, Smith C, Vaghela M, Arnandis T, Kato T, Leitinger B, Sahai E, McAinsh A, Charras G, Godinho SA. J Cell Biol. 2018 Jan 2;217(1):195-209. doi: 10.1083/jcb.201704102. Epub 2017 Nov 13. PubMed |
Clathrin Assembly Defines the Onset and Geometry of Cortical Patterning. Yang Y, Xiong D, Pipathsouk A, Weiner OD, Wu M. Dev Cell. 2017 Nov 20;43(4):507-521.e4. doi: 10.1016/j.devcel.2017.10.028. PubMed |
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells.
Verma N, Pan H, Dore LC, Shukla A, Li QV, Pelham-Webb B, Teijeiro V, Gonzalez F, Krivtsov A, Chang CJ, Papapetrou EP, He C, Elemento O, Huangfu D.
Nat Genet. 2018 Jan;50(1):83-95. doi: 10.1038/s41588-017-0002-y. Epub 2017 Dec 4.
PubMed
Associated Plasmids |
Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Lagrange B, Benaoudia S, Wallet P, Magnotti F, Provost A, Michal F, Martin A, Di Lorenzo F, Py BF, Molinaro A, Henry T. Nat Commun. 2018 Jan 16;9(1):242. doi: 10.1038/s41467-017-02682-y. PubMed |
SOX4 inhibits oligodendrocyte differentiation of embryonic neural stem cells in vitro by inducing Hes5 expression. Braccioli L, Vervoort SJ, Puma G, Nijboer CH, Coffer PJ. Stem Cell Res. 2018 Dec;33:110-119. doi: 10.1016/j.scr.2018.10.005. Epub 2018 Oct 4. PubMed |
ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation. Muller S, Perdikari A, Dapito DH, Sun W, Wollscheid B, Balaz M, Wolfrum C. Front Endocrinol (Lausanne). 2020 Jun 12;11:387. doi: 10.3389/fendo.2020.00387. eCollection 2020. PubMed |
Integrated analysis of patient samples identifies biomarkers for venetoclax efficacy and combination strategies in acute myeloid leukemia. Zhang H, Nakauchi Y, Kohnke T, Stafford M, Bottomly D, Thomas R, Wilmot B, McWeeney SK, Majeti R, Tyner JW. Nat Cancer. 2020 Aug;1(8):826-839. doi: 10.1038/s43018-020-0103-x. Epub 2020 Aug 18. PubMed |
Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation. Deol KK, Crowe SO, Du J, Bisbee HA, Guenette RG, Strieter ER. Mol Cell. 2020 Dec 3;80(5):796-809.e9. doi: 10.1016/j.molcel.2020.10.017. Epub 2020 Nov 5. PubMed |
Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids. Huang L, Desai R, Conrad DN, Leite NC, Akshinthala D, Lim CM, Gonzalez R, Muthuswamy LB, Gartner Z, Muthuswamy SK. Cell Stem Cell. 2021 Jun 3;28(6):1090-1104.e6. doi: 10.1016/j.stem.2021.03.022. Epub 2021 Apr 28. PubMed |
A test of the pioneer factor hypothesis using ectopic liver gene activation. Hansen JL, Loell KJ, Cohen BA. Elife. 2022 Jan 5;11. pii: 73358. doi: 10.7554/eLife.73358. PubMed |
JAM-A interacts with alpha3beta1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells. Tholmann S, Seebach J, Otani T, Florin L, Schnittler H, Gerke V, Furuse M, Ebnet K. Cell Mol Life Sci. 2022 Jan 24;79(2):88. doi: 10.1007/s00018-022-04140-5. PubMed |
Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells. Morris V, Wang D, Li Z, Marion W, Hughes T, Sousa P, Harada T, Sui SH, Naumenko S, Kalfon J, Sensharma P, Falchetti M, Vinicius da Silva R, Candelli T, Schneider P, Margaritis T, Holstege FCP, Pikman Y, Harris M, Stam RW, Orkin SH, Koehler AN, Shalek AK, North TE, Pimkin M, Daley GQ, Lummertz da Rocha E, Rowe RG. Cell Rep. 2022 Apr 26;39(4):110752. doi: 10.1016/j.celrep.2022.110752. PubMed |
Low HER2 expression in normal breast epithelium enables dedifferentiation and malignant transformation via chromatin opening. Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S, Cutillas P, Mohammed H, Grose RP, Ficz G. Dis Model Mech. 2023 Feb 1;16(2):dmm049894. doi: 10.1242/dmm.049894. Epub 2023 Feb 1. PubMed |
PIE-seq: identifying RNA-binding protein targets by dual RNA-deaminase editing and sequencing.
Ruan X, Hu K, Zhang X.
Nat Commun. 2023 Jun 6;14(1):3275. doi: 10.1038/s41467-023-39054-8.
PubMed
Associated Plasmids |
ADAMTS3 restricts cancer invasion in models of early breast cancer progression through enhanced fibronectin degradation. Gibson SV, Madzharova E, Tan AC, Allen MD, Keller UAD, Jones JL, Carter EP, Grose RP. Matrix Biol. 2023 Jun 17:S0945-053X(23)00074-4. doi: 10.1016/j.matbio.2023.06.005. PubMed |
Extra centrosomes induce PIDD1-mediated inflammation and immunosurveillance. Garcia-Carpio I, Braun VZ, Weiler ES, Leone M, Ninerola S, Barco A, Fava LL, Villunger A. EMBO J. 2023 Aug 2:e113510. doi: 10.15252/embj.2023113510. PubMed |
Inactivation of Tumor Suppressor CYLD Inhibits Fibroblast Reprogramming to Pluripotency. Bekas N, Samiotaki M, Papathanasiou M, Mokos P, Pseftogas A, Xanthopoulos K, Thanos D, Mosialos G, Dafou D. Cancers (Basel). 2023 Oct 15;15(20):4997. doi: 10.3390/cancers15204997. PubMed |
RhoU forms homo-oligomers to regulate cellular responses. Clayton NS, Hodge RG, Infante E, Alibhai D, Zhou F, Ridley AJ. J Cell Sci. 2024 Jan 15;137(2):jcs261645. doi: 10.1242/jcs.261645. Epub 2024 Jan 30. PubMed |
AXL/WRNIP1 Mediates Replication Stress Response and Promotes Therapy Resistance and Metachronous Metastasis in HER2+ Breast Cancer. Marquez-Palencia M, Reza Herrera L, Parida PK, Ghosh S, Kim K, Das NM, Gonzalez-Ericsson PI, Sanders ME, Mobley BC, Diegeler S, Aguilera TA, Peng Y, Lewis CM, Arteaga CL, Hanker AB, Whitehurst AW, Lorens JB, Brekken RA, Davis AJ, Malladi S. Cancer Res. 2024 Mar 4;84(5):675-687. doi: 10.1158/0008-5472.CAN-23-1459. PubMed |
Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks. Yuan B, Bi C, Tian Y, Wang J, Jin Y, Alsayegh K, Tehseen M, Yi G, Zhou X, Shao Y, Romero FV, Fischle W, Izpisua Belmonte JC, Hamdan S, Huang Y, Li M. BMC Biol. 2024 Apr 29;22(1):101. doi: 10.1186/s12915-024-01896-z. PubMed |
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